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1998 1
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Page 1
Triazole antifungals: a review.
Peyton LR, Gallagher S, Hashemzadeh M. Peyton LR, et al. Drugs Today (Barc). 2015 Dec;51(12):705-18. doi: 10.1358/dot.2015.51.12.2421058. Drugs Today (Barc). 2015. PMID: 26798851 Review.
Second-generation triazoles such as voriconazole, posa-conazole, albaconazole, efinaconazole, ravuconazole and isavuconazole are all derivatives of either itraconazole or fluconazole, and designed to overcome the deficiencies of their parent drugs. ...
Second-generation triazoles such as voriconazole, posa-conazole, albaconazole, efinaconazole, ravuconazole and isavuconazole are all …
Newer antifungal agents.
Türel O. Türel O. Expert Rev Anti Infect Ther. 2011 Mar;9(3):325-38. doi: 10.1586/eri.10.163. Expert Rev Anti Infect Ther. 2011. PMID: 21417872 Review.
The aim of this article is to summarize the studies involving isavuconazole, ravuconazole, albaconazole, aminocandin and some other investigational antifungal agents. Most data on the clinical use of ravuconazole, isavuconazole and albaconazole are mainly available …
The aim of this article is to summarize the studies involving isavuconazole, ravuconazole, albaconazole, aminocandin and some other i …
In vitro susceptibilities of Malassezia species to a new triazole, albaconazole (UR-9825), and other antifungal compounds.
Garau M, Pereiro M Jr, del Palacio A. Garau M, et al. Antimicrob Agents Chemother. 2003 Jul;47(7):2342-4. doi: 10.1128/AAC.47.7.2342-2344.2003. Antimicrob Agents Chemother. 2003. PMID: 12821494 Free PMC article.
The in vitro activity of the new triazole albaconazole (UR-9825) in comparison with those of flucytosine, fluconazole, ketoconazole, itraconazole, and voriconazole against 70 strains of Malassezia spp. was determined by a microdilution method using a colorime …
The in vitro activity of the new triazole albaconazole (UR-9825) in comparison with those of flucytosine, fluconazole, …
Emerging azole antifungals.
Chen A, Sobel JD. Chen A, et al. Expert Opin Emerg Drugs. 2005 Feb;10(1):21-33. doi: 10.1517/14728214.10.1.21. Expert Opin Emerg Drugs. 2005. PMID: 15757401 Review.
A new generation of triazoles that includes voriconazole, posaconazole, ravuconazole and albaconazole has emerged and are presently in different phases of clinical investigation. ...
A new generation of triazoles that includes voriconazole, posaconazole, ravuconazole and albaconazole has emerged and are presently i …
In-vitro comparative activity of UR-9825, itraconazole and fluconazole against clinical isolates of Candida spp.
Ramos G, Cuenca-Estrella M, Monzón A, Rodríguez-Tudela JL. Ramos G, et al. J Antimicrob Chemother. 1999 Aug;44(2):283-6. doi: 10.1093/jac/44.2.283. J Antimicrob Chemother. 1999. PMID: 10473237
UR-9825 is a new broad-spectrum triazole antifungal agent with a good pharmacokinetic profile and excellent bioavailability. ...The purpose of this study was to evaluate the in-vitro activity of UR-9825 and to compare it with that of fluconazole and it
UR-9825 is a new broad-spectrum triazole antifungal agent with a good pharmacokinetic profile and excellent bioavailability. .
Efficacy of albaconazole (UR-9825) in treatment of disseminated Scedosporium prolificans infection in rabbits.
Capilla J, Yustes C, Mayayo E, Fernández B, Ortoneda M, Pastor FJ, Guarro J. Capilla J, et al. Antimicrob Agents Chemother. 2003 Jun;47(6):1948-51. doi: 10.1128/AAC.47.6.1948-1951.2003. Antimicrob Agents Chemother. 2003. PMID: 12760872 Free PMC article.
Doses of 15, 25, and 50 mg/kg of body weight/day for the new triazole albaconazole (ABC) were evaluated in an immunocompetent rabbit model of systemic infection with this mold. ...
Doses of 15, 25, and 50 mg/kg of body weight/day for the new triazole albaconazole (ABC) were evaluated in an immunocompetent rabbit …
In vitro antifungal activities of the new triazole UR-9825 against clinically important filamentous fungi.
Capilla J, Ortoneda M, Pastor FJ, Guarro J. Capilla J, et al. Antimicrob Agents Chemother. 2001 Sep;45(9):2635-7. doi: 10.1128/AAC.45.9.2635-2637.2001. Antimicrob Agents Chemother. 2001. PMID: 11502542 Free PMC article.
UR-9825 was clearly more active than amphotericin B against all fungi except Fusarium solani and Scytalidium spp. Notably, UR-9825 had low MICs for Aspergillus fumigatus and Paecilomyces lilacinus (MICs at which 90% of isolates are inhibited, 0.125 mic
UR-9825 was clearly more active than amphotericin B against all fungi except Fusarium solani and Scytalidium spp. Notably,
Emerging drugs and vaccines for candidemia.
Moriyama B, Gordon LA, McCarthy M, Henning SA, Walsh TJ, Penzak SR. Moriyama B, et al. Mycoses. 2014 Dec;57(12):718-33. doi: 10.1111/myc.12265. Epub 2014 Oct 8. Mycoses. 2014. PMID: 25294098 Free PMC article. Review.
Antifungal agents currently in clinical trials include isavuconazole, albaconazole, SCY-078, VT-1161 and T-2307. Further data are needed to determine the role of these compounds in the treatment of candidemia and other forms of invasive candidiasis. ...
Antifungal agents currently in clinical trials include isavuconazole, albaconazole, SCY-078, VT-1161 and T-2307. Further data are nee …
Novel triazole antifungal drugs: focus on isavuconazole, ravuconazole and albaconazole.
Pasqualotto AC, Thiele KO, Goldani LZ. Pasqualotto AC, et al. Curr Opin Investig Drugs. 2010 Feb;11(2):165-74. Curr Opin Investig Drugs. 2010. PMID: 20112166 Review.
This review focuses on three azoles: isavuconazole, ravuconazole and albaconazole (Stiefel). These drugs exhibit a broad spectrum of activity in vitro, including activity against several fungal isolates that are resistant to other azoles. ...As isavuconazole and ravuconazo …
This review focuses on three azoles: isavuconazole, ravuconazole and albaconazole (Stiefel). These drugs exhibit a broad spectrum of …
Oral antifungal therapies for toenail onychomycosis: a systematic review with network meta-analysis toenail mycosis: network meta-analysis.
Fávero MLD, Bonetti AF, Domingos EL, Tonin FS, Pontarolo R. Fávero MLD, et al. J Dermatolog Treat. 2022 Feb;33(1):121-130. doi: 10.1080/09546634.2020.1729336. Epub 2020 Feb 20. J Dermatolog Treat. 2022. PMID: 32043906
Ranking probabilities were calculated by surface under the cumulative ranking analysis (SUCRA). RESULTS: We included 40 trials (n = 9568). Albaconazole 400 mg (OR 0.02 [95% CrI 0.01-0.07] versus placebo), followed by posaconazole 200-400 mg and terbinafine 250-350 mg were …
Ranking probabilities were calculated by surface under the cumulative ranking analysis (SUCRA). RESULTS: We included 40 trials (n = 9568). …
53 results