[Diterpenoids from Chinese eaglewood]

Zhongguo Zhong Yao Za Zhi. 2011 Aug;36(15):2088-91.
[Article in Chinese]

Abstract

Column chromatography on silica gel, Sephadex LH-20, semi-preparative HPLC were used to separate and purify the compounds from the petroleum ether and ethanol extract of Chinese eaglewood. Nine compounds were isolated. On the basis of their spectroscopic data, their structures were identified as dehydroabietic acid (1), methyl dehydroabietate (2), methyl 7-oxodehydroabietate (3), 7alpha, 15-dihydroxydehydroabietic acid (4), 7alpha-hydroxypodocarpen-8(14)-en-13-on-18-oic acid (5), pimaric acid (6), pimarol (7), 18-norpimara-8 (14), and 15-dien-4alpha-ol (8), 18-norisopimara-8 (14), 15-dien-4beta-ol (9). All of the compounds were isolated from this plant for the first time, and compounds 5, 8 and 9 are norditerpenoids.

Publication types

  • English Abstract

MeSH terms

  • Diterpenes / chemistry*
  • Diterpenes / isolation & purification
  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / isolation & purification
  • Plants, Medicinal / chemistry*
  • Thymelaeaceae / chemistry*

Substances

  • Diterpenes
  • Drugs, Chinese Herbal