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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1949 1
1966 2
1970 1
1971 1
1972 4
1973 2
1974 1
1975 7
1976 3
1977 5
1978 4
1979 4
1980 6
1981 6
1982 6
1983 9
1984 11
1985 14
1986 10
1987 10
1988 11
1989 9
1990 11
1991 16
1992 9
1993 14
1994 20
1995 9
1996 14
1997 9
1998 8
1999 12
2000 13
2001 17
2002 14
2003 25
2004 26
2005 19
2006 28
2007 25
2008 22
2009 29
2010 38
2011 41
2012 51
2013 41
2014 46
2015 41
2016 50
2017 45
2018 42
2019 50
2020 40
2021 34
2022 34
2023 29
2024 13

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972 results

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Page 1
Efficacy of polyarginine peptides in the treatment of stroke: A systematic review and meta-analysis.
Tahmasbi F, Madani Neishaboori A, Mardani M, Toloui A, Komlakh K, Azizi Y, Yousefifard M. Tahmasbi F, et al. Brain Behav. 2023 Jan;13(1):e2858. doi: 10.1002/brb3.2858. Epub 2022 Dec 21. Brain Behav. 2023. PMID: 36542540 Free PMC article. Review.
BACKGROUND: Disparities exist regarding an efficient treatment for stroke. Polyarginines have shown promising neuroprotective properties based on available published studies. ...Inclusion criteria were administrating polyarginine peptides in stroke animal models. Ex …
BACKGROUND: Disparities exist regarding an efficient treatment for stroke. Polyarginines have shown promising neuroprotective propert …
Polyarginine Cell-Penetrating Peptides Bind and Inhibit SERCA2.
Lunde PK, Manfra O, Støle TP, Lunde M, Martinsen M, Carlson CR, Louch WE. Lunde PK, et al. Cells. 2023 Sep 26;12(19):2358. doi: 10.3390/cells12192358. Cells. 2023. PMID: 37830576 Free PMC article.
We presently investigated whether the commonly used CPPs TAT and the polyarginines Arg(9) and Arg(11) exert off-target effects on cellular Ca(2+) homeostasis. ...Experiments in HEK cells overexpressing individual SERCA isoforms confirmed that polyarginine incubation …
We presently investigated whether the commonly used CPPs TAT and the polyarginines Arg(9) and Arg(11) exert off-target effects on cel …
Protein Therapy: in vivo protein transduction by polyarginine (11R) PTD and subcellular targeting delivery.
Matsui H, Tomizawa K, Lu YF, Matsushita M. Matsui H, et al. Curr Protein Pept Sci. 2003 Apr;4(2):151-7. doi: 10.2174/1389203033487270. Curr Protein Pept Sci. 2003. PMID: 12678854 Review.
Protein Therapy is a newly developed method, which allows proteins, peptides and biologically active compounds to penetrate across the plasma membrane of eukaryotic cells by a polyarginine (most efficiently by 11-arginine, 11R) protein transduction domain. ...
Protein Therapy is a newly developed method, which allows proteins, peptides and biologically active compounds to penetrate across the plasm …
Polyarginine induces an antitumor immune response through binding to toll-like receptor 4.
Yang Y, Wolfram J, Fang X, Shen H, Ferrari M. Yang Y, et al. Small. 2014 Apr 9;10(7):1250-4. doi: 10.1002/smll.201302887. Epub 2013 Dec 10. Small. 2014. PMID: 24323884 Free PMC article.
A novel function of polyarginine as an activator of the immune system is reported. Single-molecule fluorescence imaging and single-molecule force measurements demonstrate that polyarginine binds specifically to the toll-like receptor 4 (TLR4), inducing receptor dime …
A novel function of polyarginine as an activator of the immune system is reported. Single-molecule fluorescence imaging and single-mo …
Computational Study of Complex Formation between Hyaluronan Polymers and Polyarginine Peptides at Various Ratios.
Kulik N, Minofar B, Jugl A, Pekař M. Kulik N, et al. Langmuir. 2023 Oct 10;39(40):14212-14222. doi: 10.1021/acs.langmuir.3c01318. Epub 2023 Sep 29. Langmuir. 2023. PMID: 37773978 Free PMC article.
Among these macromolecules, positively charged arginine molecules or polyarginine peptides demonstrate potential in drug delivery when complexed with hyaluronan. This study aimed to compare and elucidate the results of both experimental and computational investigations on …
Among these macromolecules, positively charged arginine molecules or polyarginine peptides demonstrate potential in drug delivery whe …
Cell-penetrating peptides and proteins: new inhibitors of allergic airways disease.
Kinyanjui MW, Fixman ED. Kinyanjui MW, et al. Can J Physiol Pharmacol. 2008 Jan-Feb;86(1-2):1-7. doi: 10.1139/y07-125. Can J Physiol Pharmacol. 2008. PMID: 18418441 Review.
Several naturally occurring PTDs, including those from HIV TAT and Drosophila antennapedia, have this unique activity. Synthetic CPPs, such as polyarginine, also have the ability to enter cells and transport a variety of cargo. ...
Several naturally occurring PTDs, including those from HIV TAT and Drosophila antennapedia, have this unique activity. Synthetic CPPs, such …
Cell-penetrating properties of the transactivator of transcription and polyarginine (R9) peptides, their conjugative effect on nanoparticles and the prospect of conjugation with arsenic trioxide.
Kanwar JR, Gibbons J, Verma AK, Kanwar RK. Kanwar JR, et al. Anticancer Drugs. 2012 Jun;23(5):471-82. doi: 10.1097/CAD.0b013e32835065ed. Anticancer Drugs. 2012. PMID: 22241171 Review.
The mechanism of action is still a highly debated subject among researchers; it seems that a commonality between all CPPs is the presence of positively charged residues within the amino acid chain. Polyarginine and the transactivator of transcription peptide are two widely …
The mechanism of action is still a highly debated subject among researchers; it seems that a commonality between all CPPs is the presence of …
972 results