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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1905 1
1910 1
1915 1
1924 1
1935 1
1943 1
1944 1
1945 5
1946 13
1947 16
1948 12
1949 12
1950 20
1951 18
1952 21
1953 19
1954 24
1955 26
1956 15
1957 15
1958 18
1959 10
1960 15
1961 15
1962 44
1963 86
1964 120
1965 101
1966 125
1967 145
1968 152
1969 143
1970 163
1971 179
1972 195
1973 197
1974 215
1975 179
1976 193
1977 193
1978 165
1979 174
1980 162
1981 158
1982 186
1983 167
1984 145
1985 176
1986 186
1987 167
1988 192
1989 185
1990 185
1991 198
1992 154
1993 157
1994 129
1995 125
1996 96
1997 123
1998 111
1999 95
2000 105
2001 78
2002 73
2003 69
2004 66
2005 73
2006 74
2007 80
2008 68
2009 55
2010 62
2011 69
2012 70
2013 71
2014 44
2015 49
2016 41
2017 41
2018 46
2019 42
2020 36
2021 45
2022 28
2023 36
2024 8

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7,418 results

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Page 1
Phenserine.
Klein J. Klein J. Expert Opin Investig Drugs. 2007 Jul;16(7):1087-97. doi: 10.1517/13543784.16.7.1087. Expert Opin Investig Drugs. 2007. PMID: 17594192 Review.
Phenserine, a derivative of physostigmine, was first described as an inhibitor of acetylcholinesterase (AChE) and was shown to improve cognition in various experimental paradigms in rodents and dogs. ...
Phenserine, a derivative of physostigmine, was first described as an inhibitor of acetylcholinesterase (AChE) and was shown to improv …
[Opus posthumous].
Kotsias BA. Kotsias BA. Medicina (B Aires). 2017;77(5):440-441. Medicina (B Aires). 2017. PMID: 29044026 Free article. Spanish. No abstract available.
Physostigmine in mania.
Davis KL, Berger PA, Hollister LE, Defraites E. Davis KL, et al. Arch Gen Psychiatry. 1978 Jan;35(1):119-22. doi: 10.1001/archpsyc.1978.01770250121012. Arch Gen Psychiatry. 1978. PMID: 339869 Clinical Trial.
Seven men and one woman with primary affective disorder, mania, were given a slow intravenous infusion of physostigmine salicylate. In six patients, mood and thought content changed from mania toward depression as evaluated by either a visual analog mood scale or the Pette …
Seven men and one woman with primary affective disorder, mania, were given a slow intravenous infusion of physostigmine salicylate. I …
Toxicology reviews: physostigmine.
Shannon M. Shannon M. Pediatr Emerg Care. 1998 Jun;14(3):224-6. doi: 10.1097/00006565-199806000-00015. Pediatr Emerg Care. 1998. PMID: 9655671 Review. No abstract available.
Ponder physostigmine use.
Slay RD. Slay RD. J Emerg Med. 1985;3(6):485-6. doi: 10.1016/0736-4679(85)90008-3. J Emerg Med. 1985. PMID: 3837049 No abstract available.
Meptazinol.
Weinstock M. Weinstock M. Lancet. 1983 Oct 29;2(8357):1027. doi: 10.1016/s0140-6736(83)91012-7. Lancet. 1983. PMID: 6138571 No abstract available.
Mutasynthesis of Physostigmines in Myxococcus xanthus.
Winand L, Schneider P, Kruth S, Greven NJ, Hiller W, Kaiser M, Pietruszka J, Nett M. Winand L, et al. Org Lett. 2021 Aug 20;23(16):6563-6567. doi: 10.1021/acs.orglett.1c02374. Epub 2021 Aug 6. Org Lett. 2021. PMID: 34355569
The alkaloid physostigmine is an approved anticholinergic drug and an important lead structure for the development of novel therapeutics. Using a complementary approach that merged chemical synthesis with pathway refactoring, we produced a series of physostigmine an …
The alkaloid physostigmine is an approved anticholinergic drug and an important lead structure for the development of novel therapeut …
[Eserine, in Crooked House and Curtain].
Takao M. Takao M. Brain Nerve. 2023 Dec;75(12):1343-1346. doi: 10.11477/mf.1416202536. Brain Nerve. 2023. PMID: 38097226 Japanese.
Eserine, well-known as physostigmine, is classified as an alkaloid. It is a cholinesterase inhibitor and appears in Agatha Christie's novel entitled, Crooked House and Curtain: Poirot's Last Case. ...
Eserine, well-known as physostigmine, is classified as an alkaloid. It is a cholinesterase inhibitor and appears in Agatha Christie's …
Cholinergic therapy in dementia.
Whitehouse PJ. Whitehouse PJ. Acta Neurol Scand Suppl. 1993;149:42-5. doi: 10.1111/j.1600-0404.1993.tb04254.x. Acta Neurol Scand Suppl. 1993. PMID: 8128838 Review.
Phenserine Axonyx.
Thatte U. Thatte U. Curr Opin Investig Drugs. 2005 Jul;6(7):729-39. Curr Opin Investig Drugs. 2005. PMID: 16044670 Review.
The acetylcholinesterase inhibitor phenserine, the (-)-enantiomer of a phenylcarbamate derivative of physostigmine, is being developed as a potential therapy for Alzheimer's disease by Axonyx, under license from the National Institutes of Health/National Institute on Aging …
The acetylcholinesterase inhibitor phenserine, the (-)-enantiomer of a phenylcarbamate derivative of physostigmine, is being develope …
7,418 results