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1989 | 1 |
1990 | 1 |
2024 | 0 |
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Acid-sensitive latent inhibitors for proteolytic enzymes: synthesis and characterization.
J Med Chem. 1989 Jun;32(6):1253-9. doi: 10.1021/jm00126a018.
J Med Chem. 1989.
PMID: 2724298
When BzPheal = Ala is introduced into ongoing reactions catalyzed by alpha-chymotrypsin or papain, the rate of these reactions diminishes more rapidly with time than do those of controls lacking BzPheal = Ala. ...The data are quantitatively explained b …
When BzPheal = Ala is introduced into ongoing reactions catalyzed by alpha-chymotrypsin or papain, the rate of these reactions …
Chemistry in a microenvironment of low pH, generated with the aid of an immobilized proteinase.
Silver MS, Haskell JH.
Silver MS, et al.
Biochim Biophys Acta. 1990 May 31;1039(1):25-32. doi: 10.1016/0167-4838(90)90222-2.
Biochim Biophys Acta. 1990.
PMID: 2354198
The presence of this locally highly acidic region produces a marked increase in the rate of hydrolysis of BzPheal = Ala dissolved in the buffer solution (BzPheal = Ala is the acylhydrazide obtained from the reaction between N-benzoyl-L-phenylalaninal a …
The presence of this locally highly acidic region produces a marked increase in the rate of hydrolysis of BzPheal = Ala dissol …
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