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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1959 8
1960 18
1961 14
1962 16
1963 47
1964 50
1965 47
1966 33
1967 40
1968 37
1969 37
1970 20
1971 25
1972 26
1973 33
1974 27
1975 13
1976 19
1977 22
1978 33
1979 27
1980 19
1981 30
1982 44
1983 41
1984 49
1985 47
1986 47
1987 73
1988 57
1989 45
1990 37
1991 47
1992 38
1993 42
1994 29
1995 32
1996 25
1997 24
1998 23
1999 27
2000 17
2001 20
2002 14
2003 13
2004 10
2005 13
2006 22
2007 19
2008 11
2009 14
2010 14
2011 13
2012 15
2013 16
2014 12
2015 11
2016 14
2017 15
2018 18
2019 14
2020 19
2021 18
2022 11
2023 18
2024 6

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1,697 results

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Page 1
Phenelzine and Morphine Drug-Drug Interaction? A Literature Review.
Beechinor RJ, Tyson R, Roth ME. Beechinor RJ, et al. J Pharm Pract. 2021 Oct;34(5):818-823. doi: 10.1177/0897190020970752. Epub 2020 Dec 3. J Pharm Pract. 2021. PMID: 33267714 Review.
The objectives of this manuscript are to describe a case report of a patient whose phenelzine maintenance therapy was discontinued due to concern for a phenelzine-morphine drug interaction, to review the available literature regarding the potential for this drug-dru …
The objectives of this manuscript are to describe a case report of a patient whose phenelzine maintenance therapy was discontinued du …
Classics in Chemical Neuroscience: Selegiline, Isocarboxazid, Phenelzine, and Tranylcypromine.
Hoffman GR, Olson MG, Schoffstall AM, Estévez RF, Van den Eynde V, Gillman PK, Stabio ME. Hoffman GR, et al. ACS Chem Neurosci. 2023 Dec 6;14(23):4064-4075. doi: 10.1021/acschemneuro.3c00591. Epub 2023 Nov 15. ACS Chem Neurosci. 2023. PMID: 37966854 Review.
It is therefore timely to review key aspects of the four "classic" MAOIs: high-dose selegiline, isocarboxazid, phenelzine, and tranylcypromine. This review discusses their chemical synthesis, metabolism, pharmacology, adverse effects, and the history and importance of thes …
It is therefore timely to review key aspects of the four "classic" MAOIs: high-dose selegiline, isocarboxazid, phenelzine, and tranyl …
Overview of the Neuroprotective Effects of the MAO-Inhibiting Antidepressant Phenelzine.
Matveychuk D, MacKenzie EM, Kumpula D, Song MS, Holt A, Kar S, Todd KG, Wood PL, Baker GB. Matveychuk D, et al. Cell Mol Neurobiol. 2022 Jan;42(1):225-242. doi: 10.1007/s10571-021-01078-3. Epub 2021 Apr 10. Cell Mol Neurobiol. 2022. PMID: 33839994 Free PMC article. Review.
Phenelzine (PLZ) is a monoamine oxidase (MAO)-inhibiting antidepressant with anxiolytic properties. ...
Phenelzine (PLZ) is a monoamine oxidase (MAO)-inhibiting antidepressant with anxiolytic properties. ...
[Phenelzine: legacy or current psychiatric practice?].
Marini S, Serata D, Brugnoli R. Marini S, et al. Clin Ter. 2013 May-Jun;164(3):e211-22. doi: 10.7417/CT.2013.1571. Clin Ter. 2013. PMID: 23868641 Review. Italian.
Monoamine oxidase inhibitors (MAO-I) are the first drugs of antidepressant classes discovered. Phenelzine is a worldwide prescribed MAO-I, studied in a variety of mood and anxiety disorders. ...We performed a careful PubMed (1980-2012) search on clinical pharmacology and c …
Monoamine oxidase inhibitors (MAO-I) are the first drugs of antidepressant classes discovered. Phenelzine is a worldwide prescribed M …
Phenelzine discontinuation: A bitter pill to swallow.
Smith L, Siskind D. Smith L, et al. Aust N Z J Psychiatry. 2021 Aug;55(8):831-832. doi: 10.1177/0004867420965700. Epub 2020 Oct 10. Aust N Z J Psychiatry. 2021. PMID: 33040569 No abstract available.
Attenuation of the effects of oxidative stress by the MAO-inhibiting antidepressant and carbonyl scavenger phenelzine.
Baker G, Matveychuk D, MacKenzie EM, Holt A, Wang Y, Kar S. Baker G, et al. Chem Biol Interact. 2019 May 1;304:139-147. doi: 10.1016/j.cbi.2019.03.003. Epub 2019 Mar 8. Chem Biol Interact. 2019. PMID: 30857888 Free article. Review.
Phenelzine (beta-phenylethylhydrazine) is a monoamine oxidase (MAO)-inhibiting antidepressant with anxiolytic properties. ...In PC12 cells treated with the neurotoxin MPP(+), phenelzine has been reported to reduce several adverse effects of MPP(+). ...
Phenelzine (beta-phenylethylhydrazine) is a monoamine oxidase (MAO)-inhibiting antidepressant with anxiolytic properties. ...In PC12 …
Phenelzine-based probes reveal Secernin-3 is involved in thermal nociception.
Bustin KA, Shishikura K, Chen I, Lin Z, McKnight N, Chang Y, Wang X, Li JJ, Arellano E, Pei L, Morton PD, Gregus AM, Buczynski MW, Matthews ML. Bustin KA, et al. Mol Cell Neurosci. 2023 Jun;125:103842. doi: 10.1016/j.mcn.2023.103842. Epub 2023 Mar 15. Mol Cell Neurosci. 2023. PMID: 36924917
Here, we applied our activity-based proteomics discovery platform to map non-encoded and post-translationally acquired enzyme functionalities (e.g. cofactors) in vivo using chemical probes that exploit the nucleophilic hydrazine pharmacophores found in a classic antidepressant dr …
Here, we applied our activity-based proteomics discovery platform to map non-encoded and post-translationally acquired enzyme functionalitie …
Phenelzine, imipramine, and placebo in borderline patients meeting criteria for atypical depression.
Parsons B, Quitkin FM, McGrath PJ, Stewart JW, Tricamo E, Ocepek-Welikson K, Harrison W, Rabkin JG, Wager SG, Nunes E. Parsons B, et al. Psychopharmacol Bull. 1989;25(4):524-34. Psychopharmacol Bull. 1989. PMID: 2698483 Review.
Although some patients with atypical depression who meet borderline criteria will improve with tricyclic therapy, a significantly greater proportion will improve with the monoamine oxidase inhibitor (MAOI), phenelzine....
Although some patients with atypical depression who meet borderline criteria will improve with tricyclic therapy, a significantly greater pr …
Phenelzine protects against acetaminophen induced apoptosis in HepG2 cells.
Tüylü Küçükkılınç T, Ercan A. Tüylü Küçükkılınç T, et al. Drug Chem Toxicol. 2024 Jan;47(1):81-89. doi: 10.1080/01480545.2023.2217696. Epub 2023 May 29. Drug Chem Toxicol. 2024. PMID: 37246945
However, phenelzine had minimal effect on NO and GSH levels and did not alleviate ER stress. Pathway enrichment analysis revealed a potential connection between APAP toxicity and phenelzine metabolism. These findings suggested that phenelzine's protective eff …
However, phenelzine had minimal effect on NO and GSH levels and did not alleviate ER stress. Pathway enrichment analysis revealed a p …
Phenelzine poisoning.
Breheny FX, Dobb GJ, Clarke GM. Breheny FX, et al. Anaesthesia. 1986 Jan;41(1):53-6. doi: 10.1111/j.1365-2044.1986.tb12704.x. Anaesthesia. 1986. PMID: 2868672 Free article.
A 46-year-old female with severe phenelzine poisoning was managed successfully by alpha blockade and fluid loading, with the aid of invasive haemodynamic monitoring. ...
A 46-year-old female with severe phenelzine poisoning was managed successfully by alpha blockade and fluid loading, with the aid of i …
1,697 results