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Year | Number of Results |
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1992 | 2 |
1996 | 1 |
1999 | 1 |
2017 | 1 |
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Identification of Cyclic Depsipeptides and Their Dedicated Synthetase from Hapsidospora irregularis.
J Nat Prod. 2017 Feb 24;80(2):363-370. doi: 10.1021/acs.jnatprod.6b00808. Epub 2017 Jan 20.
J Nat Prod. 2017.
PMID: 28106998
Free PMC article.
Seven cyclic depsipeptides were isolated from Hapsidospora irregularis and structurally characterized as the calcium channel blocker leualacin and six new analogues based on the NMR and HRESIMS data. ...Through genome sequencing and targeted gene disruption, a noniterative …
Seven cyclic depsipeptides were isolated from Hapsidospora irregularis and structurally characterized as the calcium channel blocker leua …
Leualacin, a novel calcium blocker from Hapsidospora irregularis. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties.
Hamano K, Kinoshita M, Furuya K, Miyamoto M, Takamatsu Y, Hemmi A, Tanzawa K.
Hamano K, et al.
J Antibiot (Tokyo). 1992 Jun;45(6):899-905. doi: 10.7164/antibiotics.45.899.
J Antibiot (Tokyo). 1992.
PMID: 1500357
Free article.
A new calcium blocker, designated leualacin, has been isolated from Hapsidospora irregularis. The compound inhibits the binding of 3H-nitrendipine, a well known synthetic calcium blocker, to cardiac Ca channel in a competitive manner, although its structure is completely d …
A new calcium blocker, designated leualacin, has been isolated from Hapsidospora irregularis. The compound inhibits the binding of 3H …
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Leualacin, a novel calcium blocker from Hapsidospora irregularis. II. Structure determination.
Hamano K, Kinoshita M, Tanzawa K, Yoda K, Ohki Y, Nakamura T, Kinoshita T.
Hamano K, et al.
J Antibiot (Tokyo). 1992 Jun;45(6):906-13. doi: 10.7164/antibiotics.45.906.
J Antibiot (Tokyo). 1992.
PMID: 1500358
Free article.
No abstract available.
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Synthesis and evaluation of backbone/amide-modified analogs of leualacin.
Hu MK, Yang FC, Chou CC, Yen MH.
Hu MK, et al.
Bioorg Med Chem Lett. 1999 Feb 22;9(4):563-8. doi: 10.1016/s0960-894x(99)00038-4.
Bioorg Med Chem Lett. 1999.
PMID: 10098664
Leualacin (1), a cyclic depsi-pentapeptide, and its backbone/amide-modified analogs 2-4 were synthesized. ...
Leualacin (1), a cyclic depsi-pentapeptide, and its backbone/amide-modified analogs 2-4 were synthesized. ...
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Total Synthesis of the Cyclic Depsipeptide Leualacin.
McLaren KL.
McLaren KL.
J Org Chem. 1996 Apr 19;61(8):2914. doi: 10.1021/jo964003z.
J Org Chem. 1996.
PMID: 11667139
No abstract available.
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