U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    LOC108281150 CAGE-defined mid-level expression enhancer in LOC400867 intron [ Homo sapiens (human) ]

    Gene ID: 108281150, updated on 10-Oct-2023

    Summary

    Go to the top of the page Help
    Gene symbol
    LOC108281150
    Gene description
    CAGE-defined mid-level expression enhancer in LOC400867 intron
    Gene type
    biological region
    Feature type(s)
    misc_feature: CAGE_cluster
    regulatory: enhancer
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    This genomic element is located in an intron of the uncharacterized LOC400867 non-protein-coding gene. It was defined as a mid-level expression actively transcribed enhancer based on the presence of balanced bidirectional capped transcripts by cap analysis of gene expression (CAGE). It was validated as a functional enhancer by reporter assays in both HeLa and HepG2 cells. [provided by RefSeq, Jul 2016]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    21q22.2
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 21 NC_000021.9 (38906976..38907515)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 21 NC_060945.1 (37290723..37291262)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 21 NC_000021.8 (40278900..40279439)

    Chromosome 21 - NC_000021.9Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101928398 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13317 Neighboring gene ETS2 antisense RNA 1 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr21:40275087-40276286 Neighboring gene ribosomal protein SA pseudogene 64 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:40286344-40286844 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:40286845-40287345 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:40316387-40317085 Neighboring gene ReSE screen-validated silencer GRCh37_chr21:40318461-40318589 Neighboring gene long intergenic non-protein coding RNA 1700 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18464 Neighboring gene VISTA enhancer hs1516 Neighboring gene long intergenic non-protein coding RNA 2940 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18465

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. An atlas of active enhancers across human cell types and tissues. Andersson R, et al. Nature, 2014 Mar 27. PMID 24670763, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

    Go to the top of the page Help

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

    Go to the top of the page Help

    See variants in ClinVar

    See Variation Viewer (GRCh37.p13)

    General gene information

    Go to the top of the page Help

    Other Names

    • LOC400867 intron mid CAGE FANTOM5 enhancer

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_051110.1 

      Range
      101..640
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000021.9 Reference GRCh38.p14 Primary Assembly

      Range
      38906976..38907515
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060945.1 Alternate T2T-CHM13v2.0

      Range
      37290723..37291262
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases