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Mogroside V exerts anti-inflammatory effects on fine particulate matter-induced inflammation in porcine alveolar macrophages.
Shen J, Shen D, Tang Q, Li Z, Jin X, Li C. Shen J, et al. Toxicol In Vitro. 2022 Apr;80:105326. doi: 10.1016/j.tiv.2022.105326. Epub 2022 Feb 5. Toxicol In Vitro. 2022. PMID: 35134483
Mogroside V reduced intracellular ROS levels induced by PM(2.5). In the transcriptomic analysis, inflammation-related genes in 3D4/21 cells were not significantly affected after treatment with mogroside V. ...Mogroside V has a clear anti-
Mogroside V reduced intracellular ROS levels induced by PM(2.5). In the transcriptomic analysis, inflammation-related genes in
Mogroside V reduce OVA-induced pulmonary inflammation based on lung and serum metabolomics.
Liu Y, Wang J, Guan X, Yu D, Huangfu M, Dou T, Zhou L, Wang L, Liu G, Li X, Zhai Z, Han M, Liu H, Chen X. Liu Y, et al. Phytomedicine. 2021 Oct;91:153682. doi: 10.1016/j.phymed.2021.153682. Epub 2021 Aug 21. Phytomedicine. 2021. PMID: 34483017
BACKGROUND: Mogroside V, the main ingredient of Siraitia grosvenorii, has been proved to have therapeutic effects on pulmonary diseases. ...And visceral index of mice treated with mogroside V was close to control group. These results indicated that …
BACKGROUND: Mogroside V, the main ingredient of Siraitia grosvenorii, has been proved to have therapeutic effects on pulmonary …
[Synthetic biology for the synthesis of mogroside V - a review].
Sun Z, Lü B, Feng Y. Sun Z, et al. Sheng Wu Gong Cheng Xue Bao. 2020 Oct 25;36(10):2017-2028. doi: 10.13345/j.cjb.200072. Sheng Wu Gong Cheng Xue Bao. 2020. PMID: 33169567 Review. Chinese.
Mogroside V, a component with high content and sweetness in mogrosides, has many pharmacological activities such as relieving cough, reducing sputum, anti-cancer, anti-oxidation, regulating blood sugar, making it a natural nonsugar sweetener with therapeutic functio
Mogroside V, a component with high content and sweetness in mogrosides, has many pharmacological activities such as relieving
Mogroside V Inhibits Hyperglycemia-induced Lung Cancer Cells Metastasis through Reversing EMT and Damaging Cytoskeleton.
Chen J, Jiao D, Li Y, Jiang C, Tang X, Song J, Chen Q. Chen J, et al. Curr Cancer Drug Targets. 2019;19(11):885-895. doi: 10.2174/1568009619666190619154240. Curr Cancer Drug Targets. 2019. PMID: 31215378
Hyperglycemia, a critical feature of DM, promotes lung cancer metastasis. Mogroside V is a triterpenoid glycoside from Siraitia grosvenorii. Interestingly, mogroside V not only plays an anti-diabetic role, but also has anti-tumor effects. ...
Hyperglycemia, a critical feature of DM, promotes lung cancer metastasis. Mogroside V is a triterpenoid glycoside from Siraiti …
Mogroside V improves porcine oocyte in vitro maturation and subsequent embryonic development.
Nie J, Yan K, Sui L, Zhang H, Zhang H, Yang X, Lu S, Lu K, Liang X. Nie J, et al. Theriogenology. 2020 Jan 1;141:35-40. doi: 10.1016/j.theriogenology.2019.09.010. Epub 2019 Sep 6. Theriogenology. 2020. PMID: 31518726
In the present study, we evaluated the beneficial effects of mogroside V, an extract derived from Siraitia grosvenorii, on oocyte IVM. Porcine cumulus-oocyte complexes were cultured in IVM medium supplemented or not supplemented with mogroside V for 40 …
In the present study, we evaluated the beneficial effects of mogroside V, an extract derived from Siraitia grosvenorii, on ooc …
Mogroside V protects porcine oocytes from in vitro ageing by reducing oxidative stress through SIRT1 upregulation.
Nie J, Sui L, Zhang H, Zhang H, Yan K, Yang X, Lu S, Lu K, Liang X. Nie J, et al. Aging (Albany NY). 2019 Oct 6;11(19):8362-8373. doi: 10.18632/aging.102324. Epub 2019 Oct 6. Aging (Albany NY). 2019. PMID: 31586990 Free PMC article.
We observed that mogroside V can effectively maintain normal oocyte morphology and early embryo development competence after prolonged culture for 24 h. ...We examined the molecular changes and found that SIRT1 expression was decreased in in vitro aged oocytes but w …
We observed that mogroside V can effectively maintain normal oocyte morphology and early embryo development competence after p …
Protective activity of mogroside V against ovalbumin-induced experimental allergic asthma in Kunming mice.
Song JL, Qian B, Pan C, Lv F, Wang H, Gao Y, Zhou Y. Song JL, et al. J Food Biochem. 2019 Sep;43(9):e12973. doi: 10.1111/jfbc.12973. Epub 2019 Jul 24. J Food Biochem. 2019. PMID: 31489660
Siraitia grosvenorii is known in China as a functional food product with the ability to improve lung function. Mogroside V is a triterpene glycoside isolated from S. grosvenorii. Nonetheless, the antiasthmatic effect of mogroside V has not been evaluat …
Siraitia grosvenorii is known in China as a functional food product with the ability to improve lung function. Mogroside V is …
Anti-depression-like effect of Mogroside V is related to the inhibition of inflammatory and oxidative stress pathways.
Liu H, Du Y, Liu LL, Liu QS, Mao HH, Cheng Y. Liu H, et al. Eur J Pharmacol. 2023 Sep 15;955:175828. doi: 10.1016/j.ejphar.2023.175828. Epub 2023 Jun 25. Eur J Pharmacol. 2023. PMID: 37364672
Siraitia grosvenorii (SG) is an edible medicinal plant found mainly in Guangxi, China, and Mogroside V (MGV) is the main component of SG extract. Previous research has shown that SG and MGV exert anti-inflammatory, antioxidative and neuroprotective effects. ...
Siraitia grosvenorii (SG) is an edible medicinal plant found mainly in Guangxi, China, and Mogroside V (MGV) is the main compo …
The pharmacokinetic profiles of mogrosides in T2DM rats.
Zhang Y, Peng Y, Zhou G, Li X. Zhang Y, et al. J Ethnopharmacol. 2022 Jan 10;282:114639. doi: 10.1016/j.jep.2021.114639. Epub 2021 Sep 14. J Ethnopharmacol. 2022. PMID: 34530093
STUDY DESIGN AND METHODS: High-fat diet and streptozocin induced type 2 diabetic mellitus rats were used to investigate the pharmacokinetic behavior of mogroside V and mogrosides IIIA(1), IIA(1), and IA(1) after T2DM rats orally administrated with mogroside
STUDY DESIGN AND METHODS: High-fat diet and streptozocin induced type 2 diabetic mellitus rats were used to investigate the pharmacokinetic …
Impact of acute consumption of beverages containing plant-based or alternative sweetener blends on postprandial appetite, food intake, metabolism, and gastro-intestinal symptoms: Results of the SWEET beverages trial.
Almiron-Roig E, Navas-Carretero S, Castelnuovo G, Kjølbæk L, Romo-Hualde A, Normand M, Maloney N, Hardman CA, Hodgkins CE, Moshoyiannis H, Finlayson G, Scott C, Raats MM, Harrold JA, Raben A, Halford JCG, Martínez JA. Almiron-Roig E, et al. Appetite. 2023 May 1;184:106515. doi: 10.1016/j.appet.2023.106515. Epub 2023 Feb 26. Appetite. 2023. PMID: 36849009 Free article. Clinical Trial.
The Beverages trial was a double-blind multi-centre, randomised crossover trial within SWEET evaluating the acute impact of three S&SE blends (plant-based and alternatives) vs. a sucrose control on glycaemic response, food intake, appetite sensations and safety after a carboh …
The Beverages trial was a double-blind multi-centre, randomised crossover trial within SWEET evaluating the acute impact of three S&SE b …
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