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Inhibitory effects of antiviral compounds on respiratory syncytial virus replication in vitro.
Kawana F, Shigeta S, Hosoya M, Suzuki H, De Clercq E. Kawana F, et al. Antimicrob Agents Chemother. 1987 Aug;31(8):1225-30. doi: 10.1128/AAC.31.8.1225. Antimicrob Agents Chemother. 1987. PMID: 3307618 Free PMC article.
., 3-adenin-9-yl-2-hydroxypropanoic acid isobutyl ester, 3-deazauridine, 3'-C-methyluridine, 5'-deoxy-5-fluorouridine, 5-cyanoimidazole-4-carboxamide, and its ribofuranosyl derivative, did not inhibit the cytopathic effect of the Long strain of respiratory syncytial virus at conc …
., 3-adenin-9-yl-2-hydroxypropanoic acid isobutyl ester, 3-deazauridine, 3'-C-methyluridine, 5'-deoxy-5-fluorouridine, 5-cyanoimidazole-4-ca …
Halogenation of tubercidin by N-halosuccinimides. A direct route to 5-bromotubercidin, a reversible inhibitor of RNA synthesis in eukaryotic cells.
Bergstrom DE, Brattesani AJ. Bergstrom DE, et al. Nucleic Acids Res. 1980 Dec 20;8(24):6213-9. doi: 10.1093/nar/8.24.6213. Nucleic Acids Res. 1980. PMID: 6162160 Free PMC article.
When buffered with potassium acetate the major product is 6-bromotubercidin. 5,6-Dibromotubercidin is formed in minor amounts under both conditions. N-Chlorosuccinimide and tubercidin give 5-chlorotubercidin and 5,6-dichlorotubercidin....
When buffered with potassium acetate the major product is 6-bromotubercidin. 5,6-Dibromotubercidin is formed in minor amounts under both con …