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Page 1
Neuropathy target esterase inhibitors: enantiomeric separation and stereospecificity of 2-substituted-4H-1,3,2-benzodioxaphosphorin 2-oxides.
Wu SY, Casida JE. Wu SY, et al. Chem Res Toxicol. 1994 Jan-Feb;7(1):77-81. doi: 10.1021/tx00037a012. Chem Res Toxicol. 1994. PMID: 8155829
In addition to substituent effects, each of these compounds contains two enantiomers of unknown stereospecificity as NTE inhibitors. Separation by chiral HPLC with the CHIRALCEL OC column and hexane-2-propanol eluent gives individual enantiomers of > 98% e.e. and …
In addition to substituent effects, each of these compounds contains two enantiomers of unknown stereospecificity as NTE inhibitors. Separat …
Enantioselective separation of some polyunsaturated epoxy fatty acids by high-performance liquid chromatography on a cellulose phenylcarbamate (Chiralcel OC) stationary phase.
Oliw EH. Oliw EH. J Chromatogr. 1992 Dec 2;583(2):231-5. doi: 10.1016/0378-4347(92)80557-7. J Chromatogr. 1992. PMID: 1478987
cis-Epoxides of linoleic acid, alpha-linolenic acid, arachidonic acid and the omega 3-epoxide of eicosapentaenoic acid were chromatographed on a cellulose trisphenylcarbamate (Chiralcel OC) stationary phase in the normal-phase mode. ...
cis-Epoxides of linoleic acid, alpha-linolenic acid, arachidonic acid and the omega 3-epoxide of eicosapentaenoic acid were chromatographed …
Enantioselective assay of warfarin in blood plasma by liquid chromatography on Chiralcel OC.
Andersen C, Balmér K, Lagerstróm PO. Andersen C, et al. J Chromatogr. 1993 May 19;615(1):159-63. doi: 10.1016/0378-4347(93)80303-l. J Chromatogr. 1993. PMID: 8340455
After concentration by evaporation, the enantiomers are resolved by liquid chromatography on Chiralcel OC employing a non-polar mobile phase. By fluorometric detection, concentrations in plasma down to 80 nmol/l (25 ng/ml) can be determined with a coefficient of var …
After concentration by evaporation, the enantiomers are resolved by liquid chromatography on Chiralcel OC employing a non-pola …
Ambidextrous Chirality Transfer Capability from Cellulose Tris(phenylcarbamate) to Nonhelical Chainlike Luminophores: Achiral Solvent-Driven Helix-Helix Transition of Oligo- and Polyfluorenes Revealed by Sign Inversion of Circularly Polarized Luminescence and Circular Dichroism Spectra.
Guo S, Kamite H, Suzuki N, Wang L, Ohkubo A, Fujiki M. Guo S, et al. Biomacromolecules. 2018 Feb 12;19(2):449-459. doi: 10.1021/acs.biomac.7b01554. Epub 2018 Jan 8. Biomacromolecules. 2018. PMID: 29220164
Metabolism of halazepam by rat liver microsomes: stereoselective formation and N-dealkylation of 3-hydroxyhalazepam.
Lu XL, Yang SK. Lu XL, et al. Chirality. 1990;2(1):1-9. doi: 10.1002/chir.530020102. Chirality. 1990. PMID: 2400636
The relative amounts of major metabolites were found to be 3-hydroxy-HZ (3-OH-HZ) greater than N-desalkylhalazepam (NDZ, also known as N-desmethyldiazepam and nordiazepam) much greater than oxazepam (OX) for all three rat liver microsomal preparations and the distribution of meta …
The relative amounts of major metabolites were found to be 3-hydroxy-HZ (3-OH-HZ) greater than N-desalkylhalazepam (NDZ, also known as N-des …
Resolution of dihydroxyeicosanoates and of dihydroxyeicosatrienoates by chiral phase chromatography.
Capdevila JH, Wei S, Kumar A, Kobayashi J, Snapper JR, Zeldin DC, Bhatt RK, Falck JR. Capdevila JH, et al. Anal Biochem. 1992 Dec;207(2):236-40. doi: 10.1016/0003-2697(92)90006-s. Anal Biochem. 1992. PMID: 1481976
Following esterification, the individual methyl or pentafluorobenzyl esters are resolved by chiral-phase chromatography utilizing a Chiralcel OC or OD column. This methodology will find analytical and preparative applications since it is simple and efficient and pre …
Following esterification, the individual methyl or pentafluorobenzyl esters are resolved by chiral-phase chromatography utilizing a Chira
15 results