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The following terms were not found in PubMed: capsaicinyl, hexapeptide-24
Page 1
Did you mean capsaicin succinyl hexapeptide-24 amide (3 results)?
Synthesis and evaluation of succinoyl-caprolactam gamma-secretase inhibitors.
Thompson LA, Liauw AY, Ramanjulu MM, Kasireddy-Polam P, Mercer SE, Maduskuie TP, Glicksman M, Roach AH, Meredith JE, Liu RQ, Combs AP, Higaki JN, Cordell B, Seiffert D, Zaczek RC, Robertson DW, Olson RE. Thompson LA, et al. Bioorg Med Chem Lett. 2006 May 1;16(9):2357-63. doi: 10.1016/j.bmcl.2006.01.055. Epub 2006 Feb 10. Bioorg Med Chem Lett. 2006. PMID: 16473009
The synthesis, evaluation, and structure-activity relationships of a series of succinoyl lactam inhibitors of the Alzheimer's disease gamma-secretase are described. ...
The synthesis, evaluation, and structure-activity relationships of a series of succinoyl lactam inhibitors of the Alzheimer's disease …
Site-specific drug delivery to the middle region of the small intestine by application of enteric coating with hypromellose acetate succinate (HPMCAS).
Tanno FK, Sakuma S, Masaoka Y, Kataoka M, Kozaki T, Kamaguchi R, Ikeda Y, Kokubo H, Yamashita S. Tanno FK, et al. J Pharm Sci. 2008 Jul;97(7):2665-79. doi: 10.1002/jps.21172. J Pharm Sci. 2008. PMID: 17828736
Hypromellose acetate succinate (HPMCAS) with different values of succinoyl group contents was used. Decreasing the succinoyl group content resulted in an increase in the pH at which HPMCAS started to dissolve. ...Similar results were observed in monkey experiments. …
Hypromellose acetate succinate (HPMCAS) with different values of succinoyl group contents was used. Decreasing the succinoyl g …
Solid-phase-assisted synthesis of targeting peptide-PEG-oligo(ethane amino)amides for receptor-mediated gene delivery.
Martin I, Dohmen C, Mas-Moruno C, Troiber C, Kos P, Schaffert D, Lächelt U, Teixidó M, Günther M, Kessler H, Giralt E, Wagner E. Martin I, et al. Org Biomol Chem. 2012 Apr 28;10(16):3258-68. doi: 10.1039/c2ob06907e. Epub 2012 Mar 12. Org Biomol Chem. 2012. PMID: 22407126 Free article.
Here we report on the synthesis of defined polymers containing the following: (i) a plasmid DNA (pDNA) binding domain of eight succinoyl-tetraethylenpentamine (Stp) units and two terminal cysteine residues; (ii) a central polyethylene glycol (PEG) chain (with twenty-four o …
Here we report on the synthesis of defined polymers containing the following: (i) a plasmid DNA (pDNA) binding domain of eight succinoyl …
Fine-tuning of proton sponges by precise diaminoethanes and histidines in pDNA polyplexes.
Lächelt U, Kos P, Mickler FM, Herrmann A, Salcher EE, Rödl W, Badgujar N, Bräuchle C, Wagner E. Lächelt U, et al. Nanomedicine. 2014 Jan;10(1):35-44. doi: 10.1016/j.nano.2013.07.008. Epub 2013 Jul 24. Nanomedicine. 2014. PMID: 23891984
As demonstrated with a sequence-defined library of oligo(ethanamino)amides containing selected oligoethanamino acids and histidines, the total protonation capacity as well as the cationization pH profile within the endolysosomal range have critical impact on gene transfer. …
As demonstrated with a sequence-defined library of oligo(ethanamino)amides containing selected oligoethanamino acids and histidines, …
Correlation of length of linear oligo(ethanamino) amides with gene transfer and cytotoxicity.
Scholz C, Kos P, Leclercq L, Jin X, Cottet H, Wagner E. Scholz C, et al. ChemMedChem. 2014 Sep;9(9):2104-10. doi: 10.1002/cmdc.201300483. Epub 2014 Feb 6. ChemMedChem. 2014. PMID: 24504614
Herein we describe the step-by-step elongation of precise linear oligo(ethanamino) amides by making use of the artificial amino acid succinoyl-tetraethylene pentamine (Stp) for solid-phase-assisted synthesis. ...
Herein we describe the step-by-step elongation of precise linear oligo(ethanamino) amides by making use of the artificial amino acid …
Combination of sequence-defined oligoaminoamides with transferrin-polycation conjugates for receptor-targeted gene delivery.
Zhang W, Rödl W, He D, Döblinger M, Lächelt U, Wagner E. Zhang W, et al. J Gene Med. 2015 Aug-Sep;17(8-9):161-72. doi: 10.1002/jgm.2838. J Gene Med. 2015. PMID: 26227403
The mixed polyplex containing Tf-polycation conjugates and histidinylated 4-arm oligomer with succinoyl tetraethylene pentamine or glutaroyltriethylene tetramine building blocks exhibited the highest gene transfection efficiency in TfR over-expressing human tumour cell lin …
The mixed polyplex containing Tf-polycation conjugates and histidinylated 4-arm oligomer with succinoyl tetraethylene pentamine or gl …
Interfacial interactions of hydrophobic peptides with lipid bilayers.
Reig F, Haro I, Polo D, Egea MA, Alsina MA. Reig F, et al. J Colloid Interface Sci. 2002 Feb 1;246(1):60-9. doi: 10.1006/jcis.2001.8056. J Colloid Interface Sci. 2002. PMID: 16290384
The peptide sequence was YIGSR((NH(2))), and hydrophobic residues linked to the alpha-amino terminal end were decanoyl, myristoyl, stearoyl, and cholesteryl-succinoyl. Before use in biological systems, a physicochemical study was carried out in order to determine their int …
The peptide sequence was YIGSR((NH(2))), and hydrophobic residues linked to the alpha-amino terminal end were decanoyl, myristoyl, stearoyl, …
Nucleotides. LXXIV synthesis of alpha-D-arabino-oligonucleotides.
Henke C, Pfleiderer W. Henke C, et al. Nucleosides Nucleotides Nucleic Acids. 2005;24(10-12):1665-706. doi: 10.1080/15257770500267113. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16438042
The amino groups at the nucleobases and the 2'-hydroxy group at the sugar moiety were protected by the 2-(4-nitro-phenyl)ethoxycarbonyl (npeoc) group (37-40) and the amide function in alpha-araG was additionally blocked by the 2-(4-nitrophenyl)ethyl group (63) to improve s …
The amino groups at the nucleobases and the 2'-hydroxy group at the sugar moiety were protected by the 2-(4-nitro-phenyl)ethoxycarbonyl (npe …
Elucidating spray-dried dispersion dissolution mechanisms with focused beam reflectance measurement: contribution of polymer chemistry and particle properties to performance.
Rawlinson-Malone CF, Ferreira AP, Nicholls D, Nicholson S. Rawlinson-Malone CF, et al. Pharm Dev Technol. 2019 Nov;24(9):1055-1062. doi: 10.1080/10837450.2018.1559189. Epub 2019 Jun 26. Pharm Dev Technol. 2019. PMID: 30640552
There is correlation between FBRM particle count decay rate, representing loss of SDD particles in the dissolution media, and UV dissolution rate, measuring dissolved API. For the SDD formulation examined, the degree of succinoyl substitution for HPMC-AS, SDD particle size …
There is correlation between FBRM particle count decay rate, representing loss of SDD particles in the dissolution media, and UV dissolution …
Inhibitory effect of hydroxypropyl methylcellulose acetate succinate on drug recrystallization from a supersaturated solution assessed using nuclear magnetic resonance measurements.
Ueda K, Higashi K, Yamamoto K, Moribe K. Ueda K, et al. Mol Pharm. 2013 Oct 7;10(10):3801-11. doi: 10.1021/mp400278j. Epub 2013 Sep 26. Mol Pharm. 2013. PMID: 24025080
The cross-peak intensity obtained using NOESY of HF protons with CBZ aromatic protons was greater than that with the amide proton, which indicated that CBZ had hydrophobic interactions with HF in a supersaturated solution. ...In addition, HF appeared to be more hydrophobic …
The cross-peak intensity obtained using NOESY of HF protons with CBZ aromatic protons was greater than that with the amide proton, wh …
12 results