[Conservative treatment of breast cancer]

Med Radiol (Mosk). 1988 May;33(5):5-9.
[Article in Russian]

Abstract

The paper is concerned with clinical characterization of 81 breast cancer patients after conservative radio- and hormonotherapy. Of the total number of patients 47 suffered from inoperable tumors as a result of local spreading, 30 patients had serious contraindications for the operation, and 4 patients refused surgical intervention. Of the total number of patients 85% were aged over 50, 69%--over 60.41%--over 70, and 4 patients--over 80. The results of radiotherapy after a radical program and administration of antiestrogens (tamoxifen, zitosonium) were evaluated in 71 patients: in 42 tumors were undetectable, in 16 they were reduced by more than 50% of their primary size. An analysis of short-term results during 1-year follow-up showed that of 50 patients complete remission was observed in 24, stabilization of a tumor process was achieved in 8. The results should be regarded as promising with relation to the patients' age, status, tumor spreading, and concomitant diseases.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Breast Neoplasms / drug therapy
  • Breast Neoplasms / radiotherapy*
  • Combined Modality Therapy
  • Estrogen Antagonists / therapeutic use
  • Female
  • Humans
  • Middle Aged
  • Organic Chemicals
  • Tamoxifen / therapeutic use

Substances

  • Estrogen Antagonists
  • Organic Chemicals
  • Tamoxifen
  • zitosonium