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1977 1
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Page 1
Optimization of a microarray for fission yeast.
Kim DU, Lee M, Han S, Nam M, Lee S, Lee J, Woo J, Kim D, Hoe KL. Kim DU, et al. Genomics Inform. 2019 Sep;17(3):e28. doi: 10.5808/GI.2019.17.3.e28. Epub 2019 Sep 18. Genomics Inform. 2019. PMID: 31610624 Free PMC article.
Activation of frozen pooled cells for >1 day showed better resolution of intensity than no activation. A tag intensity analysis showed that tag(s) of 4,316 of the 4,526 strains tested were represented at least once; 3,706 strains were represented by both tags, 4,072 str …
Activation of frozen pooled cells for >1 day showed better resolution of intensity than no activation. A tag intensity analysis showed th …
HOE-234, a second generation K+ channel opener, antagonizes the ATP-dependent gating of cardiac ATP-sensitive K+ channels.
Terzic A, Jahangir A, Kurachi Y. Terzic A, et al. J Pharmacol Exp Ther. 1994 Feb;268(2):818-25. J Pharmacol Exp Ther. 1994. PMID: 8113994
In the absence of HOE-234, half-inhibition of spontaneously operative KATP channels occurred at 25 microM of intracellular ATP (ATPi), whereas in the presence of HOE-234 (10 microM), 316 microM of ATPi was required for half-inhibition. ...After run-down, the …
In the absence of HOE-234, half-inhibition of spontaneously operative KATP channels occurred at 25 microM of intracellular ATP (ATPi) …
Effects of Hoe-140 and ramiprilat on arteriolar tone and dilation to bradykinin in skeletal muscle of rats.
Koller A, Rodenburg JM, Kaley G. Koller A, et al. Am J Physiol. 1995 Apr;268(4 Pt 2):H1628-33. doi: 10.1152/ajpheart.1995.268.4.H1628. Am J Physiol. 1995. PMID: 7733364
All agonists were administered topically on the exteriorized muscle. With use of Hoe-140, a B2-receptor antagonist, the presence of kinin receptors in arterioles was studied. ...Also, whereas Hoe-140 significantly reduced basal arteriolar diameters (from 16.7 +/- 0. …
All agonists were administered topically on the exteriorized muscle. With use of Hoe-140, a B2-receptor antagonist, the presence of k …
Blockade of hippocampal bradykinin B1 receptors improves spatial learning and memory deficits in middle-aged rats.
Bitencourt RM, Guerra de Souza AC, Bicca MA, Pamplona FA, de Mello N, Passos GF, Medeiros R, Takahashi RN, Calixto JB, Prediger RD. Bitencourt RM, et al. Behav Brain Res. 2017 Jan 1;316:74-81. doi: 10.1016/j.bbr.2016.08.041. Epub 2016 Aug 24. Behav Brain Res. 2017. PMID: 27566183
A single intra-hippocampal injection of the selective B(1)R antagonist des-Arg(9)-[Leu(8)]-bradykinin (DALBK, 3 nmol), but not the selective B(2)R antagonist D-Arg-[Hyp(3),Thi(5),D-Tic(7),Oic(8)]-BK (Hoe 140, 3 nmol), reversed the spatial learning and memory deficits on th …
A single intra-hippocampal injection of the selective B(1)R antagonist des-Arg(9)-[Leu(8)]-bradykinin (DALBK, 3 nmol), but not the selective …
Antioedematogenic and antinociceptive actions of NPC 18521, a novel bradykinin B2 receptor antagonist.
De Campos RO, Alves RV, Kyle DJ, Chakravarty S, Mavunkel BJ, Calixto JB. De Campos RO, et al. Eur J Pharmacol. 1996 Dec 5;316(2-3):277-86. doi: 10.1016/s0014-2999(96)00661-9. Eur J Pharmacol. 1996. PMID: 8982699
This effect was almost completely blocked by cyproheptadine (20 mg/kg, i.p.) or by compound 48/80 (12 micrograms/paw), but was unaffected by Hoe 140 (D-Arg-[Hyp5,Thi5,Tic7,Oic8]bradykinin). NPC 18521 (0.3-10 nmol/kg, i.p.) produced significant inhibition of acetic acid, ac …
This effect was almost completely blocked by cyproheptadine (20 mg/kg, i.p.) or by compound 48/80 (12 micrograms/paw), but was unaffected by …
Na(+)/H(+) exchanger inhibitor HOE642 offers myoprotection in senescent myocardium independent of ischemic preconditioning mechanisms.
Nakai Y, Horimoto H, Mieno S, Sasaki S. Nakai Y, et al. Eur Surg Res. 2002 May-Jun;34(3):244-50. doi: 10.1159/000063396. Eur Surg Res. 2002. PMID: 12077512

RESULTS: (1) In the mature hearts, HOE642 improved postischemic functional recovery (63.1 +/- 5.0% vs. 84.4 +/- 5.4%, mature untreated vs. mature HOE, p < 0.05) and reduced infarct size as compared to untreated hearts (42.0 +/- 2.5% vs. 24.8 +/- 2.3%, mature untreated v

…
RESULTS: (1) In the mature hearts, HOE642 improved postischemic functional recovery (63.1 +/- 5.0% vs. 84.4 +/- 5.4%, mature untreated vs. m …
1,4-Bis-[1-methyl-5-nitroimidazolyl-(2-methyleneimino)]-piperazine, a new drug with marked activity against Entamoeba histolytica. Short communication.
Raether W, Seidenath H, Winkelmann E. Raether W, et al. Arzneimittelforschung. 1977;27(5):968-9. Arzneimittelforschung. 1977. PMID: 195590
1,4-Bis-[1-methyl-5-nitroimidazolyl-(2-methyleneimino)]-piperazine (HOE 316) administered orally produces an effect which is clearly superior to that of metronidazole against Entamoeba histolytica in the golden hamster and slightly inferior against Trichomonas fetus …
1,4-Bis-[1-methyl-5-nitroimidazolyl-(2-methyleneimino)]-piperazine (HOE 316) administered orally produces an effect which is c …