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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 2
1991 8
1992 22
1993 21
1994 28
1995 27
1996 34
1997 27
1998 23
1999 22
2000 16
2001 14
2002 12
2003 9
2004 8
2005 13
2006 18
2007 17
2008 9
2009 15
2010 16
2011 10
2012 13
2013 16
2014 24
2015 14
2016 9
2017 14
2018 18
2019 15
2020 19
2021 5
2022 15
2023 13
2024 5

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503 results

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Page 1
Cocaine: An Updated Overview on Chemistry, Detection, Biokinetics, and Pharmacotoxicological Aspects including Abuse Pattern.
Roque Bravo R, Faria AC, Brito-da-Costa AM, Carmo H, Mladěnka P, Dias da Silva D, Remião F, On Behalf Of The Oemonom Researchers. Roque Bravo R, et al. Toxins (Basel). 2022 Apr 13;14(4):278. doi: 10.3390/toxins14040278. Toxins (Basel). 2022. PMID: 35448887 Free PMC article. Review.
Cocaine is metabolised (mostly hepatically) into two main metabolites, ecgonine methyl ester and benzoylecgonine. Other metabolites include, for example, norcocaine and cocaethylene, both displaying pharmacological action, and the last one constituting a biomarker for co-c …
Cocaine is metabolised (mostly hepatically) into two main metabolites, ecgonine methyl ester and benzoylecgonine. Other metabolites include, …
Forensic Drug Profile: Cocaethylene.
Jones AW. Jones AW. J Anal Toxicol. 2019 Apr 1;43(3):155-160. doi: 10.1093/jat/bkz007. J Anal Toxicol. 2019. PMID: 30796807 Review.
This article is intended as a brief review or primer about cocaethylene (CE), a pharmacologically active substance formed in the body when a person co-ingests ethanol and cocaine. ...
This article is intended as a brief review or primer about cocaethylene (CE), a pharmacologically active substance formed in the body …
Cocaethylene: When Cocaine and Alcohol Are Taken Together.
Pergolizzi J, Breve F, Magnusson P, LeQuang JAK, Varrassi G. Pergolizzi J, et al. Cureus. 2022 Feb 22;14(2):e22498. doi: 10.7759/cureus.22498. eCollection 2022 Feb. Cureus. 2022. PMID: 35345678 Free PMC article. Review.
Cocaethylene is the only known instance where a new psychoactive substance is formed entirely within the body. ...Cocaethylene has been studied in animal models in terms of its pharmacology and its potential neurological effects. ...
Cocaethylene is the only known instance where a new psychoactive substance is formed entirely within the body. ...Cocaethylene …
Cocaethylene toxicity.
Andrews P. Andrews P. J Addict Dis. 1997;16(3):75-84. doi: 10.1300/J069v16n03_08. J Addict Dis. 1997. PMID: 9243342 Review.
Concurrent use of cocaine and alcohol produces another psychoactive substance known as cocaethylene which has pharmacological properties similar to that of cocaine but which has a plasma half-life three to five times that of cocaine. This slow removal from the body makes i …
Concurrent use of cocaine and alcohol produces another psychoactive substance known as cocaethylene which has pharmacological propert …
The interaction of cocaethylene and cocaine and of cocaethylene and alcohol on schedule-controlled responding in rats.
Sobel BF, Riley AL. Sobel BF, et al. Psychopharmacology (Berl). 1999 Jul;145(2):153-61. doi: 10.1007/s002130051044. Psychopharmacology (Berl). 1999. PMID: 10463316
RATIONALE: Cocaethylene is a unique metabolite of cocaine, produced only in the presence of alcohol. ...CONCLUSIONS: The present study suggests behavioral interactions between cocaethylene and cocaine and between cocaethylene and alcohol. The contribution of …
RATIONALE: Cocaethylene is a unique metabolite of cocaine, produced only in the presence of alcohol. ...CONCLUSIONS: The present stud …
An overview of cocaethylene, an alcohol-derived, psychoactive, cocaine metabolite.
Landry MJ. Landry MJ. J Psychoactive Drugs. 1992 Jul-Sep;24(3):273-6. doi: 10.1080/02791072.1992.10471648. J Psychoactive Drugs. 1992. PMID: 1432406 Review.
Synthesized and administered cocaethylene has a behavioral stimulation profile similar to cocaine. ...With regard to lethality, cocaethylene has been shown to be more potent than cocaine in mice and rats. ...
Synthesized and administered cocaethylene has a behavioral stimulation profile similar to cocaine. ...With regard to lethality, co …
The importance of considering polysubstance use: lessons from cocaine research.
Liu Y, Guazzelli Williamson V, Setlow B, Cottler LB, Knackstedt LA. Liu Y, et al. Drug Alcohol Depend. 2018 Nov 1;192:16-28. doi: 10.1016/j.drugalcdep.2018.07.025. Epub 2018 Sep 1. Drug Alcohol Depend. 2018. PMID: 30195242 Free PMC article. Review.
Consumption of alcohol or cannabis with cocaine enhances subjective responses to cocaine, concomitant with changes in cocaine metabolism that increase blood cocaine levels, and, in the case of alcohol, produce the psychoactive metabolite cocaethylene. There is also consist …
Consumption of alcohol or cannabis with cocaine enhances subjective responses to cocaine, concomitant with changes in cocaine metabolism tha …
Cellular mechanisms of cocaine cardiotoxicity.
Welder AA, Grammas P, Melchert RB. Welder AA, et al. Toxicol Lett. 1993 Sep;69(3):227-38. doi: 10.1016/0378-4274(93)90028-v. Toxicol Lett. 1993. PMID: 8212064 Review.
Children victims of drug abuser parents: Hair testing as a forensic tool to assess exposure-A cohort of 37 cases from Spain.
García-Caballero C, Martínez-González MA. García-Caballero C, et al. Drug Test Anal. 2023 Sep;15(9):941-952. doi: 10.1002/dta.3478. Epub 2023 May 10. Drug Test Anal. 2023. PMID: 37041115
The 93.3% of these cases (n = 28) showed a positive result of cannabinoids (THC and CBN in hair and THC-COOH in urine; 71.4% n = 20), cocaine and metabolites (benzoylecgonine and cocaethylene; 46.4% n = 13), opiates (morphine and 6-acetylmorphine), and amphetamines (MDMA a …
The 93.3% of these cases (n = 28) showed a positive result of cannabinoids (THC and CBN in hair and THC-COOH in urine; 71.4% n = 20), cocain …
503 results