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The moderation of elastase-induced emphysema in the hamster by intratracheal pretreatment or post-treatment with succinyl alanyl alanyl prolyl valine chloromethyl ketone.
Stone PJ, Lucey EC, Calore JD, Snider GL, Franzblau C, Castillo MJ, Powers JC. Stone PJ, et al. Am Rev Respir Dis. 1981 Jul;124(1):56-9. doi: 10.1164/arrd.1981.124.1.56. Am Rev Respir Dis. 1981. PMID: 6911015
The capacity of the synthetic elastase inhibitor, succinyl alanyl alanyl prolyl valine chloromethyl ketone (CMK), to moderate elastase-induced emphysema in hamsters was examined using morphometric and physiologic measurements. ...
The capacity of the synthetic elastase inhibitor, succinyl alanyl alanyl prolyl valine chloromethyl …
Amelioration of human neutrophil elastase-induced emphysema in hamsters by pretreatment with an oligopeptide chloromethyl ketone.
Lucey EC, Stone PJ, Powers JC, Snider GL. Lucey EC, et al. Eur Respir J. 1989 May;2(5):421-7. Eur Respir J. 1989. PMID: 2759224
A study was undertaken to determine whether emphysema, induced in hamsters by intratracheal treatment with human neutrophil elastase (HNE), could be ameliorated by intratracheal instillation of succinyl-alanyl-alanyl-prolyl-valine-chloromethy …
A study was undertaken to determine whether emphysema, induced in hamsters by intratracheal treatment with human neutrophil elastase (HNE), …
Effect of chloromethyl ketone on the progression of elastase-induced emphysema in hamsters.
Lucey EC, Stone PJ. Lucey EC, et al. Am Rev Respir Dis. 1982 Jul;126(1):174-5. doi: 10.1164/arrd.1982.126.1.174. Am Rev Respir Dis. 1982. PMID: 6920251
Intratracheal administration of an elastase inhibitor (Succinyl alanyl alanyl prolyl valine chloromethyl ketone) into hamsters 20 days after induction of emphysema by porcine pancreatic elastase did not affect the lesion seen at 12 …
Intratracheal administration of an elastase inhibitor (Succinyl alanyl alanyl prolyl valine chlorometh …