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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 2
1981 2
1982 3
1983 4
1984 4
1985 3
1986 3
1988 4
1989 1
1990 5
1991 1
1993 1
1994 2
1995 6
1996 3
1997 3
1998 5
1999 4
2000 6
2001 1
2003 2
2005 4
2006 1
2007 2
2008 2
2010 2
2012 1
2013 2
2014 1
2015 3
2016 1
2017 2
2020 1
2022 1
2024 0

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87 results

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Page 1
Coupling factors in nutrient-induced insulin release.
Malaisse WJ, Malaisse-Lagae F, Sener A. Malaisse WJ, et al. Experientia. 1984 Oct 15;40(10):1035-43. doi: 10.1007/BF01971449. Experientia. 1984. PMID: 6092124 Review. No abstract available.
Metabolic Regulation of Hormone Secretion in Beta-Cells and Alpha-Cells of Female Mice: Fundamental Differences.
Brüning D, Morsi M, Früh E, Scherneck S, Rustenbeck I. Brüning D, et al. Endocrinology. 2022 Oct 1;163(10):bqac125. doi: 10.1210/endocr/bqac125. Endocrinology. 2022. PMID: 35931024
Lowering glucose to 1 mM decreased the ratio to 69% within 10 minutes in beta-cells, but only to 94% in alpha-cells. In this situation, 30 mM glucose, 10 mM alpha-ketoisocaproic acid, and 10 mM glutamine plus 10 mM BCH (a nonmetabolizable leucine analogue) ma …
Lowering glucose to 1 mM decreased the ratio to 69% within 10 minutes in beta-cells, but only to 94% in alpha-cells. In this situation, 30 m …
Estrogen suppression in males: metabolic effects.
Mauras N, O'Brien KO, Klein KO, Hayes V. Mauras N, et al. J Clin Endocrinol Metab. 2000 Jul;85(7):2370-7. doi: 10.1210/jcem.85.7.6676. J Clin Endocrinol Metab. 2000. PMID: 10902781 Clinical Trial.
We have shown that testosterone (T) deficiency per se is associated with marked catabolic effects on protein, calcium metabolism, and body composition in men independent of changes in GH or insulin-like growth factor I production. ...Serum bone markers, osteocalcin and bon …
We have shown that testosterone (T) deficiency per se is associated with marked catabolic effects on protein, calcium metabolism, and …
AGI-1067, a novel antioxidant and anti-inflammatory agent, enhances insulin release and protects mouse islets.
Crim WS, Wu R, Carter JD, Cole BK, Trace AP, Mirmira RG, Kunsch C, Nadler JL, Nunemaker CS. Crim WS, et al. Mol Cell Endocrinol. 2010 Jul 29;323(2):246-55. doi: 10.1016/j.mce.2010.02.041. Epub 2010 Mar 6. Mol Cell Endocrinol. 2010. PMID: 20211684 Free PMC article.
AGI-1067-pretreated islets also showed enhanced calcium responses to methyl pyruvate and alpha-ketoisocaproate at low doses, but not high doses. The AGI-1067-mediated effects on glucose-stimulated calcium were maintained during continuous diazoxide exposure, suggest …
AGI-1067-pretreated islets also showed enhanced calcium responses to methyl pyruvate and alpha-ketoisocaproate at low doses, but not …
Fresh and cultured mouse islets differ in their response to nutrient stimulation.
Morsi M, Schulze T, Früh E, Brüning D, Panten U, Rustenbeck I. Morsi M, et al. Endocr Connect. 2020 Aug;9(8):769-782. doi: 10.1530/EC-20-0289. Endocr Connect. 2020. PMID: 32688335 Free PMC article.
This was also the response of cultured islets to the nutrient secretagogue alpha-ketoisocaproic acid, whereas the secretion of fresh islets increased similarly fast but remained strongly elevated. ...
This was also the response of cultured islets to the nutrient secretagogue alpha-ketoisocaproic acid, whereas the secre …
Nutrient secretagogues induce bimodal early changes in cytoplasmic calcium of insulin-releasing ob/ob mouse beta-cells.
Gylfe E. Gylfe E. J Biol Chem. 1988 Sep 25;263(27):13750-4. J Biol Chem. 1988. PMID: 3047130 Free article.
The cytoplasmic calcium concentration (Ca2+i) was measured in suspensions of fura-2 loaded mouse pancreatic beta-cells by continuously recording the 340/380 nm fluorescence excitation ratio. ...Qualitatively similar bimodal Ca2+i responses were obtained with 30 mM mannose, …
The cytoplasmic calcium concentration (Ca2+i) was measured in suspensions of fura-2 loaded mouse pancreatic beta-cells by continuousl …
Triphenyltin impairs insulin secretion by decreasing glucose-induced NADP(H) and ATP production in hamster pancreatic β-cells.
Miura Y, Hori Y, Kimura S, Hachiya H, Sakurai Y, Inoue K, Sawada T, Kubota K. Miura Y, et al. Toxicology. 2012 Sep 28;299(2-3):165-71. doi: 10.1016/j.tox.2012.05.021. Epub 2012 Jun 1. Toxicology. 2012. PMID: 22664483
However, TPT administration did not affect the increase of [Ca(2+)](i) and the insulin secretion by 30 mMK(+) or 100 muM tolbutamide, and the membrane potential by 30 mMK(+), and the insulin secretion by 10mM alpha-ketoisocaproic acid and 0.5mM formycin A, an …
However, TPT administration did not affect the increase of [Ca(2+)](i) and the insulin secretion by 30 mMK(+) or 100 muM tolbutamide, and th …
Functional differences between aggregated and dispersed insulin-producing cells.
Chowdhury A, Dyachok O, Tengholm A, Sandler S, Bergsten P. Chowdhury A, et al. Diabetologia. 2013 Jul;56(7):1557-68. doi: 10.1007/s00125-013-2903-3. Epub 2013 Apr 19. Diabetologia. 2013. PMID: 23604550 Free PMC article.
METHODS: MIN6 monolayers, pseudoislets and mouse and human islets were exposed to glucose, alpha-ketoisocaproic acid (KIC), pyruvate, KIC plus glutamine and the phosphatidylinositol 3-kinase (PI3K) inhibitors LY294002 or wortmannin. ...
METHODS: MIN6 monolayers, pseudoislets and mouse and human islets were exposed to glucose, alpha-ketoisocaproic acid (K …
87 results