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1985 | 1 |
1986 | 1 |
2024 | 0 |
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Interference of enantiomers of lofexidine with alpha-adrenoceptors.
Arch Int Pharmacodyn Ther. 1985 Jan;273(1):18-32.
Arch Int Pharmacodyn Ther. 1985.
PMID: 2988468
Some alpha-adrenoceptor-mediated cardiovascular activities and alpha-adrenoceptor binding affinities for (+)- and (-)-lofexidine (Dexlofexidine and Levlofexidine) have been studied in comparison with racemic lofexidine. ...
Some alpha-adrenoceptor-mediated cardiovascular activities and alpha-adrenoceptor binding affinities for (+)- and (-)-lofexidine (Dexlofexid …
Two stereoisomeric imidazoline derivatives: synthesis and optical and alpha 2-adrenoceptor activities.
Biedermann J, León-Lomelí A, Borbe HO, Prop G.
Biedermann J, et al.
J Med Chem. 1986 Jul;29(7):1183-8. doi: 10.1021/jm00157a011.
J Med Chem. 1986.
PMID: 2879913
Two eight-step pathways for synthesizing the stereoisomeric compounds (-)-2-[1-(2,6-dichlorophenoxy)ethyl]-2-imidazoline hydrochloride ("levlofexidine" hydrochloride; (-)-lofexidine hydrochloride) and (+)-2-[1-(2,6-dichlorophenoxy)ethyl]-2-imidazoline hydrochloride ("dexlo …
Two eight-step pathways for synthesizing the stereoisomeric compounds (-)-2-[1-(2,6-dichlorophenoxy)ethyl]-2-imidazoline hydrochloride (" …
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