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A new immunomodulator, FR-901235.
Shibata T, Nishikawa M, Tsurumi Y, Takase S, Terano H, Kohsaka M. Shibata T, et al. J Antibiot (Tokyo). 1989 Sep;42(9):1356-61. doi: 10.7164/antibiotics.42.1356. J Antibiot (Tokyo). 1989. PMID: 2793590 Free article.
FR-901235 is a new type of immunoactive substance produced by an imperfect fungus, Paecilomyces carneus F-4882. The mitogen-induced lymphocyte proliferation which had been suppressed by addition of immunosuppressive factor, was restored to a normal level by the addi …
FR-901235 is a new type of immunoactive substance produced by an imperfect fungus, Paecilomyces carneus F-4882. The mitogen-in …
Total Syntheses of FR-901235, Auxarthrones A-D, and Lamellicolic Anhydride.
Kiyotaki K, Kayukawa T, Imayoshi A, Tsubaki K. Kiyotaki K, et al. Org Lett. 2020 Dec 4;22(23):9220-9224. doi: 10.1021/acs.orglett.0c03401. Epub 2020 Nov 16. Org Lett. 2020. PMID: 33196202
Using the rearrangement as a key reaction, the first total syntheses of FR-901235 and auxarthrones A-D from an unstable triketone common intermediate are described. ...
Using the rearrangement as a key reaction, the first total syntheses of FR-901235 and auxarthrones A-D from an unstable triket …
Polyketides from Penicillium sp. JP-1, an endophytic fungus associated with the mangrove plant Aegiceras corniculatum.
Lin Z, Zhu T, Fang Y, Gu Q, Zhu W. Lin Z, et al. Phytochemistry. 2008 Mar;69(5):1273-8. doi: 10.1016/j.phytochem.2007.10.030. Epub 2007 Dec 11. Phytochemistry. 2008. PMID: 18067932
Four polyketides, leptosphaerone C (1), penicillenone (2), arugosin I (3) and 9-demethyl FR-901235 (4), as well as five known compounds, bacillosporin A (5), bacillosporin C (6), sequoiamonascin D (7), sequoiatone A (8), and sequoiatone B (9) were isolated from the …
Four polyketides, leptosphaerone C (1), penicillenone (2), arugosin I (3) and 9-demethyl FR-901235 (4), as well as five known …