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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 39
1993 106
1994 134
1995 184
1996 141
1997 120
1998 136
1999 83
2000 105
2001 87
2002 84
2003 58
2004 85
2005 71
2006 67
2007 51
2008 58
2009 48
2010 51
2011 38
2012 47
2013 35
2014 33
2015 25
2016 23
2017 23
2018 28
2019 13
2020 9
2021 10
2022 12
2023 5
2024 0

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1,913 results

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Page 1
Effect of avosentan (SPP-301) in porcine ciliary arteries.
Konieczka K, Meyer P, Schoetzau A, Neutzner A, Mozaffarieh M, Flammer J. Konieczka K, et al. Curr Eye Res. 2011 Feb;36(2):118-24. doi: 10.3109/02713683.2010.529982. Curr Eye Res. 2011. PMID: 21281066
PURPOSE: To investigate the vasoactive effect of ET(A)-endothelin receptor antagonists avosentan (SPP-301) and BQ-123 in isolated porcine ciliary arteries with and without endothelium. ...In a first set of experiments, quiescent vessels were exposed, cumulatively, t …
PURPOSE: To investigate the vasoactive effect of ET(A)-endothelin receptor antagonists avosentan (SPP-301) and BQ-123 in isola …
Effect and Mechanism of Endothelin Receptor A Inhibitor BQ-123 Combined with Electroacupuncture on Tibia Cancer Pain in Rats.
Tang J, Sun Z, Wang Y, Liu J, Wang S, Wang X. Tang J, et al. Dis Markers. 2022 May 17;2022:8563202. doi: 10.1155/2022/8563202. eCollection 2022. Dis Markers. 2022. PMID: 35620269 Free PMC article.
The histology of the right tibia was observed by hematoxylin-eosin (HE) staining. The remaining rats were randomly divided into model, BQ-123, electroacupuncture, and BQ-123+ electroacupuncture group. ...The mRNA expression of alpha-SMA and ETAR in …
The histology of the right tibia was observed by hematoxylin-eosin (HE) staining. The remaining rats were randomly divided into model, BQ …
Effects of endothelin-1 and the ETA receptor antagonist BQ-123 on resistance arteries from normal pregnant and preeclamptic women.
Wolff K, Kublickiene KR, Kublickas M, Lindblom B, Lunell NO, Nisell H. Wolff K, et al. Acta Obstet Gynecol Scand. 1996 May;75(5):432-8. doi: 10.3109/00016349609033349. Acta Obstet Gynecol Scand. 1996. PMID: 8677766 Review.
The contractile response to endothelin-1 in presence and absence of BQ-123 was recorded. RESULTS: Endothelin-1 induced similar concentration-dependent contractions in all arteries investigated. In women with preeclampsia the contractile response induced by endotheli …
The contractile response to endothelin-1 in presence and absence of BQ-123 was recorded. RESULTS: Endothelin-1 induced similar …
Synergistic inhibition by BQ-123 and BQ-788 of endothelin-1-induced contractions of the rabbit pulmonary artery.
Fukuroda T, Ozaki S, Ihara M, Ishikawa K, Yano M, Nishikibe M. Fukuroda T, et al. Br J Pharmacol. 1994 Oct;113(2):336-8. doi: 10.1111/j.1476-5381.1994.tb16901.x. Br J Pharmacol. 1994. PMID: 7834180 Free PMC article.
However, the combination of BQ-123 and BQ-788 completely inhibited the ET-1-induced contraction. In contrast, the ETB-selective agonist, sarafotoxin S6c (1 nM)-induced contraction was completely inhibited by BQ-788 but not by BQ-123. In receptor bindin …
However, the combination of BQ-123 and BQ-788 completely inhibited the ET-1-induced contraction. In contrast, the ETB-selectiv …
Role of Endothelin-1 Receptors in Limiting Leg Blood Flow and Glucose Uptake During Hyperinsulinemia in Type 2 Diabetes.
Young BE, Padilla J, Finsen SH, Fadel PJ, Mortensen SP. Young BE, et al. Endocrinology. 2022 Mar 1;163(3):bqac008. doi: 10.1210/endocr/bqac008. Endocrinology. 2022. PMID: 35084435 Free PMC article.
The LBF responses to hyperinsulinemia alone tended to be lower in T2D (controls: 161 160 mL/minute; T2D: 58 43 mL/minute, P = .08). BQ-123 during hyperinsulinemia augmented LBF to a greater extent in T2D (% change: controls: 14 23%; T2D: 38 21%, P = .029). LGU follo …
The LBF responses to hyperinsulinemia alone tended to be lower in T2D (controls: 161 160 mL/minute; T2D: 58 43 mL/minute, P = .08). BQ …
Characterization of ETB receptors mediating contractions induced by endothelin-1 or IRL 1620 in guinea-pig isolated airways: effects of BQ-123, FR139317 or PD 145065.
Battistini B, Warner TD, Fournier A, Vane JR. Battistini B, et al. Br J Pharmacol. 1994 Apr;111(4):1009-16. doi: 10.1111/j.1476-5381.1994.tb14844.x. Br J Pharmacol. 1994. PMID: 8032583 Free PMC article.
In the trachea, contraction to ET-1 (< 10(-8) M) was preceded by a transient relaxation which was inhibited by BQ-123 (10(-5) M) or FR 139317 (10(-5) M) or by the removal of the epithelium. ...The contractile action of ET-1 in the lung parenchyma was significantl …
In the trachea, contraction to ET-1 (< 10(-8) M) was preceded by a transient relaxation which was inhibited by BQ-123 (10(- …
Endothelinergic Contractile Hyperreactivity in Rat Contralateral Carotid to Balloon Injury: Integrated Role for ETB Receptors and Superoxide Anion.
Pernomian L, Gimenes LR, Gomes MS, do Vale BN, Cardoso CRB, de Oliveira AM, Moreira JD. Pernomian L, et al. Biomed Res Int. 2017;2017:3137580. doi: 10.1155/2017/3137580. Epub 2017 Sep 14. Biomed Res Int. 2017. PMID: 29062837 Free PMC article.
Endothelin-1-induced calcium mobilization was evaluated in functional assays carried out with BQ-123, BQ-788, or Tempol. Endothelin-1-induced NADPH oxidase-driven superoxide generation was measured by lucigenin chemiluminescence assays performed with BQ-12 …
Endothelin-1-induced calcium mobilization was evaluated in functional assays carried out with BQ-123, BQ-788, or Tempol. Endot …
Effects of phosphoramidon, BQ 788, and BQ 123 on coronary and cardiac dysfunctions of the failing hamster heart.
Fontaine ER, Viau S, Jasmin G, Dumont L. Fontaine ER, et al. J Cardiovasc Pharmacol. 1998 Jul;32(1):12-20. doi: 10.1097/00005344-199807000-00003. J Cardiovasc Pharmacol. 1998. PMID: 9676715
Coronary and cardiac effects of exogenous ET-1 (0.01-100 pmol) were also studied. Phosphoramidon, BQ 788, and BQ 123 did not altered coronary perfusion pressure either in normal or in failing hearts, whereas cardiac contractility was significantly impaired in the pr …
Coronary and cardiac effects of exogenous ET-1 (0.01-100 pmol) were also studied. Phosphoramidon, BQ 788, and BQ 123 did not a …
Co-targeting of endothelin-A and vitamin D receptors: a novel strategy to ameliorate cisplatin-induced nephrotoxicity.
Abdel Moneim LM, Helmy MW, El-Abhar HS. Abdel Moneim LM, et al. Pharmacol Rep. 2019 Oct;71(5):917-925. doi: 10.1016/j.pharep.2019.04.018. Epub 2019 Apr 25. Pharmacol Rep. 2019. PMID: 31430707
METHODS: Male Sprague-Dawley rats were divided into the following groups: control (DMSO orally), cisplatin (single dose of 6 mg/kg ip; nephrotoxicity model), cisplatin + BQ-123 (1 mg/kg BQ-123 ip 1 h before and 1 day after cisplatin), cisplatin + alfac …
METHODS: Male Sprague-Dawley rats were divided into the following groups: control (DMSO orally), cisplatin (single dose of 6 mg/kg ip; nephr …
The role of ET(A) and ET(B) receptor antagonists in acute and allergic inflammation in mice.
Kassuya CA, Rogerio AP, Calixto JB. Kassuya CA, et al. Peptides. 2008 Aug;29(8):1329-37. doi: 10.1016/j.peptides.2008.03.008. Epub 2008 Mar 16. Peptides. 2008. PMID: 18632188
The intraplantar injection of BQ-123, but not BQ-788, significantly inhibited carrageenan-, PAF-, ET-1- and bradykinin-induced paw edema formation. ...BQ-123 also inhibited the indirect macrophage influx induced by carrageenan (55+/-6%). ...
The intraplantar injection of BQ-123, but not BQ-788, significantly inhibited carrageenan-, PAF-, ET-1- and bradykinin-induced …
1,913 results