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1992 3
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Page 1
Effects of 1,4-phenylenebis(methylene)selenocyanate on mutagenesis and p53 protein expression in the tongue of lacI rats treated with 4-nitroquinoline-N-oxide.
Guttenplan J, Chen KM, Khmelnitsky M, Kosinska W, Hennessy J, Bruggeman R, Desai D, Amin S, Sun YW, Spratt TE, El-Bayoumy K. Guttenplan J, et al. Mutat Res. 2007 Dec 1;634(1-2):146-55. doi: 10.1016/j.mrgentox.2007.07.005. Epub 2007 Jul 17. Mutat Res. 2007. PMID: 17720616 Free PMC article.
Previously we showed that the organoselenium compound, 1,4-phenylenebis(methylene)selenocyanate (p-XSC)(1) inhibits 4-nitroquinoline-N-oxide (4-NQO)-induced tongue tumorigenesis in Fisher rats. ...
Previously we showed that the organoselenium compound, 1,4-phenylenebis(methylene)selenocyanate (p-XSC)(1 …
The organoselenium compound 1,4-phenylenebis(methylene)selenocyanate inhibits 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced tumorgenesis and enhances glutathione-related antioxidant levels in A/J mouse lung.
Richie JP Jr, Kleinman W, Desai DH, Das A, Amin SG, Pinto JT, El-Bayoumy K. Richie JP Jr, et al. Chem Biol Interact. 2006 Jun 10;161(2):93-103. doi: 10.1016/j.cbi.2006.03.005. Epub 2006 Mar 12. Chem Biol Interact. 2006. PMID: 16620795
Selenium, in the form of 1,4-phenylenebis(methylene)selenocyanate (p-XSC) but not Se-enriched yeast (Se-yeast), was highly effective at inhibiting lung tumors induced by the tobacco specific nitrosamine (TSNA) 4-(methylnitrosamino)-1-(3-pyridyl) …
Selenium, in the form of 1,4-phenylenebis(methylene)selenocyanate (p-XSC) but not Se-enriched yeast (Se-y …
Antiproliferative effect of 1,4-phenylenebis(methylene)selenocyanate (p-XSC) on colonic epithelium of patients with adenomatous polyps in vitro.
Bartram HP, Krüger S, Dusel G, El-Bayoumy K, Upadhyaya P, Scheppach W. Bartram HP, et al. Eur J Cancer Prev. 2003 Dec;12(6):463-8. doi: 10.1097/00008469-200312000-00004. Eur J Cancer Prev. 2003. PMID: 14639123
We have consistently shown that the organoselenium compound 1,4-phenylenebis(methylene)selenocyanate (p-XSC) is a superior cancer chemopreventive agent and less toxic than selenite or certain naturally-occurring selenoamino acids. ...
We have consistently shown that the organoselenium compound 1,4-phenylenebis(methylene)selenocyanate (p-X …
Comparison of the chemopreventive efficacies of 1,4-phenylenebis(methylene)selenocyanate and selenium-enriched yeast on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced lung tumorigenesis in A/J mouse.
Das A, Desai D, Pittman B, Amin S, El-Bayoumy K. Das A, et al. Nutr Cancer. 2003;46(2):179-85. doi: 10.1207/S15327914NC4602_11. Nutr Cancer. 2003. PMID: 14690794
JAMA 276, 1957, 1996) and assays in laboratory animals provide evidence for a protective role of selenium against the development of several cancers, including lung cancer. We have demonstrated that selenium in the form of 1,4-phenylenebis(methylene) …
JAMA 276, 1957, 1996) and assays in laboratory animals provide evidence for a protective role of selenium against the development of several …
Effects of 1,4-phenylenebis(methylene)selenocyanate (p-XSC) and vitamin E on 4-nitroquinoline-N-oxide (4-NQO)-induced mutagenesis in lacZ mouse upper aerodigestive tissue.
Guttenplan JB, Kosinska W, von Pressentin Md, Rosa J, El-Bayoumy K. Guttenplan JB, et al. Mutat Res. 2002 Jun 27;518(1):85-93. doi: 10.1016/s1383-5718(02)00082-7. Mutat Res. 2002. PMID: 12063070
The effects of dietary administration of 1,4-phenylenebis(methylene)selenocyanate (p-XSC) and Vitamin E on 4-nitroquinoline-N-oxide (4-NQO)-induced mutagenesis in lacZ mouse upper aerodigestive tissues were investigated. 4-NQO was a potent mutag …
The effects of dietary administration of 1,4-phenylenebis(methylene)selenocyanate (p-XSC) and Vitamin E o …
1,4-phenylenebis(methylene)selenocyanate, but not selenomethionine, inhibits androgen receptor and Akt signaling in human prostate cancer cells.
Facompre ND, El-Bayoumy K, Sun YW, Pinto JT, Sinha R. Facompre ND, et al. Cancer Prev Res (Phila). 2010 Aug;3(8):975-84. doi: 10.1158/1940-6207.CAPR-10-0054. Epub 2010 Jul 6. Cancer Prev Res (Phila). 2010. PMID: 20606040 Free PMC article.
Our initial investigations show that the naturally occurring organoselenium compound selenomethionine (SM) and the synthetic 1,4-phenylenebis(methylene)selenocyanate (p-XSC) can inhibit human prostate cancer cell viability; however, in contrast …
Our initial investigations show that the naturally occurring organoselenium compound selenomethionine (SM) and the synthetic 1,4 …
Effects of 1,4-phenylenebis(methylene)selenocyanate, phenethyl isothiocyanate, indole-3-carbinol, and d-limonene individually and in combination on the tumorigenicity of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung.
el-Bayoumy K, Upadhyaya P, Desai DH, Amin S, Hoffmann D, Wynder EL. el-Bayoumy K, et al. Anticancer Res. 1996 Sep-Oct;16(5A):2709-12. Anticancer Res. 1996. PMID: 8917375
In this study we examined whether chemopreventive agents that had each been shown to be effective against lung tuorigenesis induced in A/J mice by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) were more effective when applied together as a "cocktail" than as individual com …
In this study we examined whether chemopreventive agents that had each been shown to be effective against lung tuorigenesis induced in A/J m …
Multiorgan sensitivity to anticarcinogenesis by the organoselenium 1,4-phenylenebis(methylene)selenocyanate.
el-Bayoumy K, Rao CV, Reddy BS. el-Bayoumy K, et al. Nutr Cancer. 2001;40(1):18-27. doi: 10.1207/S15327914NC401_6. Nutr Cancer. 2001. PMID: 11799918 Review.
Synthetic organoselenium compounds can be tailored to achieve greater chemopreventive efficacy with minimal toxic side effects by structural modifications. We demonstrated that 1,4-phenylenebis(methylene)selenocyanate is a powerful chemopreventi …
Synthetic organoselenium compounds can be tailored to achieve greater chemopreventive efficacy with minimal toxic side effects by structural …
The role of apoptosis in the modulation of colon carcinogenesis by dietary fat and by the organoselenium compound 1,4-phenylenebis(methylene)selenocyanate.
Samaha HS, Hamid R, el-Bayoumy K, Rao CV, Reddy BS. Samaha HS, et al. Cancer Epidemiol Biomarkers Prev. 1997 Sep;6(9):699-704. Cancer Epidemiol Biomarkers Prev. 1997. PMID: 9298577
Studies in laboratory animals have demonstrated that dietary supplements of organoselenium, 1,4-phenylenebis(methylene)selenocyanate (p-XSC) inhibit colon carcinogenesis. ...
Studies in laboratory animals have demonstrated that dietary supplements of organoselenium, 1,4-phenylenebis(methyle …
Suppressing effects of dietary supplementation of the organoselenium 1,4-phenylenebis(methylene)selenocyanate and the Citrus antioxidant auraptene on lung metastasis of melanoma cells in mice.
Tanaka T, Kohno H, Murakami M, Kagami S, El-Bayoumy K. Tanaka T, et al. Cancer Res. 2000 Jul 15;60(14):3713-6. Cancer Res. 2000. PMID: 10919638
The modifying effects of the organoselenium 1,4-phenylenebis(methylene)selenocyanate (p-XSC) and the Citrus antioxidant auraptene as dietary supplements on experimental pulmonary metastasis of B16BL6 murine melanoma cells were investigated in an …
The modifying effects of the organoselenium 1,4-phenylenebis(methylene)selenocyanate (p-XSC) and the Citr …
69 results