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Page 1
Biosynthesis of marcfortine A.
Kuo MS, Wiley VH, Cialdella JI, Yurek DA, Whaley HA, Marshall VP. Kuo MS, et al. J Antibiot (Tokyo). 1996 Oct;49(10):1006-13. doi: 10.7164/antibiotics.49.1006. J Antibiot (Tokyo). 1996. PMID: 8968394 Free article.
This report describes the results of a biosynthesis study of marcfortine A (MA). We report here that MA is derived from methionine, tryptophan, lysine and two isoprene units, the latter two being derived from acetic acid. ...
This report describes the results of a biosynthesis study of marcfortine A (MA). We report here that MA is derived from methio …
Marcfortine and paraherquamide class of anthelmintics: discovery of PNU-141962.
Lee BH, Clothier MF, Dutton FE, Nelson SJ, Johnson SS, Thompson DP, Geary TG, Whaley HD, Haber CL, Marshall VP, Kornis GI, McNally PL, Ciadella JI, Martin DG, Bowman JW, Baker CA, Coscarelli EM, Alexander-Bowman SJ, Davis JP, Zinser EW, Wiley V, Lipton MF, Mauragis MA. Lee BH, et al. Curr Top Med Chem. 2002 Jul;2(7):779-93. doi: 10.2174/1568026023393705. Curr Top Med Chem. 2002. PMID: 12052190 Review.
Chemically the two compounds differ only in one ring; in marcfortine A, ring G is six-membered and carries no substituents, while in paraherquamide A, ring G is five-membered with methyl and hydroxyl substituents at C14. Paraherquamide A (2) is superior to marcfo …
Chemically the two compounds differ only in one ring; in marcfortine A, ring G is six-membered and carries no substituents, wh …
Aspergillicins A-E: five novel depsipeptides from the marine-derived fungus Aspergillus carneus.
Capon RJ, Skene C, Stewart M, Ford J, O'Hair RA, Williams L, Lacey E, Gill JH, Heiland K, Friedel T. Capon RJ, et al. Org Biomol Chem. 2003 Jun 7;1(11):1856-62. doi: 10.1039/b302306k. Org Biomol Chem. 2003. PMID: 12945765
A search for new antiparasitic agents from a strain of the fungus Aspergillus carneus isolated from an estuarine sediment collected in Tasmania, Australia, yielded the known terrestrial fungal metabolite marcfortine A (1) as an exceptionally potent antiparasitic age …
A search for new antiparasitic agents from a strain of the fungus Aspergillus carneus isolated from an estuarine sediment collected in Tasma …
Fungal species and mycotoxins in mouldy spots of grass and maize silages in Austria.
Penagos-Tabares F, Khiaosa-Ard R, Schmidt M, Pacífico C, Faas J, Jenkins T, Nagl V, Sulyok M, Labuda R, Zebeli Q. Penagos-Tabares F, et al. Mycotoxin Res. 2022 May;38(2):117-136. doi: 10.1007/s12550-022-00453-3. Epub 2022 Mar 26. Mycotoxin Res. 2022. PMID: 35347677 Free PMC article.
The presence of complex mixtures of toxic and potentially toxic compounds was evidenced by high levels and occurrences ( 50%) of Penicillium-produced compounds such as mycophenolic acid (MPA), roquefortines (ROCs), andrastins (ANDs) and marcfortine A. Mouldy silages …
The presence of complex mixtures of toxic and potentially toxic compounds was evidenced by high levels and occurrences ( 50%) of Penicillium …
C24 and C25 substituted marcfortine A derivatives.
Lee BH, Clothier MF. Lee BH, et al. Bioorg Med Chem Lett. 1998 Dec 1;8(23):3415-8. doi: 10.1016/s0960-894x(98)00615-5. Bioorg Med Chem Lett. 1998. PMID: 9873744
The dioxepinoindole ring found in marcfortine A (1) is unique among natural products. In order to determine the importance of the substitution pattern of the C24-C25 olefin, we synthesized a variety of analogs at these positions. ...
The dioxepinoindole ring found in marcfortine A (1) is unique among natural products. In order to determine the importance of …
Mycotoxins and other secondary metabolites produced in vitro by Penicillium paneum Frisvad and Penicillium roqueforti Thom isolated from baled grass silage in Ireland.
O'Brien M, Nielsen KF, O'Kiely P, Forristal PD, Fuller HT, Frisvad JC. O'Brien M, et al. J Agric Food Chem. 2006 Nov 29;54(24):9268-76. doi: 10.1021/jf0621018. J Agric Food Chem. 2006. PMID: 17117820
The findings mostly agreed with the literature, although some metabolites were not consistently produced by either fungus. Roquefortine C, marcfortine A, and andrastin A were consistently produced, whereas PR toxin and patulin were not. Five silage samples were scre …
The findings mostly agreed with the literature, although some metabolites were not consistently produced by either fungus. Roquefortine C, …
Multi-mycotoxin analysis of maize silage by LC-MS/MS.
Rasmussen RR, Storm IM, Rasmussen PH, Smedsgaard J, Nielsen KF. Rasmussen RR, et al. Anal Bioanal Chem. 2010 May;397(2):765-76. doi: 10.1007/s00216-010-3545-7. Epub 2010 Mar 6. Anal Bioanal Chem. 2010. PMID: 20213172 Free article.
The method was applied to 20 selected silage samples and alternariol monomethyl ether, andrastin A, alternariol, citreoisocoumarin, deoxynivalenol, enniatin B, fumigaclavine A, gliotoxin, marcfortine A and B, mycophenolic acid, nivalenol, roquefortine A and C and ze …
The method was applied to 20 selected silage samples and alternariol monomethyl ether, andrastin A, alternariol, citreoisocoumarin, deoxyniv …
Validation and application of a liquid chromatography-tandem mass spectrometry based method for the assessment of the co-occurrence of mycotoxins in maize silages from dairy farms in NW Spain.
Dagnac T, Latorre A, Fernández Lorenzo B, Llompart M. Dagnac T, et al. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2016 Dec;33(12):1850-1863. doi: 10.1080/19440049.2016.1243806. Epub 2016 Oct 26. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2016. PMID: 27707355
Zearalenone (ZEA), deoxynivalenol (DON), fumonisins B1 and B2, roquefortine C, alpha-zearalenol, beta-zearalenol, enniatins B and B1, andrastin A, marcfortine A, verruculogen and mycophenolic acid were quantified, the highest average detection frequency being for en …
Zearalenone (ZEA), deoxynivalenol (DON), fumonisins B1 and B2, roquefortine C, alpha-zearalenol, beta-zearalenol, enniatins B and B1, andras …