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Characterization of 2,3-bis(chloromethyl)-1,4-naphthoquinone induced mitochondrial swelling.
Pardini RS, Tilka MA, Pritsos CA, Lin AJ, Sartorelli AC. Pardini RS, et al. Chem Biol Interact. 1981 May;35(2):241-53. doi: 10.1016/0009-2797(81)90147-2. Chem Biol Interact. 1981. PMID: 7214604
Mitochondrial swelling induced by 2,3-bis(chloromethyl)-1,4-naphthoquinone (CMNQ) was found to be a non-energy linked, oxygen and sulfhydryl-dependent, substrate-independent, osmotic process, that lack cation specificity. ...
Mitochondrial swelling induced by 2,3-bis(chloromethyl)-1,4-naphthoquinone (CMNQ) was found …
The inhibition by a series of potentially bioreductive naphthoquinones of rat liver mitochondria and sarcoma 180 tumor cell respiration.
Biagini RE, Tilka MA, Pardini RS. Biagini RE, et al. Res Commun Chem Pathol Pharmacol. 1981 Aug;33(2):293-304. Res Commun Chem Pathol Pharmacol. 1981. PMID: 7302377
It was also found that 1,4-naphthoquinones substituted at the 2 and 3 positions were more effective inhibitors of the respiratory and energy transfer systems studied than those substituted at the 2 position only. 2,3-bis(chloromethyl) 1,4 …
It was also found that 1,4-naphthoquinones substituted at the 2 and 3 positions were more effective inhibitors of the respiratory and energy …