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Year Number of Results
1989 1
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1993 3
1994 1
1997 1
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Page 1
Interaction of non-guanylate cyclase-linked atriopeptin receptor ligand and endopeptidase inhibitor in conscious rats.
Koepke JP, Tyler LD, Trapani AJ, Bovy PR, Spear KL, Olins GM, Blaine EH. Koepke JP, et al. J Pharmacol Exp Ther. 1989 Apr;249(1):172-6. J Pharmacol Exp Ther. 1989. PMID: 2565386
Converting enzyme inhibition did not contribute to the effects of thiorphan since coadministration of captopril plus SC-46542 produced effects similar to SC-46542 alone. When a near threshold infusion of AP(103-126) was combined with the coadministrati …
Converting enzyme inhibition did not contribute to the effects of thiorphan since coadministration of captopril plus SC-46542 …
Response to atrial natriuretic peptide, endopeptidase 24.11 inhibitor and C-ANP receptor ligand in the rat.
Wilkins MR, Settle SL, Kirk JE, Taylor SA, Moore KP, Unwin RJ. Wilkins MR, et al. Br J Pharmacol. 1992 Sep;107(1):50-7. doi: 10.1111/j.1476-5381.1992.tb14462.x. Br J Pharmacol. 1992. PMID: 1330165 Free PMC article.
Interestingly, there was no increase in FeLi with the combination of the two compounds, suggesting that the major contribution to sodium excretion came from SC 46542.6. Both candoxatrilat and SC 46542 increased sodium and cyclic GMP excretion in the ra …
Interestingly, there was no increase in FeLi with the combination of the two compounds, suggesting that the major contribution to sodium exc …
Effects of natriuretic peptides and nitroprusside on venous function in trout.
Olson KR, Conklin DJ, Farrell AP, Keen JE, Takei Y, Weaver L Jr, Smith MP, Zhang Y. Olson KR, et al. Am J Physiol. 1997 Aug;273(2 Pt 2):R527-39. doi: 10.1152/ajpregu.1997.273.2.R527. Am J Physiol. 1997. PMID: 9277535
In the present studies, the natriuretic peptides (NP) rat atrial natriuretic peptide (ANP) and trout ventricular natriuretic peptide (VNP), clearance receptor inhibitor SC-46542, and sodium nitroprusside (SNP) were infused into unanesthetized trout fitted with press …
In the present studies, the natriuretic peptides (NP) rat atrial natriuretic peptide (ANP) and trout ventricular natriuretic peptide (VNP), …
Atriopeptin regulation and renal function in conscious spontaneously hypertensive rats.
Koepke JP, Tyler LD, Mehta PP, Olins GM, Trapani AJ, Hartupee DA, Bovy PR, Spear KL, Blaine EH. Koepke JP, et al. Am J Hypertens. 1990 Aug;3(8 Pt 1):622-7. doi: 10.1093/ajh/3.8.622. Am J Hypertens. 1990. PMID: 2171564
Coadministration of thiorphan and SC-46542 had no effect on glomerular filtration rate or plasma cGMP concentration, suggesting that the urinary cGMP excretion response was nephrogenous. Compared to vehicle control rats, plasma APir was increased during coadministra …
Coadministration of thiorphan and SC-46542 had no effect on glomerular filtration rate or plasma cGMP concentration, suggestin …
Chronic atriopeptin regulation of arterial pressure in conscious hypertensive rats.
Koepke JP, Tyler LD, Blehm DJ, Schuh JR, Blaine EH. Koepke JP, et al. Hypertension. 1990 Dec;16(6):642-7. doi: 10.1161/01.hyp.16.6.642. Hypertension. 1990. PMID: 2147172
Chronic infusion of atriopeptin-(103-126) decreased mean arterial pressure progressively over the first 3 days; then mean arterial pressure progressively rose to control level over the following 3 days and remained at control level for the remainder of the experiment. Similarly, …
Chronic infusion of atriopeptin-(103-126) decreased mean arterial pressure progressively over the first 3 days; then mean arterial pressure …
Effect of endopeptidase-24.11 inhibition and of atrial natriuretic peptide clearance receptor ligand on the response to rat brain natriuretic peptide in the conscious rat.
Kirk JE, Wilkins MR. Kirk JE, et al. Br J Pharmacol. 1993 Sep;110(1):350-4. doi: 10.1111/j.1476-5381.1993.tb13816.x. Br J Pharmacol. 1993. PMID: 8220896 Free PMC article.
The present studies examined the effect of (a) a specific endopeptidase-24.11 (E-24.11) inhibitor (candoxatrilat) and (b) a ligand for the atrial natriuretic peptide (ANP) clearance receptor (SC 46542) on the renal and blood pressure response to brain natriuretic pe …
The present studies examined the effect of (a) a specific endopeptidase-24.11 (E-24.11) inhibitor (candoxatrilat) and (b) a ligand for the a …
The natriuretic peptides and hypertension.
Richards AM. Richards AM. J Intern Med. 1994 Jun;235(6):543-60. doi: 10.1111/j.1365-2796.1994.tb01262.x. J Intern Med. 1994. PMID: 8207361 Review. No abstract available.
Hydrolysis of human and pig brain natriuretic peptides, urodilatin, C-type natriuretic peptide and some C-receptor ligands by endopeptidase-24.11.
Kenny AJ, Bourne A, Ingram J. Kenny AJ, et al. Biochem J. 1993 Apr 1;291 ( Pt 1)(Pt 1):83-8. doi: 10.1042/bj2910083. Biochem J. 1993. PMID: 8097089 Free PMC article.
The 22-residue C-type natriuretic peptide was hydrolysed more rapidly than alpha-hANP, as were two C-receptor ligands (peptides with deletions within the ring): C-ANP4-23 (rANP4-23 des-Gln18,Ser19,Gly20,Leu21,Gly22) and SC 46542 (hANP5-28 des-Phe8,Gly9,Ala17,Gln18). …
The 22-residue C-type natriuretic peptide was hydrolysed more rapidly than alpha-hANP, as were two C-receptor ligands (peptides with deletio …
Single-pass gill extraction and tissue distribution of atrial natriuretic peptide in trout.
Olson KR, Duff DW. Olson KR, et al. Am J Physiol. 1993 Jul;265(1 Pt 2):R124-31. doi: 10.1152/ajpregu.1993.265.1.R124. Am J Physiol. 1993. PMID: 8342676
Single-pass extraction of 125I-ANP by the gill was 60% in control fish; it fell to 18% in fish previously injected with saline and became negative (relative to 58Co-EDTA) after treatment with the clearance (C-type) receptor inhibitor SC 46542. Approximately 90% of a …
Single-pass extraction of 125I-ANP by the gill was 60% in control fish; it fell to 18% in fish previously injected with saline and became ne …
Atrial natriuretic peptide clearance receptors in trout: effects of receptor inhibition in vivo.
Duff DW, Olson KR. Duff DW, et al. J Exp Zool. 1992 Jun 1;262(3):343-6. doi: 10.1002/jez.1402620315. J Exp Zool. 1992. PMID: 1322447
In the present study arterial blood pressure, urine flow, and urine electrolytes were measured in chronically cannulated rainbow trout, Oncorhynchus mykiss, during infusion of the specific C receptor inhibitor, SC-46542. C receptor inhibition decreased blood pressur …
In the present study arterial blood pressure, urine flow, and urine electrolytes were measured in chronically cannulated rainbow trout, Onco …
11 results