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Tildipirosin: An effective antibiotic against Glaesserella parasuis from an in vitro analysis.
Peres PR, Prigol SR, Martín CBG, Feronatod C, Suriñach MC, Kreutz LC, Frandoloso R. Peres PR, et al. Vet Anim Sci. 2020 Jul 21;10:100136. doi: 10.1016/j.vas.2020.100136. eCollection 2020 Dec. Vet Anim Sci. 2020. PMID: 32964167 Free PMC article.
Tildipirosin is a latest generation macrolide that is used to battle infection diseases caused by Gram-negative bacteria. ...A total of 90% of G. parasuis isolates were sensitive at concentrations 4 g/mL Tildipirosin, thus showing to be efficiently controlled by the …
Tildipirosin is a latest generation macrolide that is used to battle infection diseases caused by Gram-negative bacteria. ...A total …
Pharmacokinetics of tildipirosin in horses after intravenous and intramuscular administration and its potential muscle damage.
Galecio JS, Escudero E, Badillo E, Marín P. Galecio JS, et al. Res Vet Sci. 2022 Dec 20;152:20-25. doi: 10.1016/j.rvsc.2022.06.033. Epub 2022 Jul 23. Res Vet Sci. 2022. PMID: 35908422
Tildipirosin is a novel semisynthetic macrolide antibiotic exclusively used in veterinary practice to treat respiratory infections. ...Tildipirosin plasma concentrations were determined by HPLC assay with ultraviolet detection. ...
Tildipirosin is a novel semisynthetic macrolide antibiotic exclusively used in veterinary practice to treat respiratory infections. . …
Pharmacokinetics and bioavailability of tildipirosin following intravenous and subcutaneous administration in horses.
Abu-Basha EA, Bani Ismail Z, Ababneh MM, Hamzeh E, Gehring R. Abu-Basha EA, et al. J Vet Pharmacol Ther. 2021 Jul;44(4):544-551. doi: 10.1111/jvp.12958. Epub 2021 Feb 20. J Vet Pharmacol Ther. 2021. PMID: 33609061
For PK analysis, blood samples were collected at pre-determined times before and after tildipirosin administration. Plasma concentrations of tildipirosin were determined using ultra-high-performance liquid chromatography-ultraviolet detection method (UHPLC-UV). ...O …
For PK analysis, blood samples were collected at pre-determined times before and after tildipirosin administration. Plasma concentrat …
Pharmacokinetics of Tildipirosin in Plasma, Milk, and Somatic Cells Following Intravenous, Intramuscular, and Subcutaneous Administration in Dairy Goats.
Galecio JS, Marín P, Hernandis V, Botía M, Escudero E. Galecio JS, et al. Pharmaceutics. 2022 Apr 13;14(4):860. doi: 10.3390/pharmaceutics14040860. Pharmaceutics. 2022. PMID: 35456694 Free PMC article.
Tildipirosin is a macrolide currently authorized for treating respiratory diseases in cattle and swine. The disposition kinetics of tildipirosin in plasma, milk, and somatic cells were investigated in dairy goats. ...
Tildipirosin is a macrolide currently authorized for treating respiratory diseases in cattle and swine. The disposition kinetics of …
Pharmacokinetics and bioavailability of tildipirosin following intravenous and subcutaneous administration in sheep.
Abu-Basha EA, Bani Ismail Z, Abu Alhaijaa H, Hamzeh E, Idkaidek NM. Abu-Basha EA, et al. J Vet Pharmacol Ther. 2021 Jan;44(1):79-85. doi: 10.1111/jvp.12901. Epub 2020 Aug 3. J Vet Pharmacol Ther. 2021. PMID: 32748450
Tildipirosin is a semi-synthetic macrolide antibiotic commonly used in cattle and swine to treat bacterial pneumonia. ...Eighteen lambs were randomly divided into three groups (n = 6 each). Lambs received a single s.c. dose of tildipirosin at 4 and 6 mg/kg b.w. in g …
Tildipirosin is a semi-synthetic macrolide antibiotic commonly used in cattle and swine to treat bacterial pneumonia. ...Eighteen lam …
Enhanced Cellular Delivery of Tildipirosin by Xanthan Gum-Gelatin Composite Nanogels.
Li X, Liu J, Dou J, Li C, Jiang Y, Dawood A, Wei J, Wei Y, Xiong Y, Luo W, Algharib S. Li X, et al. Langmuir. 2024 Mar 5;40(9):4860-4870. doi: 10.1021/acs.langmuir.3c03559. Epub 2024 Feb 23. Langmuir. 2024. PMID: 38394629
Tildipirosin has no significant inhibitory effect on intracellular bacteria because of its poor membrane permeability. ...With those pharmaceutical properties provided by xanthan gum-gelatin composite nanogels, the anti-Staphylococcus aureus activity of tildipirosin …
Tildipirosin has no significant inhibitory effect on intracellular bacteria because of its poor membrane permeability. ...With those …
Pharmacokinetics of tildipirosin in pig tonsils.
Torres F, Santamaria R, Jimenez M, Menjón R, Ibanez A, Collell M, Azlor O, Fraile L. Torres F, et al. J Vet Pharmacol Ther. 2016 Apr;39(2):199-201. doi: 10.1111/jvp.12258. Epub 2015 Aug 12. J Vet Pharmacol Ther. 2016. PMID: 26935349 Clinical Trial.
The penetration of antimicrobials in pig tonsils is hardly known. The objective of the study was to quantify the tildipirosin (TD) penetration in tonsils. Animals were randomly divided into six groups (control, T1, T2 (1), T2(5), T2(10), and T2(15)) of eight animals. ...To …
The penetration of antimicrobials in pig tonsils is hardly known. The objective of the study was to quantify the tildipirosin (TD) pe …
Pharmacokinetics of tildipirosin in beagle dogs.
Wang J, Zhao T, Sun X, Liu Y, Zhu J, Zhang S, Cao X. Wang J, et al. J Vet Pharmacol Ther. 2018 Feb;41(1):e49-e52. doi: 10.1111/jvp.12453. Epub 2017 Sep 11. J Vet Pharmacol Ther. 2018. PMID: 28892155
The objective of this study was to investigate the pharmacokinetic profile of tildipirosin (TD) in 24 beagle dogs following intravenous (i.v.) and intramuscular (i.m.) administration, respectively, at 2, 4, and 6 mg/kg. ...
The objective of this study was to investigate the pharmacokinetic profile of tildipirosin (TD) in 24 beagle dogs following intraveno …
Comparative transcriptional profiling of tildipirosin-resistant and sensitive Haemophilus parasuis.
Lei Z, Fu S, Yang B, Liu Q, Ahmed S, Xu L, Xiong J, Cao J, Qiu Y. Lei Z, et al. Sci Rep. 2017 Aug 8;7(1):7517. doi: 10.1038/s41598-017-07972-5. Sci Rep. 2017. PMID: 28790420 Free PMC article.
Numerous studies have been conducted to examine the molecular mechanism of Haemophilus parasuis resistance to antibiotic, but rarely to tildipirosin. In the current study, transcriptional profiling was applied to analyse the variation in gene expression of JS0135 and ti …
Numerous studies have been conducted to examine the molecular mechanism of Haemophilus parasuis resistance to antibiotic, but rarely to t …
Effect of metaphylactic administration of tildipirosin on the incidence of pneumonia and otitis and on the upper respiratory tract and fecal microbiome of preweaning Holstein calves.
Bringhenti L, Pallu M, Silva J, Tomazi T, Tomazi AC, Rodrigues MX, Duarte LM, Bilby TR, Bicalho RC. Bringhenti L, et al. J Dairy Sci. 2021 May;104(5):6020-6038. doi: 10.3168/jds.2020-19572. Epub 2021 Mar 6. J Dairy Sci. 2021. PMID: 33685693 Free article.
Calves in the TRT group received a single subcutaneous injection of 4 mg/kg tildipirosin (Zuprevo, Merck Animal Health) at 7 7 d of life. Calves in the CTR group received no drug injection. ...The metaphylactic use of tildipirosin can be a suitable strategy for the …
Calves in the TRT group received a single subcutaneous injection of 4 mg/kg tildipirosin (Zuprevo, Merck Animal Health) at 7 7 d of l …
60 results