Abstract
The peptide H-Lys-Val-Leu-Asp-OH (KVLD), derived from antiflammins, and its analog H-Lys-Val-Asp-Leu-OH (KVDL) were prepared by solution synthesis. KVLD does not inhibit platelet aggregation in contrast to the results recently published.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Chemical Phenomena
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Chemistry, Physical
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Fibrinogen / metabolism
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Humans
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In Vitro Techniques
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Molecular Sequence Data
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Oligopeptides / chemical synthesis*
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Oligopeptides / pharmacology
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Platelet Aggregation Inhibitors / chemical synthesis*
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Platelet Aggregation Inhibitors / pharmacology
Substances
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Oligopeptides
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Platelet Aggregation Inhibitors
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lysyl-valyl-leucyl-aspartic acid
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lysyl-valyl-aspartyl-leucine
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Fibrinogen