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Mutation induction and mutation spectra of S. typhimurium TA100 after exposure to isohistidines.
Zöhrer E, Albertini S, Gocke E, Knasmüller S. Zöhrer E, et al. Mutat Res. 1996 Sep 23;356(2):155-61. doi: 10.1016/0027-5107(96)00034-6. Mutat Res. 1996. PMID: 8841480
L-Isohistidine and D,L-isohistidine, but not D-isohistidine, caused an increase of the number of mutant colonies in S. typhimurium strain TA100. Spontaneous and also sodium azide or 2-aminoanthracene induced mutant numbers were enhanced by L …
L-Isohistidine and D,L-isohistidine, but not D-isohistidine, caused an increase of the number of mutant c …
Synthesis of Nβ-Substituted α,β-Diamino Acids via Stereoselective N-Michael Additions to a Chiral Bicyclic Dehydroalanine.
Navo CD, Mazo N, Oroz P, Gutiérrez-Jiménez MI, Marín J, Asenjo J, Avenoza A, Busto JH, Corzana F, Zurbano MM, Jiménez-Osés G, Peregrina JM. Navo CD, et al. J Org Chem. 2020 Mar 6;85(5):3134-3145. doi: 10.1021/acs.joc.9b03020. Epub 2020 Feb 19. J Org Chem. 2020. PMID: 32040912
This procedure offers an efficient and practical approach for the synthesis of N(beta)-substituted alpha,beta-diamino acids, such as 1-isohistidine, tau-histidinoalanine, beta-benzylaminoalanine, beta-(piperidin-1-yl)alanine, beta-(azepan-1-yl)alanine, and fluorescent and …
This procedure offers an efficient and practical approach for the synthesis of N(beta)-substituted alpha,beta-diamino acids, such as 1-is …
Renin inhibitors as an example of presumptive irrelevant positive findings in the Salmonella/mammalian microsome assay (Ames test).
Albertini S, Gocke E. Albertini S, et al. Mutat Res. 1993 Feb;298(4):237-46. doi: 10.1016/0165-1218(93)90002-u. Mutat Res. 1993. PMID: 7678159
Analogous effects were previously shown for free histidine, isohistidine, phenobarbital and tetracycline and in part explained by molecular mechanisms....
Analogous effects were previously shown for free histidine, isohistidine, phenobarbital and tetracycline and in part explained by mol …
1-amino-2-imidazol-4'-ylethylphosphonic acid is a potent reversible inhibitor of Pseudomonas putida histidine ammonia-lyase.
Hernández D, Phillips AT, Zoń J. Hernández D, et al. Biochem Mol Biol Int. 1994 Jan;32(1):189-94. Biochem Mol Biol Int. 1994. PMID: 8012285
A twenty-fold molar excess of HisP over enzyme completely protected the active site of histidase from inactivation by 10 mM bisulfite. Neither isohistidine nor two other phosphonic acid compounds were inhibitory towards histidase when tested at 1 mM concentration....
A twenty-fold molar excess of HisP over enzyme completely protected the active site of histidase from inactivation by 10 mM bisulfite. Neith …
Histidine analogues as potential novel antirheumatic agents.
Roberts NA, Tong BP. Roberts NA, et al. Drug Des Deliv. 1986 Nov;1(2):113-8. Drug Des Deliv. 1986. PMID: 3151240
Within the series of histidine analogues, relationships between structure and activity were determined, isohistidine (alpha-amino-2-imidazolepropionic acid) and some of its simple derivatives being particularly active....
Within the series of histidine analogues, relationships between structure and activity were determined, isohistidine (alpha-amino-2-i …