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Electrophysiologic effects of alprafenone on canine cardiac tissue.
Anyukhovsky EP, Rosen MR. Anyukhovsky EP, et al. J Cardiovasc Pharmacol. 1994 Sep;24(3):411-9. doi: 10.1097/00005344-199409000-00009. J Cardiovasc Pharmacol. 1994. PMID: 7528297
We studied the actions of the propafenone derivative alprafenone on transmembrane action potentials (APs) of canine Purkinje fibers (PF) and ventricular and atrial muscle. ...Alprafenone inhibited both early and delayed afterdepolarizations and eliminated triggered …
We studied the actions of the propafenone derivative alprafenone on transmembrane action potentials (APs) of canine Purkinje fibers ( …
Negative inotropic effects of the new class I antiarrhythmic agents berlafenone and alprafenone on electrically stimulated isolated cardiomyocytes.
Rose H, Ionescu I, Pöpping S, Fischer Y, Kammermeier H. Rose H, et al. Arzneimittelforschung. 1992 Mar;42(3):289-91. Arzneimittelforschung. 1992. PMID: 1497686
Isolated cardiac myocytes from adult rats were used in a stimulation chamber to investigate the negative inotropic effects of propafenone and the new compounds berlafenone (1-2'-biphenyloxy)-3-tert-butylamino-propanol-2-hydrochloride, GK 23 G; CAS 18965-97-4) and alprafenone …
Isolated cardiac myocytes from adult rats were used in a stimulation chamber to investigate the negative inotropic effects of propafenone an …