Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1983 3
1984 1
1985 3
1986 3
1987 12
1988 10
1989 9
1990 5
1991 9
1992 5
1993 3
1994 5
1995 2
1996 1
1997 1
2000 4
2001 2
2002 1
2005 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

80 results

Results by year

Filters applied: . Clear all
Page 1
Deltakephalin, Tyr-D-Thr-Gly-Phe-Leu-Thr: a new highly potent and fully specific agonist for opiate delta-receptors.
Zajac JM, Gacel G, Petit F, Dodey P, Rossignol P, Roques BP. Zajac JM, et al. Biochem Biophys Res Commun. 1983 Mar 16;111(2):390-7. doi: 10.1016/0006-291x(83)90318-2. Biochem Biophys Res Commun. 1983. PMID: 6301470
Deltakephalin, Tyr-D-Thr-Gly-Phe-Leu-Thr (DTLET) was rationally designed as pure delta-probe from proposed models of mu and delta opiate receptors. ...Deltakephalin occurs as the most specific ligand for delta-binding sites as shown by the following discrimination r …
Deltakephalin, Tyr-D-Thr-Gly-Phe-Leu-Thr (DTLET) was rationally designed as pure delta-probe from proposed models of mu and delta opi …
Opposite effects of delta and mu opioid receptor agonists on the in vitro release of substance P-like material from the rat spinal cord.
Mauborgne A, Lutz O, Legrand JC, Hamon M, Cesselin F. Mauborgne A, et al. J Neurochem. 1987 Feb;48(2):529-37. doi: 10.1111/j.1471-4159.1987.tb04125.x. J Neurochem. 1987. PMID: 2432185
Thus, the two preferential mu agonists Tyr-D-Ala-Gly-MePhe-Gly-ol (DAGO; 10 microM) and Tyr-D-Ala-Gly-MePhe-Met(O)5-OH (FK-33824; 0.1 microM) enhanced SPLI overflow from depolarized tissues, whereas the selective delta agonists Tyr-D-Thr-Gly-Phe-Leu-Thr (deltakephalin; 3 m …
Thus, the two preferential mu agonists Tyr-D-Ala-Gly-MePhe-Gly-ol (DAGO; 10 microM) and Tyr-D-Ala-Gly-MePhe-Met(O)5-OH (FK-33824; 0.1 microM …
Pain control by endogenous enkephalins is mediated by mu opioid receptors.
Chaillet P, Coulaud A, Fournié-Zaluski MC, Gacel G, Roques BP, Costentin J. Chaillet P, et al. Life Sci. 1983;33 Suppl 1:685-8. doi: 10.1016/0024-3205(83)90595-7. Life Sci. 1983. PMID: 6319920
The relative analgesic potency of DAGO and deltakephalin is in good agreement with their relative potency on mu pharmacological assays: inhibition of electrically-induced contractions of guinea-pig ileum, displacement of 3H DAGO on rat brain. Finally, the analgesic effects …
The relative analgesic potency of DAGO and deltakephalin is in good agreement with their relative potency on mu pharmacological assay …
Analgesic activity of morphiceptin, beta-casomorphin-4, and deltakephalin in normotensive Wistar-Glaxo and spontaneously hypertensive rats.
Widy-Tyszkiewicz E, Członkowski A. Widy-Tyszkiewicz E, et al. Peptides. 1989 May-Jun;10(3):539-44. doi: 10.1016/0196-9781(89)90139-3. Peptides. 1989. PMID: 2780414
The effects of intraventricular injection of beta-casomorphin-4, morphiceptin and deltakephalin (DTLET) on hot water tail flick and tail compression responses were investigated in Wistar Albino Glaxo (WAG) and spontaneously hypertensive rats (SHR). The effects of the mu ag …
The effects of intraventricular injection of beta-casomorphin-4, morphiceptin and deltakephalin (DTLET) on hot water tail flick and t …
Enkephalinase is involved in the degradation of endogenous substance P released from slices of rat substantia nigra.
Mauborgne A, Bourgoin S, Benoliel JJ, Hirsch M, Berthier JL, Hamon M, Cesselin F. Mauborgne A, et al. J Pharmacol Exp Ther. 1987 Nov;243(2):674-80. J Pharmacol Exp Ther. 1987. PMID: 2445957
In agreement with this interpretation, the direct stimulation of delta opiate receptors by deltakephalin was found to significantly reduce SPLI overflow. Furthermore, an increased outflow of [Met]enkephalin-like material was observed from substantia nigra slices superfused …
In agreement with this interpretation, the direct stimulation of delta opiate receptors by deltakephalin was found to significantly r …
Crystal structure of deltakephalin: a delta-selective opioid peptide with a novel beta-bend-like conformation.
Flippen-Anderson JL, Deschamps JR, Ward KB, George C, Houghten R. Flippen-Anderson JL, et al. Int J Pept Protein Res. 1994 Aug;44(2):97-104. doi: 10.1111/j.1399-3011.1994.tb00563.x. Int J Pept Protein Res. 1994. PMID: 7982763
The solid-state structure of deltakephalin (Tyr-DThr-Gly-Phe-Leu-Thr) has been determined by single-crystal X-ray diffraction. Deltakephalin (DTLET) is a synthetic opioid peptide which differs from enkephalin in that a D-Thr has been substituted for Gly2 and a sixth …
The solid-state structure of deltakephalin (Tyr-DThr-Gly-Phe-Leu-Thr) has been determined by single-crystal X-ray diffraction. Del …
80 results