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Year Number of Results
1988 1
1990 2
1992 2
1993 1
1994 2
1995 1
1996 1
1997 3
1998 3
1999 2
2001 1
2004 1
2007 1
2014 1
2017 1
2019 1
2024 0

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Page 1
Influence of cell confluence on the cAMP signalling pathway in vascular smooth muscle cells.
Belacel-Ouari M, Zhang L, Hubert F, Assaly R, Gerbier R, Jockers R, Dauphin F, Lechêne P, Fischmeister R, Manoury B, Leblais V. Belacel-Ouari M, et al. Cell Signal. 2017 Jul;35:118-128. doi: 10.1016/j.cellsig.2017.03.025. Epub 2017 Apr 4. Cell Signal. 2017. PMID: 28389413
The amplitude of this response, which increased with the concentration of Iso (10 or 100nM), was higher in HD than in LD cells, whatever the Iso concentration used. However, activation of adenylyl cyclase by L-858051 (100muM) induced a similar saturating response in …
The amplitude of this response, which increased with the concentration of Iso (10 or 100nM), was higher in HD than in LD cells, whatever the …
Contribution of BKCa channels to vascular tone regulation by PDE3 and PDE4 is lost in heart failure.
Idres S, Perrin G, Domergue V, Lefebvre F, Gomez S, Varin A, Fischmeister R, Leblais V, Manoury B. Idres S, et al. Cardiovasc Res. 2019 Jan 1;115(1):130-144. doi: 10.1093/cvr/cvy161. Cardiovasc Res. 2019. PMID: 29939224 Free article.
Ro-20-1724 and Cil potentiated the relaxation induced by the beta-adrenergic agonist isoprenaline (ISO) or the adenylyl cyclase activator L-858051 (L85). IBTX abolished the effect of PDE inhibitors on ISO but did not on L85. ...
Ro-20-1724 and Cil potentiated the relaxation induced by the beta-adrenergic agonist isoprenaline (ISO) or the adenylyl cyclase activator …
Role of cAMP inhibition of p44/p42 mitogen-activated protein kinase in potentiation of protein secretion in rat lacrimal gland.
Funaki C, Hodges RR, Dartt DA. Funaki C, et al. Am J Physiol Cell Physiol. 2007 Nov;293(5):C1551-60. doi: 10.1152/ajpcell.00013.2007. Epub 2007 Aug 8. Am J Physiol Cell Physiol. 2007. PMID: 17687004 Free article.
Cellular cAMP levels were increased by 1) using two different cell-permeant cAMP analogs, 2) activating adenylyl cyclase (L-858051), or 3) activation of G(s)-coupled receptors (VIP). The cell-permeant cAMP analogs, L-858051, and VIP inhibited basal p44 …
Cellular cAMP levels were increased by 1) using two different cell-permeant cAMP analogs, 2) activating adenylyl cyclase (L-858051 …
Adenosine receptor-adenylate cyclase system in the trout testis: involvement in the regulation of germ cell proliferation.
Loir M. Loir M. Mol Reprod Dev. 2001 Mar;58(3):307-17. doi: 10.1002/1098-2795(200103)58:3<307::AID-MRD9>3.0.CO;2-F. Mol Reprod Dev. 2001. PMID: 11170272
The increase in cAMP induced by the adenylate cyclase activator L-858051 was inhibited by the adenosine A1)receptor-selective agonists R-N6-(2-phenylisopropyl)adenosine (R-PIA) and N6-cyclopentyladenosine (CPA). ...These data suggest that A(1) and A(2) adenosine rec …
The increase in cAMP induced by the adenylate cyclase activator L-858051 was inhibited by the adenosine A1)receptor-selective …
Control of cytoplasmic and nuclear protein kinase A by phosphodiesterases and phosphatases in cardiac myocytes.
Haj Slimane Z, Bedioune I, Lechêne P, Varin A, Lefebvre F, Mateo P, Domergue-Dupont V, Dewenter M, Richter W, Conti M, El-Armouche A, Zhang J, Fischmeister R, Vandecasteele G. Haj Slimane Z, et al. Cardiovasc Res. 2014 Apr 1;102(1):97-106. doi: 10.1093/cvr/cvu029. Epub 2014 Feb 18. Cardiovasc Res. 2014. PMID: 24550350 Free PMC article.
Similar slow kinetics of nuclear PKA activation was observed upon adenylyl cyclase activation with L-858051 or phosphodiesterase (PDE) inhibition with 3-isobutyl-1-methylxantine. ...
Similar slow kinetics of nuclear PKA activation was observed upon adenylyl cyclase activation with L-858051 or phosphodiestera …
Negative feedback exerted by cAMP-dependent protein kinase and cAMP phosphodiesterase on subsarcolemmal cAMP signals in intact cardiac myocytes: an in vivo study using adenovirus-mediated expression of CNG channels.
Rochais F, Vandecasteele G, Lefebvre F, Lugnier C, Lum H, Mazet JL, Cooper DM, Fischmeister R. Rochais F, et al. J Biol Chem. 2004 Dec 10;279(50):52095-105. doi: 10.1074/jbc.M405697200. Epub 2004 Oct 1. J Biol Chem. 2004. PMID: 15466415 Free article.
In whole cell patch-clamp experiments, the forskolin analogue L-858051 (L-85) elicited a non-selective, Mg2+ -sensitive current observed only in infected cells, which was thus identified as the CNG current (ICNG). ...
In whole cell patch-clamp experiments, the forskolin analogue L-858051 (L-85) elicited a non-selective, Mg2+ -sensitive curren …
Effect of forskolin on bradykinin-induced calcium mobilization in cultured canine tracheal smooth muscle cells.
Luo SF, Chiu CT, Tsao HL, Fan LW, Tsai CT, Pan SL, Yang CM. Luo SF, et al. Cell Signal. 1997 Feb;9(2):159-67. doi: 10.1016/s0898-6568(96)00136-2. Cell Signal. 1997. PMID: 9113415
The inhibitory effects of these agents produced both a depression of the maximal response and a shift to the right of the concentration-response curves of BK. The water-soluble forskolin analogue L-858051, 7-deacetyl-7 beta-(r-N-methylpiperazino)-butyryl forskolin, …
The inhibitory effects of these agents produced both a depression of the maximal response and a shift to the right of the concentration-resp …
Forskolin inhibits 5-hydroxytryptamine-induced phosphoinositide hydrolysis and Ca+2 Mobilisation in canine cultured aorta smooth muscle cells.
Yang CM, Chiu CT, Wang CC, Tsao HL, Fan LW. Yang CM, et al. Cell Signal. 1999 Sep;11(9):697-704. doi: 10.1016/s0898-6568(99)00042-x. Cell Signal. 1999. PMID: 10530879
The inhibitory effect of forskolin resulted from both a depression of the maximal response and a shift to the right of the concentration-effect curves of 5-HT in these responses. The water-soluble forskolin analogue L-858051 [7-deacetyl-7beta-(gamma-N-methylpiperazi …
The inhibitory effect of forskolin resulted from both a depression of the maximal response and a shift to the right of the concentration-eff …
Effect of forskolin on endothelin-induced phosphoinositide hydrolysis and calcium mobilization in cultured canine tracheal smooth muscle cells.
Yang CM, Pan SL, Chiu CT, Lin CC, Hsu YM. Yang CM, et al. J Auton Pharmacol. 1998 Aug;18(4):213-21. doi: 10.1046/j.1365-2680.1998.18485.x. J Auton Pharmacol. 1998. PMID: 9788291
The inhibitory effects of these agents produced both depression of the maximal response and a shift to the right of the concentration-response curve of ET-1 without changing the -logEC50 values. 4. The water-soluble forskolin analogue L-858051, 7-deacetyl-7beta-(gam …
The inhibitory effects of these agents produced both depression of the maximal response and a shift to the right of the concentration-respon …
Regulation of 5-hydroxytryptamine-induced calcium mobilization by cAMP-elevating agents in cultured canine tracheal smooth muscle cells.
Yang C, Tsao HL, Chiu CT, Fan LW, Yu SM. Yang C, et al. Pflugers Arch. 1996 Aug;432(4):708-16. doi: 10.1007/s004240050189. Pflugers Arch. 1996. PMID: 8764973
The inhibitory effects of these agents produced both depression of the maximal response and a shift to the right of the concentration response curves of 5-HT. The water-soluble forskolin analogue L-858051 [7-deacetyl-7beta-(gamma-N-methylpiperazino)-butyryl forskoli …
The inhibitory effects of these agents produced both depression of the maximal response and a shift to the right of the concentration respon …
24 results