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Global Metabolomics Reveals the Metabolic Dysfunction in Ox-LDL Induced Macrophage-Derived Foam Cells.
Xu W, Wei Z, Dong J, Duan F, Chen K, Chen C, Liu J, Yang X, Chen L, Xiao H, Liu A. Xu W, et al. Front Pharmacol. 2017 Aug 31;8:586. doi: 10.3389/fphar.2017.00586. eCollection 2017. Front Pharmacol. 2017. PMID: 28912717 Free PMC article.
Multivariate statistical analyses identified five metabolites (25-azacholesterol, anandamide, glycocholate, oleoyl ethanolamide, and 3-oxo-4, 6-choladienoate) for distinguishing foamy macrophages from controls. ...
Multivariate statistical analyses identified five metabolites (25-azacholesterol, anandamide, glycocholate, oleoyl ethanolamid …
Azasterol inhibition of delta 24-sterol methyltransferase in Saccharomyces cerevisiae.
Oehlschlager AC, Angus RH, Pierce AM, Pierce HD Jr, Srinivasan R. Oehlschlager AC, et al. Biochemistry. 1984 Jul 31;23(16):3582-9. doi: 10.1021/bi00311a003. Biochemistry. 1984. PMID: 6383468
Inhibitory power [I50 (microM)] was found to be in the order of 25-azacholesterol hydrochloride salt (0.05) greater than 25-aza-24,25-dihydrozymosterol (0.08) greater than 25-azacholesterol approximately equal to 25-azacholestanol (0.14) greater than ( …
Inhibitory power [I50 (microM)] was found to be in the order of 25-azacholesterol hydrochloride salt (0.05) greater than 25-az …
Neuromuscular failure in myotonic rats.
Mrozek K, Kwieciński H. Mrozek K, et al. Eur Neurol. 1975;13(1):47-53. doi: 10.1159/000114661. Eur Neurol. 1975. PMID: 1126346
Myotonia-like activity was recorded from various muscles of rats treated with 25-azacholesterol for a period of 2-8 weeks. 50% of myotonic rats showed a decline of amplitude of the evoked muscle potentials of the flexor digitorum muscle on stimulation of the median …
Myotonia-like activity was recorded from various muscles of rats treated with 25-azacholesterol for a period of 2-8 weeks. 50% …
Purification, characterization and catalytic properties of human sterol 8-isomerase.
Nes WD, Zhou W, Dennis AL, Li H, Jia Z, Keith RA, Piser TM, Furlong ST. Nes WD, et al. Biochem J. 2002 Nov 1;367(Pt 3):587-99. doi: 10.1042/BJ20020551. Biochem J. 2002. PMID: 12133002 Free PMC article.
Treatment of hSI with different high-energy intermediate analogues produced the following dissociation constants ( K (i)): emopamil (2 microM)=tamoxifen (1 microM)=tridemorph (1 microM)<25-azacholesterol (21 microM) <ketoconazole (156 microM)<cholesterol (6 …
Treatment of hSI with different high-energy intermediate analogues produced the following dissociation constants ( K (i)): emopamil (2 micro …