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Use of rat and human in vitro systems to assess the effectiveness and enzymology of deoxyguanine analogs as prodrugs of an antiviral agent.
Harrell AW, Wheeler SM, East P, Clarke SE, Chenery RJ. Harrell AW, et al. Drug Metab Dispos. 1994 Mar-Apr;22(2):189-93. Drug Metab Dispos. 1994. PMID: 8013273
BRL 55792, BRL 55791, and BRL 55039 are prodrugs of an active antiviral agent 9-(3-hydroxypropoxy) guanine (BRL 44385). The prodrugs were 6-deoxygenated analogs of BRL 44385, with ether groups substituted at the 9-position: …
BRL 55792, BRL 55791, and BRL 55039 are prodrugs of an active antiviral agent 9-(3-hydroxypropoxy) guanine (B …
Use of rat and human in vitro systems to assess the effectiveness and enzymology of deoxy-guanine analogues as prodrugs of an antiviral agent.
Harrell AW, Wheeler SM, East P, Clarke SE, Chenery RJ. Harrell AW, et al. Drug Metab Dispos. 1994 Jan-Feb;22(1):124-8. Drug Metab Dispos. 1994. PMID: 8149871
BRL 55792, BRL 55791, and BRL 55039 are prodrugs of an active anti-viral agent 9-(3-hydroxypropoxy) guanine, (BRL 44385). The prodrugs were 6-deoxygenated analogues of BRL 44385 with ether groups substituted at the 9-positio …
BRL 55792, BRL 55791, and BRL 55039 are prodrugs of an active anti-viral agent 9-(3-hydroxypropoxy) guanine, ( …