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    CYP1B1-AS1 CYP1B1 antisense RNA 1 [ Homo sapiens (human) ]

    Gene ID: 285154, updated on 30-Oct-2023

    Summary

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    Official Symbol
    CYP1B1-AS1provided by HGNC
    Official Full Name
    CYP1B1 antisense RNA 1provided by HGNC
    Primary source
    HGNC:HGNC:28543
    See related
    Ensembl:ENSG00000232973 AllianceGenome:HGNC:28543
    Gene type
    ncRNA
    RefSeq status
    PREDICTED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    C2orf58
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    Location:
    2p22.2
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (38131105..38181855)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (38137998..38188755)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (38358247..38408997)

    Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene regulator of microtubule dynamics 2 Neighboring gene RMDN2 antisense RNA 1 Neighboring gene zinc finger protein 430 pseudogene Neighboring gene NANOG hESC enhancer GRCh37_chr2:38244929-38245461 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11367 Neighboring gene melanoma risk locus-associated MPRA allelic enhancer 2:38298139 Neighboring gene CYP1B1 promoter Neighboring gene cytochrome P450 family 1 subfamily B member 1 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr2:38326323-38326823 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:38334037-38334776 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:38334777-38335516 Neighboring gene uncharacterized LOC107985871 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr2:38373590-38374789 Neighboring gene RNA, U6 small nuclear 951, pseudogene Neighboring gene uncharacterized LOC102723739 Neighboring gene ribosomal protein L7 pseudogene 12 Neighboring gene uncharacterized LOC105374467

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Functional variant rs10175368 which affects the expression of CYP1B1 plays a protective role against breast cancer in a Chinese Han population.
      Title: Functional variant rs10175368 which affects the expression of CYP1B1 plays a protective role against breast cancer in a Chinese Han population.
    2. FOXO1-regulated lncRNA CYP1B1-AS1 suppresses breast cancer cell proliferation by inhibiting neddylation.
      Title: FOXO1-regulated lncRNA CYP1B1-AS1 suppresses breast cancer cell proliferation by inhibiting neddylation.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    General gene information

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    Markers

    Other Names

    • CYP1B1 antisense RNA 1 (non-protein coding)

    Clone Names

    • MGC34824

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_027252.1 RNA Sequence

      Status: PREDICTED

      Source sequence(s)
      BC031410
      Related
      ENST00000413828.3

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

      Range
      38131105..38181855
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060926.1 Alternate T2T-CHM13v2.0

      Range
      38137998..38188755
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_173652.1: Suppressed sequence

      Description
      NM_173652.1: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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