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RIFM fragrance ingredient safety assessment, 3-heptanone, CAS Registry Number 106-35-4.
Api AM, Belsito D, Botelho D, Bruze M, Burton GA Jr, Buschmann J, Dagli ML, Date M, Dekant W, Deodhar C, Francis M, Fryer AD, Jones L, Joshi K, La Cava S, Lapczynski A, Liebler DC, O'Brien D, Patel A, Penning TM, Ritacco G, Romine J, Sadekar N, Salvito D, Schultz TW, Sipes IG, Sullivan G, Thakkar Y, Tokura Y, Tsang S. Api AM, et al. Food Chem Toxicol. 2019 Aug;130 Suppl 1:110452. doi: 10.1016/j.fct.2019.04.022. Epub 2019 Apr 21. Food Chem Toxicol. 2019. PMID: 31018147 Review. No abstract available.
RIFM fragrance ingredient safety assessment, 5-methyl-3-heptanone, CAS Registry Number 541-85-5.
Api AM, Belsito D, Botelho D, Bruze M, Burton GA Jr, Buschmann J, Dagli ML, Date M, Dekant W, Deodhar C, Francis M, Fryer AD, Jones L, Joshi K, La Cava S, Lapczynski A, Liebler DC, O'Brien D, Patel A, Penning TM, Ritacco G, Romine J, Sadekar N, Salvito D, Schultz TW, Sipes IG, Sullivan G, Thakkar Y, Tokura Y, Tsang S. Api AM, et al. Food Chem Toxicol. 2020 Apr 15;138 Suppl 1:111273. doi: 10.1016/j.fct.2020.111273. Epub 2020 Mar 18. Food Chem Toxicol. 2020. PMID: 32199970 Review. No abstract available.
Further studies on ketone neurotoxicity and interactions.
O'Donoghue JL, Krasavage WJ, DiVincenzo GD, Katz GV. O'Donoghue JL, et al. Toxicol Appl Pharmacol. 1984 Feb;72(2):201-9. doi: 10.1016/0041-008x(84)90304-1. Toxicol Appl Pharmacol. 1984. PMID: 6546457
Ethyl n-butyl ketone (EBK, 3-heptanone) has not been reported to produce neurotoxicity in previous studies when it was given by oral or inhalation routes. ...
Ethyl n-butyl ketone (EBK, 3-heptanone) has not been reported to produce neurotoxicity in previous studies when …
A new passive sampler for regulated workplace ketones.
Tsai SW, Hee SS. Tsai SW, et al. AIHAJ. 2000 Nov-Dec;61(6):808-14. doi: 10.1080/15298660008984590. AIHAJ. 2000. PMID: 11192212
The experimental passive sampler sampling rates in milliliters per minute at 25 degrees C were 4.07 +/- 0.49, cyclohexanone; 6.30 +/- 0.59, diethyl ketone; 6.31 +/- 0.31, ethyl n-butyl ketone; 3.78 +/- 0.25, methyl n-amyl ketone; 3.43 +/- 0.19, methyl …
The experimental passive sampler sampling rates in milliliters per minute at 25 degrees C were 4.07 +/- 0.49, cyclohexanone; 6.30 +/- 0.59, …