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Page 1
Overview of medically important antifungal azole derivatives.
Fromtling RA. Fromtling RA. Clin Microbiol Rev. 1988 Apr;1(2):187-217. doi: 10.1128/CMR.1.2.187. Clin Microbiol Rev. 1988. PMID: 3069196 Free PMC article. Review.
Included are historical and state of the art information on the in vitro activity, experimental in vivo activity, mode of action, pharmacokinetics, clinical studies, and uses and adverse reactions of imidazoles currently marketed (clotrimazole, miconazole, econazole, ketoconazole …
Included are historical and state of the art information on the in vitro activity, experimental in vivo activity, mode of action, pharmacoki …
Synthesis and biological evaluation of vinyl ether-containing azole derivatives as inhibitors of Trichophyton rubrum.
Wang L, Yang W, Wang K, Zhu J, Shen F, Hu Y. Wang L, et al. Bioorg Med Chem Lett. 2012 Jul 15;22(14):4887-90. doi: 10.1016/j.bmcl.2012.05.070. Epub 2012 May 24. Bioorg Med Chem Lett. 2012. PMID: 22683344
In comparison with fluconazole, itraconazole, voriconazole, omoconazole and amphotericin B, several compounds (such as 7d, 7g and 7h) exhibited more potent inhibitory activities, suggesting that they were promising leads for the development of novel antifungal agents....
In comparison with fluconazole, itraconazole, voriconazole, omoconazole and amphotericin B, several compounds (such as 7d, 7g and 7h) …
Therapeutic effects of omoconazole nitrate on guinea-pigs experimentally infected with Trichophyton mentagrophytes.
Itoyama T, Uchida K, Yamaguchi H. Itoyama T, et al. J Antimicrob Chemother. 1997 Jun;39(6):825-7. doi: 10.1093/jac/39.6.825. J Antimicrob Chemother. 1997. PMID: 9222056
The therapeutic effects of topical omoconazole nitrate (OMZ) on Trichophyton mentagrophytes-infected guinea-pigs were investigated. ...
The therapeutic effects of topical omoconazole nitrate (OMZ) on Trichophyton mentagrophytes-infected guinea-pigs were investigated. . …
Study of the effective dose of a topical antifungal agent, omoconazole nitrate, on the basis of percutaneous pharmacokinetics in guinea-pigs and mice.
Hashiguchi T, Ryu A, Itoyama T, Uchida K, Yamaguchi H. Hashiguchi T, et al. J Pharm Pharmacol. 1997 Aug;49(8):757-61. doi: 10.1111/j.2042-7158.1997.tb06107.x. J Pharm Pharmacol. 1997. PMID: 9379351
Creams containing omoconazole nitrate were prepared on a pilot basis. The therapeutic effect of the omoconazole nitrate creams was examined in an in-vivo pharmacological dermatophytosis infection model in guinea-pigs. Creams containing 0.25% or higher concentrations …
Creams containing omoconazole nitrate were prepared on a pilot basis. The therapeutic effect of the omoconazole nitrate creams …
Therapeutic effects of omoconazole nitrate on experimental tinea pedis, an intractable dermatophytosis, in guinea-pigs.
Itoyama T, Uchida K, Yamaguchi H, Fujita S. Itoyama T, et al. J Antimicrob Chemother. 1997 Sep;40(3):441-4. doi: 10.1093/jac/40.3.441. J Antimicrob Chemother. 1997. PMID: 9338501
Treatment with omoconazole nitrate cream was started on week 2 postinfection and continued for 3 or 4 weeks. ...This result suggests that omoconazole nitrate has a potential usefulness for the treatment of tinea pedis in humans....
Treatment with omoconazole nitrate cream was started on week 2 postinfection and continued for 3 or 4 weeks. ...This result suggests …
Imidazolylchromanones containing non-benzylic oxime ethers: synthesis and molecular modeling study of new azole antifungals selective against Cryptococcus gattii.
Babazadeh-Qazijahani M, Badali H, Irannejad H, Afsarian MH, Emami S. Babazadeh-Qazijahani M, et al. Eur J Med Chem. 2014 Apr 9;76:264-73. doi: 10.1016/j.ejmech.2014.02.019. Epub 2014 Feb 11. Eur J Med Chem. 2014. PMID: 24583607
A series of imidazolylchromanone oximes containing phenoxyethyl ether moiety, as found in omoconazole, were synthesized and evaluated against yeasts (Candida albicans and Cryptococcus gattii) and filamentous fungi (Aspergillus fumigatus and Exophiala dermatitidis). ...
A series of imidazolylchromanone oximes containing phenoxyethyl ether moiety, as found in omoconazole, were synthesized and evaluated …
Ultrastructural alterations of Candida albicans induced by a new imidazole antimycotic omoconazole nitrate.
Nishiyama Y, Itoyama T, Yamaguchi H. Nishiyama Y, et al. Microbiol Immunol. 1997;41(5):395-402. doi: 10.1111/j.1348-0421.1997.tb01870.x. Microbiol Immunol. 1997. PMID: 9194038 Free article.
The antifungal effects of an imidazole-antimycotic omoconazole nitrate (OMZ) on the morphology and ultrastructure of Candida albicans yeast cells were studied using scanning and transmission electron microscopy. ...
The antifungal effects of an imidazole-antimycotic omoconazole nitrate (OMZ) on the morphology and ultrastructure of Candida albicans …
[In vitro antifungal activity of omoconazole nitrate, a novel imidazone antimycotic drug, against clinical isolates from patients with cutaneous mycosis].
Uchida K, Itoyama T, Yamaguchi H. Uchida K, et al. Jpn J Antibiot. 1996 Aug;49(8):818-23. Jpn J Antibiot. 1996. PMID: 9053537 Japanese.
In vitro antifungal activities of omoconazole nitrate (OMZ), a novel antifungal imidazole antimycotic drug, are examined against clinical isolates obtained from patients with cutaneous mycosis and its activity was compared with that of bifonazole (BFZ). ...
In vitro antifungal activities of omoconazole nitrate (OMZ), a novel antifungal imidazole antimycotic drug, are examined against clin …
[In vitro antifungal activity of omoconazole nitrate, a new imidazole antimycotic].
Itoyama T, Aoki Y, Hiratani T, Uchida K, Yamaguchi H. Itoyama T, et al. Jpn J Antibiot. 1993 Sep;46(9):773-80. Jpn J Antibiot. 1993. PMID: 8254897 Japanese.
In vitro antifungal activities of omoconazole nitrate (OMZ), a new topical imidazole antifungal agent, were studied against 364 strains of 22 genera and 47 species of stock cultures of a wide range of medically important fungi. ...
In vitro antifungal activities of omoconazole nitrate (OMZ), a new topical imidazole antifungal agent, were studied against 364 strai …
14 results