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Year Number of Results
1980 2
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1988 2
1989 1
1990 1
1992 1
1994 1
1995 1
1997 2
1998 2
2001 2
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2009 5
2010 1
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2024 0

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65 results

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Page 1
Desipramine prevents cardiac gap junction uncoupling.
Jozwiak J, Dietze A, Grover R, Savtschenko A, Etz C, Mohr FW, Dhein S. Jozwiak J, et al. Naunyn Schmiedebergs Arch Pharmacol. 2012 Nov;385(11):1063-75. doi: 10.1007/s00210-012-0795-2. Epub 2012 Sep 11. Naunyn Schmiedebergs Arch Pharmacol. 2012. PMID: 22965471
BACKGROUND AND PURPOSE: Uncoupling of cardiac gap junction channels is an important arrhythmogenic mechanism in ischemia/reperfusion. Antiarrhythmic peptide AAP10 (H-Gly-Ala-Gly-Hyp-Pro-Tyr-CONH(2)) has been shown to prevent acidosis-induced uncoupling and ischemia- …
BACKGROUND AND PURPOSE: Uncoupling of cardiac gap junction channels is an important arrhythmogenic mechanism in ischemia/reperfusion. Ant …
Effects of antiarrhythmic peptide 10 on acute ventricular arrhythmia.
Sun B, Jiang JF, Zhao CM, Hu CH. Sun B, et al. Asian Pac J Trop Med. 2015 Mar;8(3):229-33. doi: 10.1016/S1995-7645(14)60321-7. Asian Pac J Trop Med. 2015. PMID: 25902167 Free article.
OBJECTIVE: To observe the effects antiarrhythmic peptide 10 (AAP10) aon acute ventricular arrhythmia and the phosphorylation state of ischemic myocardium connexin. ...
OBJECTIVE: To observe the effects antiarrhythmic peptide 10 (AAP10) aon acute ventricular arrhythmia and the phosphorylation s …
Increasing gap junctional coupling: a tool for dissecting the role of gap junctions.
Axelsen LN, Haugan K, Stahlhut M, Kjølbye AL, Hennan JK, Holstein-Rathlou NH, Petersen JS, Nielsen MS. Axelsen LN, et al. J Membr Biol. 2007 Mar;216(1):23-35. doi: 10.1007/s00232-007-9026-z. Epub 2007 Jun 14. J Membr Biol. 2007. PMID: 17568971 Review.
Two approaches will be reviewed: increasing coupling by the use of antiarrhythmic peptide and its synthetic analogs and by interfering with the gating of gap junctional channels....
Two approaches will be reviewed: increasing coupling by the use of antiarrhythmic peptide and its synthetic analogs and by int …
Effects of the new antiarrhythmic peptide ZP123 on epicardial activation and repolarization pattern.
Dhein S, Larsen BD, Petersen JS, Mohr FW. Dhein S, et al. Cell Commun Adhes. 2003 Jul-Dec;10(4-6):371-8. doi: 10.1080/cac.10.4-6.371.378. Cell Commun Adhes. 2003. PMID: 14681044
However, most of these peptides are not stable in enzymatic environment which limits studies with these compounds in vivo. ZP123 is a new antiarrhythmic peptide constructed using a retro-all-D-amino acid design of the AAP10 template (Ac-D-Tyr-D-Pro-D-4Hyp-Gly-D-Ala- …
However, most of these peptides are not stable in enzymatic environment which limits studies with these compounds in vivo. ZP123 is a new …
The antiarrhythmic peptide analog ZP123 prevents atrial conduction slowing during metabolic stress.
Haugan K, Olsen KB, Hartvig L, Petersen JS, Holstein-Rathlou NH, Hennan JK, Nielsen MS. Haugan K, et al. J Cardiovasc Electrophysiol. 2005 May;16(5):537-45. doi: 10.1111/j.1540-8167.2005.40687.x. J Cardiovasc Electrophysiol. 2005. PMID: 15877626
In this study, we investigated whether the novel stable antiarrhythmic peptide analog, ZP123, was able to prevent atrial conduction slowing. ...
In this study, we investigated whether the novel stable antiarrhythmic peptide analog, ZP123, was able to prevent atrial condu …
Human cardiac gap-junction coupling: effects of antiarrhythmic peptide AAP10.
Hagen A, Dietze A, Dhein S. Hagen A, et al. Cardiovasc Res. 2009 Jul 15;83(2):405-15. doi: 10.1093/cvr/cvp028. Epub 2009 Jan 28. Cardiovasc Res. 2009. PMID: 19176598
We wanted to examine whether the gap junction modulator (antiarrhythmic peptide) AAP10 exerts effects on human cardiac gap junctions, whether the effect might be enhanced in uncoupled cells, whether it affects electrical and metabolic coupling, and which of the card …
We wanted to examine whether the gap junction modulator (antiarrhythmic peptide) AAP10 exerts effects on human cardiac gap jun …
Increasing gap junction coupling suppresses ibutilide-induced torsades de pointes.
Ruan L, Quan X, Li L, Bai R, Ni M, Xu R, Zhang C. Ruan L, et al. Exp Ther Med. 2014 May;7(5):1279-1284. doi: 10.3892/etm.2014.1601. Epub 2014 Mar 4. Exp Ther Med. 2014. PMID: 24940425 Free PMC article.
The present study examined the effect of a gap junction enhancer, antiarrhythmic peptide 10 (AAP10), on ibutilide-induced TdP. Coronary-perfused rabbit ventricular wedge preparations were used to evaluate the effect of AAP10 on ibutilide-induced arrhythmia. ...
The present study examined the effect of a gap junction enhancer, antiarrhythmic peptide 10 (AAP10), on ibutilide-induced TdP. …
65 results