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1982 1
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1993 1
1994 1
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Page 1
Concanamycin B inhibits the expression of newly-synthesized MHC class II molecules on the cell surface.
Ito K, Kobayashi T, Moriyama Y, Toshima K, Tatsuta K, Kakiuchi T, Futai M, Ploegh HL, Miwa K. Ito K, et al. J Antibiot (Tokyo). 1995 Jun;48(6):488-94. doi: 10.7164/antibiotics.48.488. J Antibiot (Tokyo). 1995. PMID: 7622435 Free article.
Concanamycin B also abrogates the enhancement of the MHC class II expression by IL-4 on mouse lymphocytes. Furthermore, concanamycin B suppresses the antigen presentation by MHC class II molecules....
Concanamycin B also abrogates the enhancement of the MHC class II expression by IL-4 on mouse lymphocytes. Furthermore, con …
Inhibition of the acidification of endosomes and lysosomes by the antibiotic concanamycin B in macrophage J774.
Woo JT, Shinohara C, Sakai K, Hasumi K, Endo A. Woo JT, et al. Eur J Biochem. 1992 Jul 1;207(1):383-9. doi: 10.1111/j.1432-1033.1992.tb17061.x. Eur J Biochem. 1992. PMID: 1628660 Free article.
Concanamycin B inhibited cholesteryl-ester synthesis from [14C]oleate by 50% at 14 nM without affecting the synthesis of triacylglycerol and polar lipids. ...When J774 cells were treated with 25 nM concanamycin B at 37 degrees C for 60 min, there was a …
Concanamycin B inhibited cholesteryl-ester synthesis from [14C]oleate by 50% at 14 nM without affecting the synthesis of triac …
Concanamycin A, a vacuolar type H(+)-ATPase inhibitor, induces cell death in activated CD8(+) CTL.
Togashi K, Kataoka T, Nagai K. Togashi K, et al. Cytotechnology. 1997 Nov;25(1-3):127-35. doi: 10.1023/A:1007995212658. Cytotechnology. 1997. PMID: 22358885 Free PMC article.
Concanamycin A (CMA) and concanamycin B (CMB) are specific inhibitors of vacuolar type H(+)-ATPase (V-ATPase). ...
Concanamycin A (CMA) and concanamycin B (CMB) are specific inhibitors of vacuolar type H(+)-ATPase (V-ATPase). ...
Is the vesicular nucleotide transporter a molecular target of eicosapentaenoic acid?
Moriyama Y, Hasuzawa N, Nomura M. Moriyama Y, et al. Front Pharmacol. 2022 Dec 7;13:1080189. doi: 10.3389/fphar.2022.1080189. eCollection 2022. Front Pharmacol. 2022. PMID: 36569286 Free PMC article.
However, our validation study indicated that, in bovine adrenal chromaffin granule membrane vesicles, EPA inhibited the formation of an electrochemical gradient of protons across the membrane with the concentration of 50% inhibition (IC50) being 1.0 muM without affecting conca …
However, our validation study indicated that, in bovine adrenal chromaffin granule membrane vesicles, EPA inhibited the formation of an elec …
In vivo rapid reduction of alloantigen-activated CD8+ mature cytotoxic T cells by inhibitors of acidification of intracellular organelles, prodigiosin 25-C and concanamycin B.
Lee MH, Kataoka T, Honjo N, Magae J, Nagai K. Lee MH, et al. Immunology. 2000 Feb;99(2):243-8. doi: 10.1046/j.1365-2567.2000.00961.x. Immunology. 2000. PMID: 10692043 Free PMC article.
Prodigiosin (PrG) 25-C and concanamycin B (CMB) are immunosuppressants that specifically inhibit the induction of cytotoxic T cells (CTL) without affecting the function of B cells and helper T cells in vivo. ...
Prodigiosin (PrG) 25-C and concanamycin B (CMB) are immunosuppressants that specifically inhibit the induction of cytotoxic T …
Prodigiosin 25-C suppression of cytotoxic T cells in vitro and in vivo similar to that of concanamycin B, a specific inhibitor of vacuolar type H(+)-ATPase.
Lee MH, Kataoka T, Magae J, Nagai K. Lee MH, et al. Biosci Biotechnol Biochem. 1995 Aug;59(8):1417-21. doi: 10.1271/bbb.59.1417. Biosci Biotechnol Biochem. 1995. PMID: 7549091 Free article.
The effects of prodigiosin 25-C (PrG) which preferentially suppresses cytotoxic T cells (CTL), was examined in comparison with concanamycin B (CMB), a specific inhibitor of vacuolar type H(+)-ATPase (V-ATPase). ...
The effects of prodigiosin 25-C (PrG) which preferentially suppresses cytotoxic T cells (CTL), was examined in comparison with concanamyc …
Concanamycin B, a vacuolar H(+)-ATPase specific inhibitor suppresses bone resorption in vitro.
Woo JT, Ohba Y, Tagami K, Sumitani K, Yamaguchi K, Tsuji T. Woo JT, et al. Biol Pharm Bull. 1996 Feb;19(2):297-9. doi: 10.1248/bpb.19.297. Biol Pharm Bull. 1996. PMID: 8850326
Effects of concanamycin B, a specific inhibitor of the vacuolar type H(+)-ATPase (V-ATPase), on the stimulation of bone resorption induced by parathyroid hormone (PTH) were examined in vitro. Concanamycin B was found to inhibit PTH-stimulated osteoclas …
Effects of concanamycin B, a specific inhibitor of the vacuolar type H(+)-ATPase (V-ATPase), on the stimulation of bone resorp …
How MHC class II molecules reach the endocytic pathway.
Bénaroch P, Yilla M, Raposo G, Ito K, Miwa K, Geuze HJ, Ploegh HL. Bénaroch P, et al. EMBO J. 1995 Jan 3;14(1):37-49. doi: 10.1002/j.1460-2075.1995.tb06973.x. EMBO J. 1995. PMID: 7530198 Free PMC article.
We have examined trafficking of major histocompatibility complex (MHC) class II molecules in human B cells exposed to concanamycin B, a highly specific inhibitor of the vacuolar H(+)-ATPases required for acidification of the vacuolar system and for early to late end …
We have examined trafficking of major histocompatibility complex (MHC) class II molecules in human B cells exposed to concanamycin …
Structures of concanamycins B and C.
Kinashi H, Sakaguchi K, Higashijima T, Miyazawa T. Kinashi H, et al. J Antibiot (Tokyo). 1982 Nov;35(11):1618-20. doi: 10.7164/antibiotics.35.1618. J Antibiot (Tokyo). 1982. PMID: 7161199 Free article. No abstract available.
24 results