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Page 1
Clinical pharmacokinetics of ibuprofen arginine.
Cattaneo D, Clementi E. Cattaneo D, et al. Curr Clin Pharmacol. 2010 Nov;5(4):239-45. doi: 10.2174/157488410793352012. Curr Clin Pharmacol. 2010. PMID: 20925647 Review.
This review will mainly deal with the clinical pharmacokinetics of ibuprofen arginine, an alternative formulation specifically designed to improve the absorption of ibuprofen. ...Taken together, the pharmacokinetic/dynamic characteristics of ibuprofen argi
This review will mainly deal with the clinical pharmacokinetics of ibuprofen arginine, an alternative formulation specifically …
Single-Dose Ibuprofen-Arginine as a Preventive for Pain, Edema, and Trismus After Impacted Lower Third Molar Surgery: A Randomized Split-Mouth Clinical Trial.
Ramos EU, Benetti LP, Oliveira JCS, Bassi APF. Ramos EU, et al. Eur J Dent. 2022 May;16(2):396-402. doi: 10.1055/s-0041-1735910. Epub 2021 Dec 22. Eur J Dent. 2022. PMID: 34937107 Free PMC article.
Patients were randomly assigned numbers from 1 to 21. Group A received ibuprofen-arginine as preoperative medication, while Group B received only ibuprofen. ...RESULTS: The study results reveal that the facial edema scores of Group A and Group B presented statistica …
Patients were randomly assigned numbers from 1 to 21. Group A received ibuprofen-arginine as preoperative medication, while Gr …
Ibuprofen-arginine generates nitric oxide and has enhanced anti-inflammatory effects.
De Palma C, Di Paola R, Perrotta C, Mazzon E, Cattaneo D, Trabucchi E, Cuzzocrea S, Clementi E. De Palma C, et al. Pharmacol Res. 2009 Oct;60(4):221-8. doi: 10.1016/j.phrs.2009.06.002. Epub 2009 Jun 17. Pharmacol Res. 2009. PMID: 19539763
We have investigated the pharmacological properties of one such salt, ibuprofen-arginine, of biological interest because l-arginine acts as substrate of the nitric oxide (NO) synthesising enzymes. Using epithelial HeLa cells expressing the endothelial NO synthase we …
We have investigated the pharmacological properties of one such salt, ibuprofen-arginine, of biological interest because l-arg …
Ibuprofen arginine for pain control during scaling and root planing: a randomized, triple-blind trial.
Ettlin DA, Ettlin A, Bless K, Puhan M, Bernasconi C, Tillmann HC, Palla S, Gallo LM. Ettlin DA, et al. J Clin Periodontol. 2006 May;33(5):345-50. doi: 10.1111/j.1600-051X.2006.00918.x. J Clin Periodontol. 2006. PMID: 16634956 Clinical Trial.
METHODS: This randomized, triple-blind, placebo-controlled, parallel-group trial assessed the analgesic efficacy of ibuprofen arginine (Spedifen) in patients undergoing routine periodontal scaling and root planing. 64 patients with chronic periodontitis received eit …
METHODS: This randomized, triple-blind, placebo-controlled, parallel-group trial assessed the analgesic efficacy of ibuprofen argi
Effect of topical application of ibuprofen/arginine on the in-office bleaching-induced tooth sensitivity: A randomized, triple-blind controlled trial.
Hortkoff D, da Silva KL, Farago PV, Gomes JC, Reis A, Gomes GM. Hortkoff D, et al. J Dent. 2024 Mar;142:104875. doi: 10.1016/j.jdent.2024.104875. Epub 2024 Feb 1. J Dent. 2024. PMID: 38309571 Clinical Trial.
METHODS: Sixty-two participants with upper canine shades A2 or darker were randomly assigned to either the ibuprofen-arginine desensitizing group or the placebo group. The desensitizing gel was applied for 15 min before in-office bleaching with 35 % hydrogen peroxid …
METHODS: Sixty-two participants with upper canine shades A2 or darker were randomly assigned to either the ibuprofen-arginine
GC-MS and GC-MS/MS measurement of ibuprofen in 10-muL aliquots of human plasma and mice serum using [alpha-methylo-(2)H(3)]ibuprofen after ethyl acetate extraction and pentafluorobenzyl bromide derivatization: Discovery of a collision energy-dependent H/D isotope effect and pharmacokinetic application to inhaled ibuprofen-arginine in mice.
Tsikas D, Kayacelebi AA, Hanff E, Mitschke A, Beckmann B, Tillmann HC, Gutzki FM, Müller M, Bernasconi C. Tsikas D, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Feb 1;1043:158-166. doi: 10.1016/j.jchromb.2016.06.014. Epub 2016 Jun 9. J Chromatogr B Analyt Technol Biomed Life Sci. 2017. PMID: 27343144
Effectiveness and tolerability of ibuprofen-arginine versus paracetamol in children with fever of likely infectious origin.
Figueras Nadal C, García de Miguel MJ, Gómez Campderá A, Pou Fernández J, Alvarez Calatayud G, Sánchez Bayle M; Paediatric Fever Co-operative Group from the Spanish Paediatric Association. Figueras Nadal C, et al. Acta Paediatr. 2002;91(4):383-90. doi: 10.1080/080352502317371607. Acta Paediatr. 2002. PMID: 12061352 Clinical Trial.
The resulting efficacy analysis population included a total of 88 patients treated with ibuprofen-arginine and 87 with paracetamol. Mean change in tympanic temperature (degrees C) showed no difference between groups (p = 0.527) but more patients in the ibuprofen
The resulting efficacy analysis population included a total of 88 patients treated with ibuprofen-arginine and 87 with paracet …
Effectiveness of ibuprofen-arginine in the treatment of acute migraine attacks.
Sandrini G, Franchini S, Lanfranchi S, Granella F, Manzoni GC, Nappi G. Sandrini G, et al. Int J Clin Pharmacol Res. 1998;18(3):145-50. Int J Clin Pharmacol Res. 1998. PMID: 9825271 Clinical Trial.
The purpose of this study was to evaluate the effectiveness of a new formulation of ibuprofen (ibuprofen-arginine [IA]) in the treatment of migraine attacks. This is a faster absorbed formulation as compared with ibuprofen alone. ...
The purpose of this study was to evaluate the effectiveness of a new formulation of ibuprofen (ibuprofen-arginine [IA]) in the …
36 results