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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1948 1
1954 1
1955 6
1956 2
1968 3
1969 1
1971 1
1972 2
1973 1
1974 1
1976 6
1977 2
1978 2
1979 2
1980 1
1981 4
1982 3
1983 2
1984 6
1985 6
1986 9
1987 4
1988 7
1989 4
1990 5
1991 10
1992 6
1993 6
1994 6
1995 9
1996 7
1997 4
1998 5
1999 8
2000 14
2001 19
2002 26
2003 27
2004 32
2005 43
2006 41
2007 38
2008 41
2009 39
2010 39
2011 41
2012 44
2013 43
2014 58
2015 51
2016 58
2017 54
2018 44
2019 64
2020 65
2021 75
2022 71
2023 76
2024 32

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1,153 results

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Page 1
A review of the metabolism of 1,4-butanediol diglycidyl ether-crosslinked hyaluronic acid dermal fillers.
De Boulle K, Glogau R, Kono T, Nathan M, Tezel A, Roca-Martinez JX, Paliwal S, Stroumpoulis D. De Boulle K, et al. Dermatol Surg. 2013 Dec;39(12):1758-66. doi: 10.1111/dsu.12301. Epub 2013 Aug 13. Dermatol Surg. 2013. PMID: 23941624 Free PMC article. Review.
Practicing physicians need to be aware of the biological behavior of these products in tissue to enable them to respond to any safety concerns that their patients raise. OBJECTIVES: To provide an overview of the metabolism of 1,4-butanediol diglycidyl ether ( …
Practicing physicians need to be aware of the biological behavior of these products in tissue to enable them to respond to any safety concer …
Busulfan.
[No authors listed] [No authors listed] 2021 Aug 16. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2021 Aug 16. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30000295 Free Books & Documents. Review.
Consequences of 1,4-Butanediol Misuse: A Review.
Skryabin V, Shevtsova Y, Novoselova EA. Skryabin V, et al. Psychopharmacol Bull. 2023 Dec 4;53(4):48-53. Psychopharmacol Bull. 2023. PMID: 38076667 Review.
Gamma-hydroxybutyrate (GHB), along with its precursors, 1,4-butanediol (1,4-BD) and gamma-butyrolactone (GBL), are potent central depressant agents widely illicitly used for their euphoric and relaxant effects. ...
Gamma-hydroxybutyrate (GHB), along with its precursors, 1,4-butanediol (1,4-BD) and gamma-butyrolactone (GBL), are pote …
Gamma-hydroxybutyrate (GHB), 1,4-butanediol (1,4BD), and gamma-butyrolactone (GBL) intoxication: A state-of-the-art review.
Dufayet L, Bargel S, Bonnet A, Boukerma AK, Chevallier C, Evrard M, Guillotin S, Loeuillet E, Paradis C, Pouget AM, Reynoard J, Vaucel JA. Dufayet L, et al. Regul Toxicol Pharmacol. 2023 Aug;142:105435. doi: 10.1016/j.yrtph.2023.105435. Epub 2023 Jun 19. Regul Toxicol Pharmacol. 2023. PMID: 37343712 Review.
gamma-hydroxybutyrate (GHB) is synthesized endogenously from gamma-aminobutyric acid (GABA) or exogenously from 1,4-butanediol (butane-1,4-diol; 1,4-BD) or gamma-butyrolactone (GBL). ...
gamma-hydroxybutyrate (GHB) is synthesized endogenously from gamma-aminobutyric acid (GABA) or exogenously from 1,4-butaned …
Engineering biology for sustainable 1,4-butanediol synthesis.
Trotter CL, Babu GS, Wallace S. Trotter CL, et al. Trends Biotechnol. 2023 Mar;41(3):286-288. doi: 10.1016/j.tibtech.2023.01.006. Epub 2023 Jan 24. Trends Biotechnol. 2023. PMID: 36697283 Free article.
In a landmark paper, Yim et al. utilised an in silico-to-in vivo workflow to enable the high-level bioproduction of the unnatural small molecule 1,4-butanediol in the bacterium Escherichia coli....
In a landmark paper, Yim et al. utilised an in silico-to-in vivo workflow to enable the high-level bioproduction of the unnatural small mole …
Developed and emerging 1,4-butanediol commercial production strategies: forecasting the current status and future possibility.
Kumar P, Park H, Yuk Y, Kim H, Jang J, Pagolu R, Park S, Yeo C, Choi KY. Kumar P, et al. Crit Rev Biotechnol. 2023 Jun 7:1-17. doi: 10.1080/07388551.2023.2176740. Online ahead of print. Crit Rev Biotechnol. 2023. PMID: 37286203 Review.
1,4-Butanediol (1,4-BDO) is a valuable industrial chemical that is primarily produced via several energy-intensive petrochemical processes based on fossil-based raw materials, leading to issues related to: non-renewability, environmental contamination, and hi …
1,4-Butanediol (1,4-BDO) is a valuable industrial chemical that is primarily produced via several energy-intensive petr …
Unraveling 1,4-Butanediol Metabolism in Pseudomonas putida KT2440.
Li WJ, Narancic T, Kenny ST, Niehoff PJ, O'Connor K, Blank LM, Wierckx N. Li WJ, et al. Front Microbiol. 2020 Mar 17;11:382. doi: 10.3389/fmicb.2020.00382. eCollection 2020. Front Microbiol. 2020. PMID: 32256468 Free PMC article.
Genome re-sequencing and proteomic analysis were applied to characterize the genomic and metabolic basis of efficient 1,4-butanediol metabolism. Initially, 1,4-butanediol is oxidized to 4-hydroxybutyrate, in which the highly expressed deh …
Genome re-sequencing and proteomic analysis were applied to characterize the genomic and metabolic basis of efficient 1,4-b …
NTP summary report on the metabolism, disposition, and toxicity of 1,4-butanediol (CAS No. 110-63-4).
Irwin RD. Irwin RD. Toxic Rep Ser. 1996 May;(54):1-28, A1-8, B1-5. Toxic Rep Ser. 1996. PMID: 11803699 Free article. Review.
1,4-Butanediol is an industrial chemical used in the manufacture of other organic chemicals. ...Because the toxicity and carcinogenicity of gamma-hydroxybutyric acid was fully evaluated in the NTP studies of gamma-butyrolactone, and a lack of organ-specific t …
1,4-Butanediol is an industrial chemical used in the manufacture of other organic chemicals. ...Because the toxicity an …
Achievements and Perspectives in 1,4-Butanediol Production from Engineered Microorganisms.
Cheng J, Li J, Zheng L. Cheng J, et al. J Agric Food Chem. 2021 Sep 15;69(36):10480-10485. doi: 10.1021/acs.jafc.1c03769. Epub 2021 Sep 3. J Agric Food Chem. 2021. PMID: 34478293
1,4-Butanediol (1,4-BDO), a significant commodity chemical, is currently manufactured exclusively from a host of energy-intensive processes, accompanied by severe environmental issues, such as the greenhouse effect and air pollution. ...
1,4-Butanediol (1,4-BDO), a significant commodity chemical, is currently manufactured exclusively from a host of energy …
GHB, GBL and 1,4-BD addiction.
Brunt TM, van Amsterdam JG, van den Brink W. Brunt TM, et al. Curr Pharm Des. 2014;20(25):4076-85. doi: 10.2174/13816128113199990624. Curr Pharm Des. 2014. PMID: 24001290 Review.
A growing body of evidence shows that gamma-hydroxybutyric acid (GHB) is an addictive substance. Its precursors gammabutyrolactone (GBL) and 1,4-butanediol (1,4-BD) show the same properties and may pose even more risks due to different pharmacokinetics. ...
A growing body of evidence shows that gamma-hydroxybutyric acid (GHB) is an addictive substance. Its precursors gammabutyrolactone (GBL) and …
1,153 results