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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 1
1946 2
1947 11
1948 8
1949 4
1950 6
1951 4
1952 7
1953 4
1954 5
1955 11
1956 6
1957 9
1958 5
1959 5
1960 3
1961 4
1962 5
1963 7
1964 31
1965 12
1966 14
1967 22
1968 25
1969 30
1970 17
1971 28
1972 18
1973 33
1974 28
1975 45
1976 36
1977 33
1978 27
1979 29
1980 30
1981 27
1982 31
1983 35
1984 30
1985 28
1986 34
1987 26
1988 26
1989 49
1990 40
1991 36
1992 39
1993 52
1994 57
1995 32
1996 43
1997 22
1998 41
1999 34
2000 42
2001 40
2002 27
2003 24
2004 15
2005 22
2006 24
2007 37
2008 50
2009 41
2010 53
2011 48
2012 48
2013 51
2014 44
2015 36
2016 37
2017 46
2018 47
2019 56
2020 63
2021 57
2022 75
2023 72
2024 23

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2,206 results

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Page 1
Methenamine hippurate compared with antibiotic prophylaxis to prevent recurrent urinary tract infections in women: the ALTAR non-inferiority RCT.
Harding C, Chadwick T, Homer T, Lecouturier J, Mossop H, Carnell S, King W, Abouhajar A, Vale L, Watson G, Forbes R, Currer S, Pickard R, Eardley I, Pearce I, Thiruchelvam N, Guerrero K, Walton K, Hussain Z, Lazarowicz H, Ali A. Harding C, et al. Health Technol Assess. 2022 May;26(23):1-172. doi: 10.3310/QOIZ6538. Health Technol Assess. 2022. PMID: 35535708 Free article. Clinical Trial.
Emerging antimicrobial resistance is a global health concern, prompting research interest in non-antibiotic agents such as methenamine hippurate, but comparative data on their efficacy and safety are lacking. ...They were divided equally into two groups; half of the women …
Emerging antimicrobial resistance is a global health concern, prompting research interest in non-antibiotic agents such as methenamine …
Methenamine's journey of 160 years: Repurposal of an old urinary antiseptic for treatment and hypoxic radiosensitization of cancers and glioblastoma.
Altinoz MA, Ozpinar A, Ozpinar A, Perez JL, Elmaci İ. Altinoz MA, et al. Clin Exp Pharmacol Physiol. 2019 May;46(5):407-412. doi: 10.1111/1440-1681.13070. Epub 2019 Feb 27. Clin Exp Pharmacol Physiol. 2019. PMID: 30721527 Review.
In acidic conditions, methenamine decomposes to formaldehyde and ammonia. Recently, methenamine has gained a renewal of interest due to antibiotic-resistant bacteria urinary tract infections; interestingly, bacteria cannot gain resistance to formaldehyde. In 1968, D …
In acidic conditions, methenamine decomposes to formaldehyde and ammonia. Recently, methenamine has gained a renewal of intere …
Methenamine hippurate for preventing urinary tract infections.
Lee BS, Bhuta T, Simpson JM, Craig JC. Lee BS, et al. Cochrane Database Syst Rev. 2012 Oct 17;10(10):CD003265. doi: 10.1002/14651858.CD003265.pub3. Cochrane Database Syst Rev. 2012. PMID: 23076896 Free PMC article. Review.
BACKGROUND: Methenamine salts are often used as an alternative to antibiotics for the prevention of urinary tract infection (UTI). ...Manufacturers' of methenamine salts were contacted for unpublished studies and contact was made with known investigators.Date of las …
BACKGROUND: Methenamine salts are often used as an alternative to antibiotics for the prevention of urinary tract infection (UTI). .. …
Methenamine: a forgotten drug for preventing recurrent urinary tract infection in a multidrug resistance era.
Lo TS, Hammer KD, Zegarra M, Cho WC. Lo TS, et al. Expert Rev Anti Infect Ther. 2014 May;12(5):549-54. doi: 10.1586/14787210.2014.904202. Epub 2014 Apr 1. Expert Rev Anti Infect Ther. 2014. PMID: 24689705 Review.
Methenamine, a urinary antibacterial agent, can be used as methenamine hippurate or methenamine mandelate preparations and is United States Food and Drug Administration-approved. This article discusses the place of preventive therapy for recurrent UTIs, chemi …
Methenamine, a urinary antibacterial agent, can be used as methenamine hippurate or methenamine mandelate preparations …
Methenamine for Recurrent Urinary Tract Infections in Solid Organ Transplantation.
Sweiss H, Bhayana S, Hall R, Nelson J, Kincaide E. Sweiss H, et al. Prog Transplant. 2022 Mar;32(1):67-72. doi: 10.1177/15269248211064880. Epub 2021 Dec 3. Prog Transplant. 2022. PMID: 34859711
DESIGN: This retrospective review included patients > 18 years of age who received a kidney or liver-kidney transplant. Patients were divided into the following groups: (1) Methenamine therapy initiation received methenamine for 180 days or (2) Non-methenamine …
DESIGN: This retrospective review included patients > 18 years of age who received a kidney or liver-kidney transplant. Patients were div …
Nonantibiotic prevention and management of recurrent urinary tract infection.
Sihra N, Goodman A, Zakri R, Sahai A, Malde S. Sihra N, et al. Nat Rev Urol. 2018 Dec;15(12):750-776. doi: 10.1038/s41585-018-0106-x. Nat Rev Urol. 2018. PMID: 30361493 Review.
Potential nonantibiotic measures and treatments for UTIs include behavioural changes, dietary supplementation (such as Chinese herbal medicines and cranberry products), NSAIDs, probiotics, D-mannose, methenamine hippurate, estrogens, intravesical glycosaminoglycans, immuno …
Potential nonantibiotic measures and treatments for UTIs include behavioural changes, dietary supplementation (such as Chinese herbal medici …
Methenamine hippurate for preventing urinary tract infections.
Lee BB, Simpson JM, Craig JC, Bhuta T. Lee BB, et al. Cochrane Database Syst Rev. 2007 Oct 17;(4):CD003265. doi: 10.1002/14651858.CD003265.pub2. Cochrane Database Syst Rev. 2007. PMID: 17943785 Updated. Review.
BACKGROUND: Methenamine salts are often used as an alternative to antibiotics for the prevention of urinary tract infection (UTI). ...Manufacturers' of methenamine salts were contacted for unpublished studies and contact was made with known investigators. ...
BACKGROUND: Methenamine salts are often used as an alternative to antibiotics for the prevention of urinary tract infection (UTI). .. …
Methenamine hippurate for preventing urinary tract infections.
Lee B, Bhuta T, Craig J, Simpson J. Lee B, et al. Cochrane Database Syst Rev. 2002;(1):CD003265. doi: 10.1002/14651858.CD003265. Cochrane Database Syst Rev. 2002. PMID: 11869659 Updated. Review.
BACKGROUND: Methenamine salts are often used for the prevention of urinary tract infection (UTI). ...The manufacturers' of methenamine salts were contacted for unpublished studies and contact was made with known investigators in the area. ...
BACKGROUND: Methenamine salts are often used for the prevention of urinary tract infection (UTI). ...The manufacturers' of methena …
Drug therapy reviews: methenamine mandelate and methenamine hippurate.
Gleckman R, Alvarez S, Joubert DW, Matthews SJ. Gleckman R, et al. Am J Hosp Pharm. 1979 Nov;36(11):1509-12. Am J Hosp Pharm. 1979. PMID: 391033 Review.
The mechanism of action, spectrum of antimicrobial activity, pharmacokinetics, adverse effects, therapeutic use, and dosage of methenamine hippurate and methenamine mandelate are reviewed. The antimicrobial activity of methenamine depends on its conversion in …
The mechanism of action, spectrum of antimicrobial activity, pharmacokinetics, adverse effects, therapeutic use, and dosage of methenamin …
Alternative to prophylactic antibiotics for the treatment of recurrent urinary tract infections in women: multicentre, open label, randomised, non-inferiority trial.
Harding C, Mossop H, Homer T, Chadwick T, King W, Carnell S, Lecouturier J, Abouhajar A, Vale L, Watson G, Forbes R, Currer S, Pickard R, Eardley I, Pearce I, Thiruchelvam N, Guerrero K, Walton K, Hussain Z, Lazarowicz H, Ali A. Harding C, et al. BMJ. 2022 Mar 9;376:e068229. doi: 10.1136/bmj-2021-0068229. BMJ. 2022. PMID: 35264408 Free PMC article. Clinical Trial.
OBJECTIVE: To test and compare the efficacy of methenamine hippurate for prevention of recurrent urinary tract infections with the current standard prophylaxis of daily low dose antibiotics. ...RESULTS: Participants were randomly assigned to antibiotic prophylaxis (n=120) …
OBJECTIVE: To test and compare the efficacy of methenamine hippurate for prevention of recurrent urinary tract infections with the cu …
2,206 results