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2006 2
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Mirtoselect, an anthocyanin-rich bilberry extract, attenuates non-alcoholic steatohepatitis and associated fibrosis in ApoE()3Leiden mice.
Morrison MC, Liang W, Mulder P, Verschuren L, Pieterman E, Toet K, Heeringa P, Wielinga PY, Kooistra T, Kleemann R. Morrison MC, et al. J Hepatol. 2015 May;62(5):1180-6. doi: 10.1016/j.jhep.2014.12.011. Epub 2014 Dec 13. J Hepatol. 2015. PMID: 25514555 Free article.
Therefore, we studied the effects of the standardised anthocyanin-rich extract Mirtoselect on diet-induced NASH in a translational model of disease. ...Mirtoselect significantly reduced accumulation and crystallisation of intrahepatic free cholesterol, providing a p …
Therefore, we studied the effects of the standardised anthocyanin-rich extract Mirtoselect on diet-induced NASH in a translational mo …
The effect of a natural, standardized bilberry extract (Mirtoselect) in dry eye: a randomized, double blinded, placebo-controlled trial.
Riva A, Togni S, Franceschi F, Kawada S, Inaba Y, Eggenhoffner R, Giacomelli L. Riva A, et al. Eur Rev Med Pharmacol Sci. 2017 May;21(10):2518-2525. Eur Rev Med Pharmacol Sci. 2017. PMID: 28617532 Free article.
RESULTS: The area under the curve of plasmatic levels of anthocyanosides in rats resulted 202.3424.23 g.min/ml for Mirtoselect and 130.934.93 g.min/ml for the highly purified anthocyanin-rich bilberry extract, notwithstanding the fact that the highly purified anthocyanin-r …
RESULTS: The area under the curve of plasmatic levels of anthocyanosides in rats resulted 202.3424.23 g.min/ml for Mirtoselect and 13 …
Anthocyans as tertiary chemopreventive agents in bladder cancer: anti-oxidant mechanisms and interaction with mitomycin C.
Higgins JA, Zainol M, Brown K, Jones GD. Higgins JA, et al. Mutagenesis. 2014 Jul;29(4):227-35. doi: 10.1093/mutage/geu009. Epub 2014 Apr 17. Mutagenesis. 2014. PMID: 24743948
Investigations into the possible protective mechanisms associated with these anti-oxidant properties revealed that mirtoselect chelates metal ions. In mirtoselect/MMC combination studies, no adverse effects on measures of DNA damage were observed compared to treatme …
Investigations into the possible protective mechanisms associated with these anti-oxidant properties revealed that mirtoselect chelat …
Effect of cyanidin-3-glucoside and an anthocyanin mixture from bilberry on adenoma development in the ApcMin mouse model of intestinal carcinogenesis--relationship with tissue anthocyanin levels.
Cooke D, Schwarz M, Boocock D, Winterhalter P, Steward WP, Gescher AJ, Marczylo TH. Cooke D, et al. Int J Cancer. 2006 Nov 1;119(9):2213-20. doi: 10.1002/ijc.22090. Int J Cancer. 2006. PMID: 16823841 Free article.
Apc(Min) mice ingested C3G or Mirtoselect at 0.03, 0.1 or 0.3% in the diet for 12 weeks, and intestinal adenomas were counted. ...The efficacy of C3G and Mirtoselect in the Apc(Min) mouse renders the further development of anthocyanins as potential human colorectal …
Apc(Min) mice ingested C3G or Mirtoselect at 0.03, 0.1 or 0.3% in the diet for 12 weeks, and intestinal adenomas were counted. ...The …
Bilberry extracts are not created equal: the role of non anthocyanin fraction. Discovering the "dark side of the force" in a preliminary study.
Gizzi C, Belcaro G, Gizzi G, Feragalli B, Dugall M, Luzzi R, Cornelli U. Gizzi C, et al. Eur Rev Med Pharmacol Sci. 2016 Jun;20(11):2418-24. Eur Rev Med Pharmacol Sci. 2016. PMID: 27338070 Free article.
RESULTS: Overall, significant improvements in several retinal circulatory parameters such as retinal blood flow velocity, with respect to the values at inclusion, were observed in both supplementation groups, especially in Mirtoselect supplementation group. However, at 6 m …
RESULTS: Overall, significant improvements in several retinal circulatory parameters such as retinal blood flow velocity, with respect to th …
Development of analyses by high-performance liquid chromatography and liquid chromatography/tandem mass spectrometry of bilberry (Vaccinium myrtilus) anthocyanins in human plasma and urine.
Cooke DN, Thomasset S, Boocock DJ, Schwarz M, Winterhalter P, Steward WP, Gescher AJ, Marczylo TH. Cooke DN, et al. J Agric Food Chem. 2006 Sep 20;54(19):7009-13. doi: 10.1021/jf061562q. J Agric Food Chem. 2006. PMID: 16968056
Intra- and interday variations for C3G extraction were 9 and 9.1% in plasma and 7.1 and 9.1% in urine and were less than 15% for all anthocyanins from a standardized bilberry extract (mirtoselect). Analysis of mirtoselect by HPLC with UV detection produced spectra w …
Intra- and interday variations for C3G extraction were 9 and 9.1% in plasma and 7.1 and 9.1% in urine and were less than 15% for all anthocy …
Determination of anthocyanins in the urine of patients with colorectal liver metastases after administration of bilberry extract.
Cai H, Thomasset SC, P-Berry D, Garcea G, Brown K, Steward WP, Gescher AJ. Cai H, et al. Biomed Chromatogr. 2011 Jun;25(6):660-3. doi: 10.1002/bmc.1499. Epub 2010 Aug 31. Biomed Chromatogr. 2011. PMID: 20812200
They received a single dose of 1.88 g standardized bilberry extract (mirtoselect) via either nasogastric or nasojejunal tube intra-operatively during liver resection. HPLC-MS/MS and HPLC-UV analysis showed there were more anthocyanins and metabolites in the urine of the pa …
They received a single dose of 1.88 g standardized bilberry extract (mirtoselect) via either nasogastric or nasojejunal tube intra-op …
Mirtogenol® supplementation in association with dorzolamide-timolol or latanoprost improves the retinal microcirculation in asymptomatic patients with increased ocular pressure.
Gizzi C, Torino-Rodriguez P, Belcaro G, Hu S, Hosoi M, Feragalli B. Gizzi C, et al. Eur Rev Med Pharmacol Sci. 2017 Oct;21(20):4720-4725. Eur Rev Med Pharmacol Sci. 2017. PMID: 29131240 Free article.
Oral supplementation consisted of two tablets/day of Mirtogenol (80 mg of bilberry extract, Mirtoselect plus 40 mg of Pycnogenol). IOP, retinal blood flow, perfusion of the circle of Zinn-Haller, and oxidative stress were measured during the registry period. ...
Oral supplementation consisted of two tablets/day of Mirtogenol (80 mg of bilberry extract, Mirtoselect plus 40 mg of Pycnogenol). IO …
Pharmacokinetic profile of bilberry anthocyanins in rats and the role of glucose transporters: LC-MS/MS and computational studies.
Baron G, Altomare A, Regazzoni L, Redaelli V, Grandi S, Riva A, Morazzoni P, Mazzolari A, Carini M, Vistoli G, Aldini G. Baron G, et al. J Pharm Biomed Anal. 2017 Sep 10;144:112-121. doi: 10.1016/j.jpba.2017.04.042. Epub 2017 Apr 27. J Pharm Biomed Anal. 2017. PMID: 28499643
In particular, the absorption of 15 different anthocyanins contained in a standardized bilberry extract (Mirtoselect()) was measured in rats by a validated LC-ESI-MS/MS approach. ...
In particular, the absorption of 15 different anthocyanins contained in a standardized bilberry extract (Mirtoselect()) was measured …
13 results