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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 1
1996 2
1999 2
2000 6
2001 3
2002 7
2003 10
2004 4
2005 12
2006 15
2007 9
2008 14
2009 16
2010 23
2011 23
2012 21
2013 27
2014 38
2015 45
2016 50
2017 63
2018 48
2019 68
2020 100
2021 112
2022 98
2023 102
2024 25

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814 results

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Page 1
Tranexamic Acid in Gastrointestinal Bleeding: A Systematic Review and Meta-Analysis.
Dionne JC, Oczkowski SJW, Hunt BJ, Antonelli M, Wijnberge M, Raasveld SJ, Vlaar APJ; for ESICM Transfusion Taskforce and the GUIDE Group. Dionne JC, et al. Crit Care Med. 2022 Mar 1;50(3):e313-e319. doi: 10.1097/CCM.0000000000005362. Crit Care Med. 2022. PMID: 34709209
OBJECTIVES: Tranexamic acid is proposed as a treatment for gastrointestinal bleeding. The Haemorrhage Alleviation with Tranexamic Acid-Intestinal System trial evaluated extended-use (24 hr) high-dose tranexamic acid, prompting a reappraisal for tranexamic acid in …
OBJECTIVES: Tranexamic acid is proposed as a treatment for gastrointestinal bleeding. The Haemorrhage Alleviation with Tranexa …
Corticosteroids and risk of gastrointestinal bleeding: a systematic review and meta-analysis.
Narum S, Westergren T, Klemp M. Narum S, et al. BMJ Open. 2014 May 15;4(5):e004587. doi: 10.1136/bmjopen-2013-004587. BMJ Open. 2014. PMID: 24833682 Free PMC article. Review.
RESULTS: 159 studies (N=33 253) were included. In total, 804 (2.4%) patients had a gastrointestinal bleeding or perforation (2.9% and 2.0% for corticosteroids and placebo). Corticosteroids increased the risk of gastrointestinal bleeding or perforation …
RESULTS: 159 studies (N=33 253) were included. In total, 804 (2.4%) patients had a gastrointestinal bleeding or perforation (2 …
Diagnosis and treatment of iron-deficiency anemia in gastrointestinal bleeding: A systematic review.
Cotter J, Baldaia C, Ferreira M, Macedo G, Pedroto I. Cotter J, et al. World J Gastroenterol. 2020 Dec 7;26(45):7242-7257. doi: 10.3748/wjg.v26.i45.7242. World J Gastroenterol. 2020. PMID: 33362380 Free PMC article.
Iron-deficiency anemia (IDA) often originates from blood loss from lesions in the gastrointestinal tract in men and postmenopausal women, and its prevalence among patients with gastrointestinal bleeding has been estimated to be 61%. However, few guidelines re …
Iron-deficiency anemia (IDA) often originates from blood loss from lesions in the gastrointestinal tract in men and postmenopausal wo …
Restrictive versus liberal blood transfusion for gastrointestinal bleeding: a systematic review and meta-analysis of randomised controlled trials.
Odutayo A, Desborough MJ, Trivella M, Stanley AJ, Dorée C, Collins GS, Hopewell S, Brunskill SJ, Kahan BC, Logan RF, Barkun AN, Murphy MF, Jairath V. Odutayo A, et al. Lancet Gastroenterol Hepatol. 2017 May;2(5):354-360. doi: 10.1016/S2468-1253(17)30054-7. Epub 2017 Mar 23. Lancet Gastroenterol Hepatol. 2017. PMID: 28397699 Review.
BACKGROUND: Acute upper gastrointestinal bleeding is a leading indication for red blood cell (RBC) transfusion worldwide, although optimal thresholds for transfusion are debated. ...INTERPRETATION: These results support more widespread implementation of restrictive …
BACKGROUND: Acute upper gastrointestinal bleeding is a leading indication for red blood cell (RBC) transfusion worldwide, alth …
Efficacy and safety of gastrointestinal bleeding prophylaxis in critically ill patients: systematic review and network meta-analysis.
Wang Y, Ye Z, Ge L, Siemieniuk RAC, Wang X, Wang Y, Hou L, Ma Z, Agoritsas T, Vandvik PO, Perner A, Møller MH, Guyatt GH, Liu L. Wang Y, et al. BMJ. 2020 Jan 6;368:l6744. doi: 10.1136/bmj.l6744. BMJ. 2020. PMID: 31907166 Free PMC article.
OBJECTIVE: To determine, in critically ill patients, the relative impact of proton pump inhibitors (PPIs), histamine-2 receptor antagonists (H2RAs), sucralfate, or no gastrointestinal bleeding prophylaxis (or stress ulcer prophylaxis) on outcomes important to patien …
OBJECTIVE: To determine, in critically ill patients, the relative impact of proton pump inhibitors (PPIs), histamine-2 receptor antagonists …
Vasoactive Agents for the Management of Acute Variceal Bleeding: A Systematic Review and Meta-analysis.
Huaringa-Marcelo J, Huaman MR, Brañez-Condorena A, Villacorta-Landeo P, Pinto-Ruiz DF, Urday-Ipanaqué D, García-Gomero D, Montes-Teves P, Lozano Miranda A. Huaringa-Marcelo J, et al. J Gastrointestin Liver Dis. 2021 Mar 13;30(1):110-121. doi: 10.15403/jgld-3191. J Gastrointestin Liver Dis. 2021. PMID: 33723542 Free article.
BACKGROUND AND AIMS: Vasoactive agents with endoscopic therapy are used to treat acute variceal bleeding (AVB). There are two main groups of vasoactive agents: terlipressin and vasopressin (T-V), and octreotide and somatostatin (O-S). ...Our main outcomes were mortality an …
BACKGROUND AND AIMS: Vasoactive agents with endoscopic therapy are used to treat acute variceal bleeding (AVB). There are two main gr …
Association of Antisecretory Drugs with Upper Gastrointestinal Bleeding in Patients Using Oral Anticoagulants: A Systematic Review and Meta-Analysis.
Kurlander JE, Barnes GD, Fisher A, Gonzalez JJ, Helminski D, Saini SD, Sengupta N, Yang YX, Scheiman J, Laine L. Kurlander JE, et al. Am J Med. 2022 Oct;135(10):1231-1243.e8. doi: 10.1016/j.amjmed.2022.05.031. Epub 2022 Jun 7. Am J Med. 2022. PMID: 35679879 Free PMC article.
BACKGROUND: The role of antisecretory drugs for the prevention of upper gastrointestinal bleeding in patients using anticoagulants is unclear. ...Individual studies showed greater treatment effect in patients with higher risk for upper gastrointestinal ble
BACKGROUND: The role of antisecretory drugs for the prevention of upper gastrointestinal bleeding in patients using anticoagul …
Management of acute upper gastrointestinal bleeding.
Stanley AJ, Laine L. Stanley AJ, et al. BMJ. 2019 Mar 25;364:l536. doi: 10.1136/bmj.l536. BMJ. 2019. PMID: 30910853
Upper gastrointestinal bleeding (UGIB) is a common medical emergency, with a reported mortality of 2-10%. ...Recurrent ulcer bleeding is treated with repeat endoscopic therapy, with subsequent bleeding managed by interventional radiology or surgery. .. …
Upper gastrointestinal bleeding (UGIB) is a common medical emergency, with a reported mortality of 2-10%. ...Recurrent ulcer …
Drug-drug interactions with warfarin: A systematic review and meta-analysis.
Wang M, Zeraatkar D, Obeda M, Lee M, Garcia C, Nguyen L, Agarwal A, Al-Shalabi F, Benipal H, Ahmad A, Abbas M, Vidug K, Holbrook A. Wang M, et al. Br J Clin Pharmacol. 2021 Nov;87(11):4051-4100. doi: 10.1111/bcp.14833. Epub 2021 May 16. Br J Clin Pharmacol. 2021. PMID: 33769581 Free article. Review.
We found a protective effect of proton pump inhibitors (PPIs) against warfarin-related gastrointestinal (GI) bleeding (OR = 0.69; 95% CI 0.64-0.73). No significant effect on thromboembolic events or mortality of any drug group used with warfarin was found, including …
We found a protective effect of proton pump inhibitors (PPIs) against warfarin-related gastrointestinal (GI) bleeding (OR = 0. …
Corticosteroids in septic shock: a systematic review and network meta-analysis.
Gibbison B, López-López JA, Higgins JP, Miller T, Angelini GD, Lightman SL, Annane D. Gibbison B, et al. Crit Care. 2017 Mar 28;21(1):78. doi: 10.1186/s13054-017-1659-4. Crit Care. 2017. PMID: 28351429 Free PMC article. Review.
CONCLUSIONS: There was no clear evidence that any one corticosteroid drug or treatment regimen is more likely to be effective in reducing mortality or reducing the incidence of gastrointestinal bleeding or superinfection in septic shock. Hydrocortisone delivered as …
CONCLUSIONS: There was no clear evidence that any one corticosteroid drug or treatment regimen is more likely to be effective in reducing mo …
814 results