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1982 1
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33 results

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Page 1
Effects of a defective endoplasmic reticulum-associated degradation pathway on the stress response, virulence, and antifungal drug susceptibility of the mold pathogen Aspergillus fumigatus.
Krishnan K, Feng X, Powers-Fletcher MV, Bick G, Richie DL, Woollett LA, Askew DS. Krishnan K, et al. Eukaryot Cell. 2013 Apr;12(4):512-9. doi: 10.1128/EC.00319-12. Epub 2013 Jan 25. Eukaryot Cell. 2013. PMID: 23355008 Free PMC article.
An imbalance between the level of nascent proteins entering the ER and the organelle's ability to manage that load results in the accumulation of unfolded proteins. ...Loss of HrdA was associated with impaired degradation of a folding-defective ERAD substrate …
An imbalance between the level of nascent proteins entering the ER and the organelle's ability to manage that load results in the acc …
Cellular responses to the expression of unstable secretory proteins in the filamentous fungus Aspergillus oryzae.
Yokota JI, Shiro D, Tanaka M, Onozaki Y, Mizutani O, Kakizono D, Ichinose S, Shintani T, Gomi K, Shintani T. Yokota JI, et al. Appl Microbiol Biotechnol. 2017 Mar;101(6):2437-2446. doi: 10.1007/s00253-016-8086-3. Epub 2017 Jan 7. Appl Microbiol Biotechnol. 2017. PMID: 28064367
However, even using strong transcriptional promoters, yields of nonfungal proteins are generally much lower than those of fungal proteins. Recent analyses revealed that expression of certain nonfungal secretory proteins induced the unfolded protein res …
However, even using strong transcriptional promoters, yields of nonfungal proteins are generally much lower than those of fungal p
Construction and characterization of Streptomyces coelicolor A3(2) mutants that are multiply deficient in the nonessential hrd-encoded RNA polymerase sigma factors.
Buttner MJ, Lewis CG. Buttner MJ, et al. J Bacteriol. 1992 Aug;174(15):5165-7. doi: 10.1128/jb.174.15.5165-5167.1992. J Bacteriol. 1992. PMID: 1629177 Free PMC article.
Previous studies showed that Streptomyces coelicolor A3(2) has four genes (hrdA, hrdB, hrdC, and hrdD) that appear to encode RNA polymerase sigma factors very similar to the sigma 70 subunit of Escherichia coli and that hrdC and hrdD could be individually disrupted without …
Previous studies showed that Streptomyces coelicolor A3(2) has four genes (hrdA, hrdB, hrdC, and hrdD) that appear to encode RNA poly …
Mutagenic analysis of the promoter of the Streptomyces fradiae beta-lactamase-encoding gene.
Forsman M, Granström M. Forsman M, et al. Gene. 1992 Nov 2;121(1):87-94. doi: 10.1016/0378-1119(92)90165-l. Gene. 1992. PMID: 1385267
PblaF was shown not to be recognized by sigma-whiG or by sigma-hrdA, hrdC, or hrdD. Sequence alignment of PblaF to sigma factor-classified Streptomyces promoters revealed little homology. ...
PblaF was shown not to be recognized by sigma-whiG or by sigma-hrdA, hrdC, or hrdD. Sequence alignment of PblaF to sigma factor-class …
Differential expression of principal sigma factor homologues of Streptomyces aureofaciens correlates with the developmental stage.
Kormanec J, Farkasovský M. Kormanec J, et al. Nucleic Acids Res. 1993 Aug 11;21(16):3647-52. doi: 10.1093/nar/21.16.3647. Nucleic Acids Res. 1993. PMID: 8367281 Free PMC article.
In previous experiments, Streptomyces aureofaciens has been shown to contain four genes hrdA, hrdB, hrdD, and hrdE, encoding polypeptides very similar to principal sigma factors of RNA polymerase. Two apparent tandem promoters were identified for each of the hrdA, h …
In previous experiments, Streptomyces aureofaciens has been shown to contain four genes hrdA, hrdB, hrdD, and hrdE, encoding polypept …
Stress-activated expression of a Streptomyces pristinaespiralis multidrug resistance gene (ptr) in various Streptomyces spp. and Escherichia coli.
Salah-Bey K, Blanc V, Thompson CJ. Salah-Bey K, et al. Mol Microbiol. 1995 Sep;17(5):1001-12. doi: 10.1111/j.1365-2958.1995.mmi_17051001.x. Mol Microbiol. 1995. PMID: 8596428
In Streptomyces coelicolor, Pptr activity was similarly inducible by PI and not dependent on sigma factors HrdA, HrdC, or HrdD. In E. coli, Pptr cloned in the bifunctional promoter probe vector pIJ2839 was functional and activated upon entry into stationary phase in the ab …
In Streptomyces coelicolor, Pptr activity was similarly inducible by PI and not dependent on sigma factors HrdA, HrdC, or HrdD. In E. …
Identification of multiple RNA polymerase sigma factor homologs in the cyanobacterium Anabaena sp. strain PCC 7120: cloning, expression, and inactivation of the sigB and sigC genes.
Brahamsha B, Haselkorn R. Brahamsha B, et al. J Bacteriol. 1992 Nov;174(22):7273-82. doi: 10.1128/jb.174.22.7273-7282.1992. J Bacteriol. 1992. PMID: 1385387 Free PMC article.
Takahashi, Science 242:1040-1042, 1988) were used as probes to isolate two genes, sigB and sigC, which encode two putative sigma factors exhibiting high degrees of similarity to SigA, to HrdA, -B, -C, and -D of Streptomyces coelicolor, and to KatF of Escherichia coli. sigB …
Takahashi, Science 242:1040-1042, 1988) were used as probes to isolate two genes, sigB and sigC, which encode two putative sigma factors exh …
Mitochondrial Genome of Prasinophyte Alga Pyramimonas parkeae.
Hrdá Š, Hroudová M, Vlček Č, Hampl V. Hrdá Š, et al. J Eukaryot Microbiol. 2017 May;64(3):360-369. doi: 10.1111/jeu.12371. Epub 2016 Oct 24. J Eukaryot Microbiol. 2017. PMID: 27678215
The phylogenetic analysis using the data set of 6,037 positions assembled from 34 mtDNA-encoded proteins of 48 green algae and plants is not in compliance with the branching order of prasinophyte clades revealed on the basis of 18S rRNA genes and cpDNA-encoded proteins
The phylogenetic analysis using the data set of 6,037 positions assembled from 34 mtDNA-encoded proteins of 48 green algae and plants …
Nucleotide sequence of genes hrdA, hrdC, and hrdD from Streptomyces coelicolor A3(2) having similarity to rpoD genes.
Tanaka K, Shiina T, Takahashi H. Tanaka K, et al. Mol Gen Genet. 1991 Oct;229(3):334-40. doi: 10.1007/BF00267453. Mol Gen Genet. 1991. PMID: 1944221
The complete nucleotide sequences were determined of hrdA, hrdC, and hrdD from Streptomyces coelicolor A3(2). They indicate the presence of a single open reading frame in each gene coding for polypeptides of 396 (43,747 daltons), 339 (38,173 daltons), and 332 amino acid re …
The complete nucleotide sequences were determined of hrdA, hrdC, and hrdD from Streptomyces coelicolor A3(2). They indicate the prese …
Four genes in Streptomyces aureofaciens containing a domain characteristic of principal sigma factors.
Kormanec J, Farkasovský M, Potúcková L. Kormanec J, et al. Gene. 1992 Dec 1;122(1):63-70. doi: 10.1016/0378-1119(92)90032-k. Gene. 1992. PMID: 1452038
Four genes encoding sigma-factor-like proteins, hrdA, hrdB, hrdD, and hrdE, were identified in a Streptomyces aureofaciens genomic library using an oligodeoxyribonucleotide probe encoding a peptide motif homologous to the core-binding domain in sigma factors. The de …
Four genes encoding sigma-factor-like proteins, hrdA, hrdB, hrdD, and hrdE, were identified in a Streptomyces aureofaciens gen …
33 results