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Page 1
A study on the reaction of 16-dehydropregnenolone acetate with 2-aminobenzimidazole.
Wojtkielewicz A, Uścinowicz P, Siergiejczyk L, Kiełczewska U, Ratkiewicz A, Morzycki JW. Wojtkielewicz A, et al. Steroids. 2017 Jan;117:71-76. doi: 10.1016/j.steroids.2016.09.003. Epub 2016 Sep 16. Steroids. 2017. PMID: 27644145
The condensation of 16-dehydropregnenolone acetate with 2-aminobenzimidazole was studied. The polycyclic aromatic product was formed as a single regioisomer in a cascade reaction comprising addition, cyclization, autoxidation, and aromatization, in addition to the r …
The condensation of 16-dehydropregnenolone acetate with 2-aminobenzimidazole was studied. The polycyclic aromatic product was …
Synthesis of steroidal 1,2- and 1,3-diamines as ligands for transition metal ion complexation.
Seroka B, Łotowski Z, Wojtkielewicz A, Bazydło P, Dudź E, Hryniewicka A, Morzycki JW. Seroka B, et al. Steroids. 2019 Jul;147:19-27. doi: 10.1016/j.steroids.2019.02.001. Epub 2019 Feb 6. Steroids. 2019. PMID: 30738072 Review.
Furthermore, the other two amines were synthesized from 16-dehydropregnenolone acetate using aza-Michael addition as a key step. Some of the diamines were subjected to complexation reactions with K(2)PtCl(4) to form steroidal analogs of cisplatin. ...
Furthermore, the other two amines were synthesized from 16-dehydropregnenolone acetate using aza-Michael addition as a key ste …
Bioconversion of 16-dehydropregnenolone Acetate to Exclusively 4-androstene-3,17-dione by Delftia acidovorans MTCC 3363.
Awadhiya P, Banerjee T, Patil S. Awadhiya P, et al. Pol J Microbiol. 2017 Sep 27;66(3):321-326. doi: 10.5604/01.3001.0010.4858. Pol J Microbiol. 2017. PMID: 29319524 Free article.
Delftia acidovorans MTCC 3363 was found to convert 16-dehydropregnenolone acetate (16-DPA) exclusively to 4-androstene-3, 17-dione (AD). ...
Delftia acidovorans MTCC 3363 was found to convert 16-dehydropregnenolone acetate (16-DPA) exclusively to 4-androstene-3, 17-d …
Synthesis and activity of novel 16-dehydropregnenolone acetate derivatives as inhibitors of type 1 5alpha-reductase and on cancer cell line SK-LU-1.
Silva-Ortiz AV, Bratoeff E, Ramírez-Apan T, Heuze Y, Sánchez A, Soriano J, Cabeza M. Silva-Ortiz AV, et al. Bioorg Med Chem. 2015 Dec 15;23(24):7535-42. doi: 10.1016/j.bmc.2015.10.047. Epub 2015 Nov 4. Bioorg Med Chem. 2015. PMID: 26631442
When this mechanism is altered, androgen-dependent diseases, including prostate cancer, could result. The aim of this study was to synthesize several 16-dehydropregnenolone acetate derivatives containing a triazole ring at C-21 and a linear or alicyclic ester moiety …
When this mechanism is altered, androgen-dependent diseases, including prostate cancer, could result. The aim of this study was to synthesiz …
An Efficient Procedure for the Synthesis of 21-Acetoxypregna-1,4,9(11),16- tetraene-3,20-dione.
Huy LD, Diep NT, Vu TK, Savinova TS, Donova MV. Huy LD, et al. Comb Chem High Throughput Screen. 2020;23(3):225-231. doi: 10.2174/1386207323666200219122644. Comb Chem High Throughput Screen. 2020. PMID: 32072895
Currently, industrial production is based on the chemical syntheses of corticosteroids from either 16- dehydropregnenolone acetate (obtained from diosgenin) or androstenedione (obtained from phytosterol). ...
Currently, industrial production is based on the chemical syntheses of corticosteroids from either 16- dehydropregnenolone acetate …
Discovery of highly potent proapoptotic antiestrogens in a series of androst-5,16-dienes D-modified with imidazole-annulated pendants.
Birukova V, Scherbakov A, Ilina A, Salnikova D, Andreeva O, Dzichenka Y, Zavarzin I, Volkova Y. Birukova V, et al. J Steroid Biochem Mol Biol. 2023 Jul;231:106309. doi: 10.1016/j.jsbmb.2023.106309. Epub 2023 Apr 8. J Steroid Biochem Mol Biol. 2023. PMID: 37037385
Novel C17-linked imidazole-annulated heterocyclic derivatives of dehydropregnenolone acetate were synthesized by the cyclocondensation with amidines using 3beta-acetoxy-21-bromopregna-5,16-dien-20-one as the substrate. ...
Novel C17-linked imidazole-annulated heterocyclic derivatives of dehydropregnenolone acetate were synthesized by the cyclocond …
Mixed culture bioconversion of 16-dehydropregnenolone acetate to androsta-1,4-diene-3,17-dione: optimization of parameters.
Banerjee T, Shukla A, Shinde K, Patil S. Banerjee T, et al. Biotechnol Prog. 2003 Mar-Apr;19(2):662-4. doi: 10.1021/bp025699m. Biotechnol Prog. 2003. PMID: 12675614
Bioconversion of 16-dehydropregnenolone acetate (16-DPA) to androsta-1,4-diene-3,17-dione (ADD), an intermediate for the production of female sex hormones, by mixed culture of Pseudomonas diminuta MTCC 3361 and Comamonas acidovorans MTCC 3362 is reported. ...
Bioconversion of 16-dehydropregnenolone acetate (16-DPA) to androsta-1,4-diene-3,17-dione (ADD), an intermediate for the produ …
26 results