Effects of automated external lubrication on tablet properties and the stability of eprazinone hydrochloride.
Yamamura T, Ohta T, Taira T, Ogawa Y, Sakai Y, Moribe K, Yamamoto K.
Yamamura T, et al.
Int J Pharm. 2009 Mar 31;370(1-2):1-7. doi: 10.1016/j.ijpharm.2008.11.007. Epub 2008 Nov 18.
Int J Pharm. 2009.
PMID: 19059327
The resulting tablets were compared with tablets produced by the conventional internal lubrication method, in which lubricant is blended before tableting. As a model API, we chose eprazinone hydrochloride, because it is easily hydrolyzed by alkaline lubricant. ...External …
The resulting tablets were compared with tablets produced by the conventional internal lubrication method, in which lubricant is blended bef …