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Anordiol is more potent than anordrin for terminating pregnancy when administered with RU 486.
Wang WC, Chang CC, Bardin CW. Wang WC, et al. Contraception. 1993 Jun;47(6):609-16. doi: 10.1016/0010-7824(93)90028-6. Contraception. 1993. PMID: 8334895
A smaller dose of anordiol than anordrin is required to achieve this synergistic effect with RU 486. ...Administration of anordiol at doses that do not terminate pregnancy resulted in a significant suppression of serum progesterone concentrations during the period o …
A smaller dose of anordiol than anordrin is required to achieve this synergistic effect with RU 486. ...Administration of anordiol …
Anordiol and RU486 synergize to produce preimplantation pregnancy loss by increasing embryo transport (rat).
Kaplan-Kraicer R, Bardin CW, Shalgi R. Kaplan-Kraicer R, et al. Contraception. 1995 Feb;51(2):141-6. doi: 10.1016/0010-7824(94)00020-w. Contraception. 1995. PMID: 7750292
RU486, an antiprogestational agent, and anordiol (dihydroxylated metabolite of anordrin) which has an estrogenic and antiestrogenic activity, are known to inhibit fertility. ...In combination, anordiol and RU486 had a synergistic effect on embryo transport in the ra …
RU486, an antiprogestational agent, and anordiol (dihydroxylated metabolite of anordrin) which has an estrogenic and antiestrogenic a …
Effects of acetazolamide and anordiol on osmotic water permeability in AQP1-cRNA injected Xenopus oocyte.
Ma B, Xiang Y, Mu SM, Li T, Yu HM, Li XJ. Ma B, et al. Acta Pharmacol Sin. 2004 Jan;25(1):90-7. Acta Pharmacol Sin. 2004. PMID: 14704128 Free article.
AIM: To study the effects of acetazolamide and anordiol on osmotic water permeability in aquaporin 1 (AQP1)-cRNA injected Xenopus oocyte and their mechanisms. ...CONCLUSION: Both acetazolamide and anordiol inhibited the osmotic water permeability of AQP1-cRNA inject …
AIM: To study the effects of acetazolamide and anordiol on osmotic water permeability in aquaporin 1 (AQP1)-cRNA injected Xenopus ooc …
Comparative effectiveness of three antiprogestins alone and in combination with anordiol in terminating pregnancy in the rat.
Dao B, Vanage G, Li XJ, Bardin CW, Koide SS. Dao B, et al. Contraception. 1997 Jan;55(1):35-40. doi: 10.1016/s0010-7824(96)00239-9. Contraception. 1997. PMID: 9013059
Anordiol acted synergistically with all three antiprogestins terminating pregnancy in the rat. The antiprogestins at doses that were either partially effective or non-effective became 100% effective when administered with a non-effective dose of anordiol. Thus, comb …
Anordiol acted synergistically with all three antiprogestins terminating pregnancy in the rat. The antiprogestins at doses that were …
Estrogenic and antiestrogenic activities of anordiol: a comparison of uterine and vaginal responses with those of clomiphene citrate.
Peters AJ, Wentz AC, Kazer RR, Jeyendran RS, Chatterton RT Jr. Peters AJ, et al. Contraception. 1995 Sep;52(3):195-202. doi: 10.1016/0010-7824(95)00151-y. Contraception. 1995. PMID: 7587192
Anordiol (2 alpha,17 alpha-diethynyl-A-nor-5 alpha-androstane-2 beta,17 beta-diol) has been variously characterized as an estrogen and as an antiestrogen. ...Binding affinities and serum E2 and progesterone (P) concentrations were not statistically different among the grou …
Anordiol (2 alpha,17 alpha-diethynyl-A-nor-5 alpha-androstane-2 beta,17 beta-diol) has been variously characterized as an estrogen an …
Anordiol produces pregnancy loss in the rat--via the embryo or via the uterus?
Kaplan-Kraicer R, Shinnar N, Bardin CW, Shalgi R. Kaplan-Kraicer R, et al. Contraception. 2000 May;61(5):341-6. doi: 10.1016/s0010-7824(00)00115-3. Contraception. 2000. PMID: 10906506
Anordiol, the dihydroxylated metabolite of anordrin, is an antiestrogen with estrogenic activity that is known to inhibit fertility. ...In one set of experiments, the donor rats were treated with anordiol, and in the second set the recipient rats were treated. The r …
Anordiol, the dihydroxylated metabolite of anordrin, is an antiestrogen with estrogenic activity that is known to inhibit fertility. …
Anti-uterotrophic and folliculostatic activities of anordiol (2 alpha,17 alpha-diethynyl-A-nor-5 alpha-androstane-2 beta,17 beta-diol).
Chatterton RT Jr, Berman C, Walters NN. Chatterton RT Jr, et al. Contraception. 1989 Mar;39(3):291-7. doi: 10.1016/0010-7824(89)90061-9. Contraception. 1989. PMID: 2714089
In further evaluation of the uterine response to anordiol an increase in uterine wet weight and soluble protein was observed with both 30 and 90 micrograms doses of anordiol at 12, 24, 36, and 48 hours, but not at 6 or 72 hr after a single s.c. injection. ...Anor …
In further evaluation of the uterine response to anordiol an increase in uterine wet weight and soluble protein was observed with bot …
Effect of anordiol on ovarian hormone secretion, ovulation, and uterine and vaginal responses in the immature rat.
Lu YC, Chatterton RT Jr. Lu YC, et al. Adv Contracept. 1994 Jun;10(2):157-66. doi: 10.1007/BF01978109. Adv Contracept. 1994. PMID: 7942263
The purpose of this investigation was to determine the estrogenic and antiestrogenic activities of the potential contraceptive agent anordiol in the immature rat. A dose of 2.45 mumol of anordiol (AD), estradiol (E2), clomiphene citrate (CC), tamoxifen (TA), or the …
The purpose of this investigation was to determine the estrogenic and antiestrogenic activities of the potential contraceptive agent anor …
Effects of the antiestrogen anordiol on ovulation and endometrial histology in the rat.
Lu YC, Chatterton RT Jr. Lu YC, et al. Adv Contracept. 1993 Sep;9(3):257-68. doi: 10.1007/BF01982949. Adv Contracept. 1993. PMID: 8237581
The presence of cornified cells in the vaginal smears 2 days after treatment with anordiol was a result of luteolysis and an intrinsic estrogenic activity of anordiol. Ovulation occurred on the first estrus after treatment whether the animals received 13 treatments …
The presence of cornified cells in the vaginal smears 2 days after treatment with anordiol was a result of luteolysis and an intrinsi …
Effect of mifepristone and antiestrogens on uterine PGF2 alpha and PGE2 concentrations in ovariectomized and pregnant rats.
Li XJ, Yu H, Koide SS. Li XJ, et al. Prostaglandins. 1997 Mar;53(3):187-97. doi: 10.1016/s0090-6980(97)00014-2. Prostaglandins. 1997. PMID: 9206800
Mated rats were treated post-coitally for three consecutive days with anordiol, tamoxifen, estradiol and mifepristone alone and with the combination of anordiol/mifepristone and tamoxifen/mifepristone. ...The changes in PGF2 alpha concentrations induced by anordi …
Mated rats were treated post-coitally for three consecutive days with anordiol, tamoxifen, estradiol and mifepristone alone and with …
25 results