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The following term was not found in PubMed: 1-Methyl-3-*N-*4-iodophenyl*carbamoyl*-1
Page 1
1,4-Dihydropyridine: synthetic advances, medicinal and insecticidal properties.
A P, Makam P. A P, et al. RSC Adv. 2022 Oct 12;12(45):29253-29290. doi: 10.1039/d2ra04589c. eCollection 2022 Oct 11. RSC Adv. 2022. PMID: 36320730 Free PMC article. Review.
1,4-Dihydropyridine (1,4-DHP) is one of the foremost notable organic scaffolds with diverse pharmaceutical applications. ...
1,4-Dihydropyridine (1,4-DHP) is one of the foremost notable organic scaffolds with diverse pharmaceutical applications. ...
1,4-Dihydropyridine: A Dependable Heterocyclic Ring with the Promising and the Most Anticipable Therapeutic Effects.
Mishra AP, Bajpai A, Rai AK. Mishra AP, et al. Mini Rev Med Chem. 2019;19(15):1219-1254. doi: 10.2174/1389557519666190425184749. Mini Rev Med Chem. 2019. PMID: 31735158 Review.
Nowadays, heterocyclic compounds act as a scaffold and are the backbone of medicinal chemistry. Among all of the heterocyclic scaffolds, 1,4-Dihydropyridine (1,4-DHP) is one of the most important heterocyclic rings that possess prominent therapeutic effects in a ver …
Nowadays, heterocyclic compounds act as a scaffold and are the backbone of medicinal chemistry. Among all of the heterocyclic scaffolds, 1, …
Intramolecular hydrogen bonds in 1,4-dihydropyridine derivatives.
Petrova M, Muhamadejev R, Vigante B, Duburs G, Liepinsh E. Petrova M, et al. R Soc Open Sci. 2018 Jun 13;5(6):180088. doi: 10.1098/rsos.180088. eCollection 2018 Jun. R Soc Open Sci. 2018. PMID: 30110409 Free PMC article.
1,4-Dihydropyridine (1,4-DHP) derivatives have been synthesized and characterized by (1)H, (13)C, (15)N nuclear magnetic resonance (NMR) spectroscopy, secondary proton/deuterium (13)C isotope shifts, variable temperature (1)H NMR experiments and quantum-chemical cal …
1,4-Dihydropyridine (1,4-DHP) derivatives have been synthesized and characterized by (1)H, (13)C, (15)N nuclear magnetic reson …
Comparison between 1,2-Dihydropyridine and 1,4-Dihydropyridine on Hydride-Donating Ability and Activity.
Zhang JY, Zhu XQ. Zhang JY, et al. Molecules. 2022 Aug 24;27(17):5382. doi: 10.3390/molecules27175382. Molecules. 2022. PMID: 36080150 Free PMC article.
In this paper, detailed comparisons of the driving force in thermodynamics and intrinsic force in the kinetics of 1,2-dihydropyridine and 1,4-dihydropyridine isomers of PNAH, HEH, and PYH in hydride transfer reactions are made. ...
In this paper, detailed comparisons of the driving force in thermodynamics and intrinsic force in the kinetics of 1,2-dihydropyridine and 1, …
Inhibitors of Alzheimer's BACE-1 with 3,5-bis-N-(aryl/heteroaryl) carbamoyl-4-aryl-1,4-dihydropyridine structure.
Miri R, Firuzi O, Razzaghi-Asl N, Javidnia K, Edraki N. Miri R, et al. Arch Pharm Res. 2015 Apr;38(4):456-69. doi: 10.1007/s12272-014-0401-x. Epub 2014 Apr 26. Arch Pharm Res. 2015. PMID: 24771353
In the present contribution, a series of new 3,5-bis-N-(aryl/heteroaryl) carbamoyl-4-aryl-1,4-dihydropyridine structures were synthesized as BACE-1 inhibitors (6a-6n). ...
In the present contribution, a series of new 3,5-bis-N-(aryl/heteroaryl) carbamoyl-4-aryl-1,4-dihydropyridine structures were …
An isoxazole strategy for the synthesis of 4-oxo-1,4-dihydropyridine-3-carboxylates.
Zanakhov TO, Galenko EE, Novikov MS, Khlebnikov AF. Zanakhov TO, et al. Beilstein J Org Chem. 2022 Jun 23;18:738-745. doi: 10.3762/bjoc.18.74. eCollection 2022. Beilstein J Org Chem. 2022. PMID: 35821697 Free PMC article.
A method has been developed for the preparation of 2-alkyl-6-aryl-, 2-aryl-6-aryl and 2,6-diaryl-5-aryl/hetaryl-substituted methyl 4-oxo-1,4-dihydropyridine-3-carboxylates by Mo(CO)(6)-mediated ring expansion of methyl 2-(isoxazol-5-yl)-3-oxopropanoates. The high re …
A method has been developed for the preparation of 2-alkyl-6-aryl-, 2-aryl-6-aryl and 2,6-diaryl-5-aryl/hetaryl-substituted methyl 4-oxo-1, …
Synthetic Diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylates Induce Apoptosis.
Ahn S, Lee Y, Park J, Lee J, Shin SY, Lee YH, Koh D, Lim Y. Ahn S, et al. Med Chem. 2018;14(8):851-862. doi: 10.2174/1573406414666180418143048. Med Chem. 2018. PMID: 29669502
BACKGROUND: The Hantzsch ester, diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5- dicarboxylate, has been used as a hydride donor and its various biological effects have been reported. ...CONCLUSION: To obtain chemotherapeutic agents that induce apoptosis, 21 diethyl 2, …
BACKGROUND: The Hantzsch ester, diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5- dicarboxylate, has been used as a hydride donor …
3-Methyl 5-isopropyl 2-methoxyiminomethyl-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate.
Vrábel V, Lehotay J, Oktavec D, Marchalín S. Vrábel V, et al. Acta Crystallogr C. 2001 Sep;57(Pt 9):1073-4. doi: 10.1107/s0108270101009313. Epub 2001 Sep 11. Acta Crystallogr C. 2001. PMID: 11588375
The crystal structure of the title compound, C(20)H(23)N(3)O(7), consists of relatively isolated molecules. The substituted 1,4-dihydropyridine ring adopts a flattened boat conformation. Both ester groups, at positions 3 and 5, have cis,cis geometry. The phenyl ring …
The crystal structure of the title compound, C(20)H(23)N(3)O(7), consists of relatively isolated molecules. The substituted 1,4-di
2,476 results