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Page 1
A Role for Insulin-like Growth Factor 1 in the Generation of Epileptic Spasms in a murine model.
Ballester-Rosado CJ, Le JT, Lam TT, Mohila CA, Lam S, Anderson AE, Frost JD Jr, Swann JW. Ballester-Rosado CJ, et al. Ann Neurol. 2022 Jul;92(1):45-60. doi: 10.1002/ana.26383. Epub 2022 May 10. Ann Neurol. 2022. PMID: 35467038 Free PMC article.
We used viral injections in neonatal conditional IGF-1R knock-out mice to show that an IGF-1-derived tripeptide (1-3)IGF-1, acts through the IGF-1 receptor to abolish spasms. ...
We used viral injections in neonatal conditional IGF-1R knock-out mice to show that an IGF-1-derived tripeptide (1-3)IGF-1, ac …
Role of peptide-cell surface interactions in cosmetic peptide application.
He B, Wang F, Qu L. He B, et al. Front Pharmacol. 2023 Nov 13;14:1267765. doi: 10.3389/fphar.2023.1267765. eCollection 2023. Front Pharmacol. 2023. PMID: 38027006 Free PMC article.
In this study, we designed two novel targeting peptide motifs to enhance the interaction between cosmetic peptides and the cell surface, thereby improving their performance for skin health. To achieve this, we optimized the well-known peptide tripeptide-1 (GHK) by s …
In this study, we designed two novel targeting peptide motifs to enhance the interaction between cosmetic peptides and the cell surface, the …
Formation of Giant and Small Cyclic Complexes from a Flexible Tripeptide Ligand Controlled by Metal Coordination and Hydrogen Bonds.
Miyake R, Ando A, Ueno M, Muraoka T. Miyake R, et al. J Am Chem Soc. 2019 Jun 5;141(22):8675-8679. doi: 10.1021/jacs.9b01541. Epub 2019 May 16. J Am Chem Soc. 2019. PMID: 31095363 Free article.
Formation of giant cyclic complexes by the assembly of small, flexible units is demonstrated by connecting 14 artificial tripeptides (1) with 14 Ni(II) ions. Although tripeptide 1 is very flexible because of the presence of three CH(2) groups in the main chain, it f …
Formation of giant cyclic complexes by the assembly of small, flexible units is demonstrated by connecting 14 artificial tripeptides (1) wit …
Effects of a Topical Anti-aging Formulation on Skin Aging Biomarkers.
Widgerow AD, Ziegler ME, Garruto JA, Bell M. Widgerow AD, et al. J Clin Aesthet Dermatol. 2022 Aug;15(8):E53-E60. J Clin Aesthet Dermatol. 2022. PMID: 36061477 Free PMC article.
METHODS: Neonatal human fibroblasts were used for telomere length studies to examine the effect of the full RSC formulation and the amino acid components Tripeptide-1 and Hexapeptide-12 (TriHex) on these cellular aging mechanisms. ...
METHODS: Neonatal human fibroblasts were used for telomere length studies to examine the effect of the full RSC formulation and the amino ac …
Rapid and Highly Selective Fluorescent Labeling of Peptides via a Thia-Diels-Alder Cycloaddition: Application to Apelin.
Maujean T, Wagner P, Valencia C, Riché S, Iturrioz X, Villa P, Girard N, Karpenko J, Gulea M, Bonnet D. Maujean T, et al. Bioconjug Chem. 2023 Jan 18;34(1):162-168. doi: 10.1021/acs.bioconjchem.2c00500. Epub 2022 Dec 19. Bioconjug Chem. 2023. PMID: 36534753
Herein, we describe a catalyst-free thia-Diels-Alder cycloaddition for the chemoselective labeling of fully deprotected phosphonodithioester-peptides in solution with fluorophores functionalized with an exocyclic diene. The reaction was optimized on the model tripeptide …
Herein, we describe a catalyst-free thia-Diels-Alder cycloaddition for the chemoselective labeling of fully deprotected phosphonodithioester …
Effect of Peptides on the Synthesis, Properties and Wound Healing Capacity of Silver Nanoparticles.
Papaioannou A, Liakopoulou A, Papoulis D, Gianni E, Gkolfi P, Zygouri E, Letsiou S, Hatziantoniou S. Papaioannou A, et al. Pharmaceutics. 2023 Oct 16;15(10):2471. doi: 10.3390/pharmaceutics15102471. Pharmaceutics. 2023. PMID: 37896231 Free PMC article.
Peptide-silver nanoparticle conjugates were synthesized using myristoyl tetrapeptide 6 (MT6) or copper tripeptide 1 (CuTP1). Peptide-free silver nanoparticles (AgNP) were synthesized using NaBH4 and sodium citrate and were used as control. ...
Peptide-silver nanoparticle conjugates were synthesized using myristoyl tetrapeptide 6 (MT6) or copper tripeptide 1 (CuTP1). P …
Studies on the Design and Synthesis of Marine Peptide Analogues and Their Ability to Promote Proliferation in HUVECs and Zebrafish.
Zheng Y, Tong Y, Wang X, Zhou J, Pang J. Zheng Y, et al. Molecules. 2018 Dec 25;24(1):66. doi: 10.3390/molecules24010066. Molecules. 2018. PMID: 30585208 Free PMC article.
In our previous studies, tripeptide 1 was found to induce angiogenesis in zebrafish embryos and in HUVECs. ...
In our previous studies, tripeptide 1 was found to induce angiogenesis in zebrafish embryos and in HUVECs. ...
QR678 & QR678 Neo Hair Growth Formulations: A Cellular Toxicity & Animal Efficacy Study.
Kapoor R, Shome D, Vadera S, Kumar V, Ram MS. Kapoor R, et al. Plast Reconstr Surg Glob Open. 2020 Aug 25;8(8):e2843. doi: 10.1097/GOX.0000000000002843. eCollection 2020 Aug. Plast Reconstr Surg Glob Open. 2020. PMID: 32983753 Free PMC article.
METHODS: Factors including vascular endothelial growth factor, basic fibroblast growth factor, insulin-like growth factor-1, keratinocyte growth factor, and copper tripeptide 1 (QR 678) or their biomimetic peptides (QR678 Neo) were suspended in a sterile injectable …
METHODS: Factors including vascular endothelial growth factor, basic fibroblast growth factor, insulin-like growth factor-1, keratinocyte gr …
The effect of copper tripeptide and tretinoin on growth factor production in a serum-free fibroblast model.
McCormack MC, Nowak KC, Koch RJ. McCormack MC, et al. Arch Facial Plast Surg. 2001 Jan-Mar;3(1):28-32. Arch Facial Plast Surg. 2001. PMID: 11176716
METHODS: Primary cell lines were established from patient facial skin samples obtained during surgery and plated in serum-free media. At 0 hour, copper tripeptide (1 x 10 (-9) mol/L), tretinoin (1 x 10 (-5) mol/L), or appropriate control vehicle was added. ...
METHODS: Primary cell lines were established from patient facial skin samples obtained during surgery and plated in serum-free media. At 0 h …
A beta-amino acid containing tripeptide from a Pseudomonas-alteromonas bacterium associated with a black sea sponge.
De Rosa S, De Giulio A, Tommonaro G, Popov S, Kujumgiev A. De Rosa S, et al. J Nat Prod. 2000 Oct;63(10):1454-5. doi: 10.1021/np0002132. J Nat Prod. 2000. PMID: 11076579
A novel tripeptide, 1, was isolated from the extracellular extract of a Pseudomonas-Alteromonas bacterium that was associated with the Black Sea sponge Dysidea fragilis. ...
A novel tripeptide, 1, was isolated from the extracellular extract of a Pseudomonas-Alteromonas bacterium that was associated …
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