Ibuprofen-arginine generates nitric oxide and has enhanced anti-inflammatory effects.
De Palma C, Di Paola R, Perrotta C, Mazzon E, Cattaneo D, Trabucchi E, Cuzzocrea S, Clementi E.
De Palma C, et al.
Pharmacol Res. 2009 Oct;60(4):221-8. doi: 10.1016/j.phrs.2009.06.002. Epub 2009 Jun 17.
Pharmacol Res. 2009.
PMID: 19539763
We have investigated the pharmacological properties of one such salt, ibuprofen-arginine, of biological interest because l-arginine acts as substrate of the nitric oxide (NO) synthesising enzymes. Using epithelial HeLa cells expressing the endothelial NO synthase we …
We have investigated the pharmacological properties of one such salt, ibuprofen-arginine, of biological interest because l-arg …