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Comparison of Antioxidant and Anticancer Properties of Soft Coral-Derived Sinularin and Dihydrosinularin.
Wang SC, Li RN, Lin LC, Tang JY, Su JH, Sheu JH, Chang HW. Wang SC, et al. Molecules. 2021 Jun 24;26(13):3853. doi: 10.3390/molecules26133853. Molecules. 2021. PMID: 34202721 Free PMC article.
Sinularin and dihydrosinularin also show an induction for Fe(+3)-reduction and Fe(+2)-chelating capacity which both strengthen their antioxidant activities. Importantly, sinularin shows higher antioxidant properties than dihydrosinularin. Moreover, 24 h ATP assays s …
Sinularin and dihydrosinularin also show an induction for Fe(+3)-reduction and Fe(+2)-chelating capacity which both strengthen their …
Soft Coral-Derived Dihydrosinularin Exhibits Antiproliferative Effects Associated with Apoptosis and DNA Damage in Oral Cancer Cells.
Yang KH, Lin YS, Wang SC, Lee MY, Tang JY, Chang FR, Chuang YT, Sheu JH, Chang HW. Yang KH, et al. Pharmaceuticals (Basel). 2021 Sep 29;14(10):994. doi: 10.3390/ph14100994. Pharmaceuticals (Basel). 2021. PMID: 34681218 Free PMC article.
Dihydrosinularin (DHS) is an analog of soft coral-derived sinularin; however, the anticancer effects and mechanisms of DHS have seldom been reported. ...
Dihydrosinularin (DHS) is an analog of soft coral-derived sinularin; however, the anticancer effects and mechanisms of DHS have seldo …
Isolation of the cembranolide diterpenes dihydrosinularin and 11-epi-sinulariolide from the marine mollusk Planaxis sulcatus.
Sanduja R, Sanduja SK, Weinheimer AJ, Alam M, Martin GE. Sanduja R, et al. J Nat Prod. 1986 Jul-Aug;49(4):718-9. doi: 10.1021/np50046a038. J Nat Prod. 1986. PMID: 3783170
Dihydrosinularin and 11-epi-sinulariolide acetate have been isolated previously from soft corals which, together with gorgonians, are the richest sources of marine cembranoids. ...It is expected these diterpenes are of dietary origin although the possibility of biotransfor …
Dihydrosinularin and 11-epi-sinulariolide acetate have been isolated previously from soft corals which, together with gorgonians, are …
New cembranolide analogues from the formosan soft coral Sinularia flexibilis and their cytotoxicity.
Hsieh PW, Chang FR, McPhail AT, Lee KH, Wu YC. Hsieh PW, et al. Nat Prod Res. 2003 Dec;17(6):409-18. doi: 10.1080/14786910310001617677. Nat Prod Res. 2003. PMID: 14577690
Using a bioactivity-guided fractionation procedure, five cembranolides, 11-epi-sinulariolide acetate (1), 11-dehydrosinulariolide (2), sinulariolide (3), dihydrosinularin (4), and 3,4:8,11-bisepoxy-7-acetoxycembra-15(17)-en-1,12-olide (5), along with two nucleosides, 2'-de …
Using a bioactivity-guided fractionation procedure, five cembranolides, 11-epi-sinulariolide acetate (1), 11-dehydrosinulariolide (2), sinul …