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1982 1
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Amaryllidaceae Alkaloids from Clivia miniata (Lindl.) Bosse (Amaryllidaceae): Isolation, Structural Elucidation, and Biological Activity.
Šafratová M, Křoustková J, Maafi N, Suchánková D, Vrabec R, Chlebek J, Kuneš J, Opletal L, Bucar F, Cahlíková L. Šafratová M, et al. Plants (Basel). 2022 Nov 10;11(22):3034. doi: 10.3390/plants11223034. Plants (Basel). 2022. PMID: 36432763 Free PMC article.
Eighteen known Amaryllidaceae alkaloids (AAs) of various structural types, and one undescribed alkaloid of homolycorine-type, named clivimine B (3), were isolated from Clivia miniata. The chemical structures of the isolated alkaloids were elucidated by a combination of MS, …
Eighteen known Amaryllidaceae alkaloids (AAs) of various structural types, and one undescribed alkaloid of homolycorine-type, named clivi …
Plant antiviral agents. III. Isolation of alkaloids from Clivia miniata Regel (Amaryllidaceae).
Ieven M, Vlietinck AJ, Vanden Berghe DA, Totte J, Dommisse R, Esmans E, Alderweireldt F. Ieven M, et al. J Nat Prod. 1982 Sep-Oct;45(5):564-73. doi: 10.1021/np50023a009. J Nat Prod. 1982. PMID: 7153775
Poliomyelitis virus inhibition occurred at lycorine concentrations as low as 1 microgram/ml, whereas concentrations exceeding 25 micrograms/ml were found to be cytotoxic. Clivimine (2), clivonine (3) and cliviamartine (4) were also isolated and characterized, but these alk …
Poliomyelitis virus inhibition occurred at lycorine concentrations as low as 1 microgram/ml, whereas concentrations exceeding 25 micrograms/ …
Biological evaluation of structurally diverse amaryllidaceae alkaloids and their synthetic derivatives: discovery of novel leads for anticancer drug design.
Evidente A, Kireev AS, Jenkins AR, Romero AE, Steelant WF, Van Slambrouck S, Kornienko A. Evidente A, et al. Planta Med. 2009 Apr;75(5):501-7. doi: 10.1055/s-0029-1185340. Epub 2009 Feb 23. Planta Med. 2009. PMID: 19235683 Free PMC article.
The collagen type I invasion assay revealed potent anti-invasive properties associated with N-methyllycorine iodide, hippeastrine, clivimine, buphanamine, and narciclasine tetraacetate, all of which were tested at non-toxic concentrations. ...
The collagen type I invasion assay revealed potent anti-invasive properties associated with N-methyllycorine iodide, hippeastrine, clivim …